The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant … JS Moreb, D Ucar, S Han, JK Amory, AS Goldstein, B Ostmark, LJ Chang Chemico-biological interactions 195 (1), 52-60, 2012 | 239 | 2012 |
Aldehyde dehydrogenase activity as a functional marker for lung cancer D Ucar, CR Cogle, JR Zucali, B Ostmark, EW Scott, R Zori, BA Gray, ... Chemico-biological interactions 178 (1-3), 48-55, 2009 | 218 | 2009 |
Bone marrow contributes to epithelial cancers in mice and humans as developmental mimicry CR Cogle, ND Theise, DT Fu, D Ucar, S Lee, SM Guthrie, J Lonergan, ... Stem cells 25 (8), 1881-1887, 2007 | 106 | 2007 |
Notch signaling regulates mitochondrial metabolism and NF-κB activity in triple-negative breast cancer cells via IKKα-dependent non-canonical pathways F Hossain, C Sorrentino, DA Ucar, Y Peng, M Matossian, ... Frontiers in oncology 8, 575, 2018 | 96 | 2018 |
Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion Y Gu, S Lin, JL Li, H Nakagawa, Z Chen, B Jin, L Tian, DA Ucar, H Shen, ... Oncogene 31 (4), 469-479, 2012 | 91 | 2012 |
Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth DA Ucar, E Kurenova, TJ Garrett, WG Cance, C Nyberg, A Cox, N Massoll, ... Cell cycle 11 (17), 3250-3259, 2012 | 51 | 2012 |
Notch signaling in myeloid cells as a regulator of tumor immune responses F Hossain, S Majumder, DA Ucar, PC Rodriguez, TE Golde, LM Minter, ... Frontiers in immunology 9, 1288, 2018 | 45 | 2018 |
Targeting of the protein interaction site between FAK and IGF-1R D Zheng, E Kurenova, D Ucar, V Golubovskaya, A Magis, D Ostrov, ... Biochemical and biophysical research communications 388 (2), 301-305, 2009 | 38 | 2009 |
A FAK scaffold inhibitor disrupts FAK and VEGFR-3 signaling and blocks melanoma growth by targeting both tumor and endothelial cells E Kurenova, D Ucar, J Liao, M Yemma, P Gogate, W Bshara, U Sunar, ... Cell cycle 13 (16), 2542-2553, 2014 | 22 | 2014 |
Molecular mechanisms of epithelial to mesenchymal transition regulated by ERK5 signaling AB Bhatt, S Patel, MD Matossian, DA Ucar, L Miele, ME Burow, ... Biomolecules 11 (2), 183, 2021 | 19 | 2021 |
ERK5 is required for tumor growth and maintenance through regulation of the extracellular matrix in triple negative breast cancer VT Hoang, MD Matossian, DA Ucar, S Elliott, J La, MK Wright, HE Burks, ... Frontiers in Oncology 10, 1164, 2020 | 18 | 2020 |
Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor TC Chang, MD Matossian, S Elliott, HE Burks, RA Sabol, DA Ucar, ... PLoS One 15 (10), e0226464, 2020 | 17 | 2020 |
Focal adhesion kinase signaling and function in pancreatic cancer DA Ucar, LH Dang, SN Hochwald Front Biosci (Elite Ed) 3, 750-756, 2011 | 15 | 2011 |
Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple‐negative breast cancer through FRA‐1 regulation VT Hoang, MD Matossian, J La, K Hoang, DA Ucar, S Elliott, HE Burks, ... Journal of cellular biochemistry 122 (8), 835-850, 2021 | 13 | 2021 |
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses G Monticone, Z Huang, F Csibi, S Leit, D Ciccone, AS Champhekar, ... Frontiers in Immunology 13, 987298, 2022 | 11 | 2022 |
Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer AB Bhatt, TD Wright, V Barnes, S Chakrabarty, MD Matossian, E Lexner, ... Translational oncology 14 (6), 101046, 2021 | 10 | 2021 |
Elevated expression of IRS2 in the progression from neurofibroma to malignant peripheral nerve sheath tumor CM Shaw, SR Grobmyer, DA Ucar, WG Cance, JD Reith, SN Hochwald Anticancer research 32 (2), 439-443, 2012 | 7 | 2012 |
Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer F Hossain, DA Ucar, G Monticone, Y Ran, S Majumder, K Larter, H Luu, ... Frontiers in Immunology 14, 1244159, 2023 | 4 | 2023 |
Molecular Mechanisms of Epithelial to Mesenchymal Transition Regulated by ERK5 Signaling. Biomolecules. 2021; 11: 183 AB Bhatt, S Patel, MD Matossian, DA Ucar, L Miele, ME Burow, ... s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | 1 | 2021 |
Abstract P2-03-04: A novel druggable target upstream of Notch: MEK5/ERK5 signaling regulates Jagged-1 and Notch1 expression in triple negative breast cancer stem cells DA Ucar, MD Matossian, VT Hoang-Barnes, FM Hossain, M Gupta, ... Cancer Research 79 (4_Supplement), P2-03-04-P2-03-04, 2019 | 1 | 2019 |