| Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease Z Zhang, M Song, X Liu, SS Kang, IS Kwon, DM Duong, NT Seyfried, ... Nature medicine 20 (11), 1254-1262, 2014 | 418 | 2014 |
| Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease Z Zhang, M Song, X Liu, S Su Kang, DM Duong, NT Seyfried, X Cao, ... Nature communications 6 (1), 8762, 2015 | 263 | 2015 |
| FSH blockade improves cognition in mice with Alzheimer’s disease J Xiong, SS Kang, Z Wang, X Liu, TC Kuo, F Korkmaz, A Padilla, ... Nature 603 (7901), 470-476, 2022 | 172 | 2022 |
| Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease Z Zhang, SS Kang, X Liu, EH Ahn, Z Zhang, L He, PM Iuvone, DM Duong, ... Nature structural & molecular biology 24 (8), 632-642, 2017 | 163 | 2017 |
| The prodrug of 7, 8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer’s disease C Chen, Z Wang, Z Zhang, X Liu, SS Kang, Y Zhang, K Ye Proceedings of the National Academy of Sciences 115 (3), 578-583, 2018 | 141 | 2018 |
| Dynamic features of postnatal subventricular zone cell motility: A two‐photon time‐lapse study SC Nam, Y Kim, D Dryanovski, A Walker, G Goings, K Woolfrey, SS Kang, ... Journal of Comparative Neurology 505 (2), 190-208, 2007 | 140 | 2007 |
| Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model C Chen, EH Ahn, SS Kang, X Liu, A Alam, K Ye Science advances 6 (31), eaba0466, 2020 | 126 | 2020 |
| Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer’s disease Z Zhang, O Obianyo, E Dall, Y Du, H Fu, X Liu, SS Kang, M Song, SP Yu, ... Nature communications 8 (1), 14740, 2017 | 121 | 2017 |
| TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson’s disease SS Kang, Z Zhang, X Liu, FP Manfredsson, MJ Benskey, X Cao, J Xu, ... Proceedings of the National Academy of Sciences 114 (40), 10773-10778, 2017 | 109 | 2017 |
| Endogenous CNTF mediates stroke-induced adult CNS neurogenesis in mice SS Kang, MP Keasey, SA Arnold, R Reid, J Geralds, T Hagg Neurobiology of disease 49, 68-78, 2013 | 104 | 2013 |
| α‐Synuclein stimulation of monoamine oxidase‐B and legumain protease mediates the pathology of Parkinson's disease SS Kang, EH Ahn, Z Zhang, X Liu, FP Manfredsson, IM Sandoval, ... The EMBO journal 37 (12), e98878, 2018 | 87 | 2018 |
| Initiation of Parkinson’s disease from gut to brain by δ-secretase EH Ahn, SS Kang, X Liu, G Chen, Z Zhang, B Chandrasekharan, AM Alam, ... Cell research 30 (1), 70-87, 2020 | 80 | 2020 |
| Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus SS Kang, X Liu, EH Ahn, J Xiang, FP Manfredsson, X Yang, HR Luo, ... The Journal of clinical investigation 130 (1), 422-437, 2020 | 79 | 2020 |
| Gut inflammation triggers C/EBPβ/δ‐secretase‐dependent gut‐to‐brain propagation of Aβ and Tau fibrils in Alzheimer’s disease C Chen, Y Zhou, H Wang, A Alam, SS Kang, EH Ahn, X Liu, J Jia, K Ye The EMBO Journal 40 (17), e106320, 2021 | 74 | 2021 |
| δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer’s disease Z Zhang, XG Li, ZH Wang, M Song, SP Yu, SS Kang, X Liu, Z Zhang, ... Molecular psychiatry 26 (2), 586-603, 2021 | 66 | 2021 |
| Akt phosphorylates NQO1 and triggers its degradation, abolishing its antioxidative activities in Parkinson's disease S Luo, SS Kang, ZH Wang, X Liu, JX Day, Z Wu, J Peng, D Xiang, ... Journal of Neuroscience 39 (37), 7291-7305, 2019 | 64 | 2019 |
| Loss of neuron-astroglial interaction rapidly induces protective CNTF expression after stroke in mice SS Kang, MP Keasey, J Cai, T Hagg Journal of Neuroscience 32 (27), 9277-9287, 2012 | 61 | 2012 |
| Inhibition of matrix metalloproteinase-9 attenuated neural progenitor cell migration after photothrombotic ischemia SS Kang, JH Kook, S Hwang, SH Park, SC Nam, JK Kim Brain research 1228, 20-26, 2008 | 45 | 2008 |
| Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features M Jasmin, EH Ahn, MH Voutilainen, J Fombonne, C Guix, T Viljakainen, ... The EMBO journal 40 (3), e105537, 2021 | 44 | 2021 |
| BDNF inhibits neurodegenerative disease–associated asparaginyl endopeptidase activity via phosphorylation by AKT ZH Wang, W Wu, SS Kang, X Liu, Z Wu, J Peng, SP Yu, FP Manfredsson, ... JCI insight 3 (16), 2018 | 43 | 2018 |
