| Perspectives on the current state, challenges, and opportunities in pharmaceutical crystallization process development A Cote, D Erdemir, KP Girard, DA Green, MA Lovette, E Sirota, NK Nere Crystal Growth & Design 20 (12), 7568-7581, 2020 | 69 | 2020 |
| Manufacturing process development for belzutifan, part 5: a streamlined fluorination–dynamic kinetic resolution process T Wang, EM Phillips, SM Dalby, E Sirota, S Axnanda, CS Shultz, P Patel, ... Organic Process Research & Development 26 (3), 543-550, 2021 | 28 | 2021 |
| Process development and control with recent new FBRM, PVM, and IR G Zhou, A Moment, J Cuff, W Schafer, C Orella, E Sirota, X Gong, C Welch Organic Process Research & Development 19 (1), 227-235, 2015 | 28 | 2015 |
| Development of a Robust Manufacturing Route for Molnupiravir, an Antiviral for the Treatment of COVID-19 PS Fier, Y Xu, M Poirier, G Brito, M Zheng, R Bade, E Sirota, K Stone, ... Organic Process Research & Development 25 (12), 2806-2815, 2021 | 21 | 2021 |
| Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 2: Development of a Robust Process for Phenol Synthesis F Peng, GR Humphrey, KM Maloney, D Lehnherr, M Weisel, F Lévesque, ... Organic Process Research & Development 24 (11), 2453-2461, 2020 | 18 | 2020 |
| Development of a commercial manufacturing route to 2-fluoroadenine, the key unnatural nucleobase of islatravir CM Hong, Y Xu, JYL Chung, DM Schultz, M Weisel, RJ Varsolona, ... Organic Process Research & Development 25 (3), 395-404, 2020 | 17 | 2020 |
| Effective control of crystal size via an integrated crystallization, wet milling, and annealing recirculation system W Meng, E Sirota, H Feng, JP McMullen, L Codan, AS Cote Organic Process Research & Development 24 (11), 2639-2650, 2020 | 16 | 2020 |
| Prevalence of impurity retention mechanisms in pharmaceutical crystallizations FL Nordstrom, E Sirota, C Hartmanshenn, TT Kwok, M Paolello, H Li, ... Organic Process Research & Development 27 (4), 723-741, 2023 | 14 | 2023 |
| New reactions and processes for the efficient synthesis of a HCV NS5b prodrug RK Orr, JMMC Dunn, A Nolting, AM Hyde, ER Ashley, J Leone, E Sirota, ... Green Chemistry 20 (11), 2519-2525, 2018 | 14 | 2018 |
| Determining particle‐size distributions from chord length measurements for different particle morphologies J Schoell, R Irizarry, E Sirota, C Mengel, L Codan, A Cote AIChE Journal 65 (5), e16560, 2019 | 12 | 2019 |
| Cross-pharma collaboration for the development of a simulation tool for the model-based digital design of pharmaceutical crystallization processes (CrySiV) B Szilagyi, WL Wu, A Eren, J Mackey, S Kshirsagar, E Szilagyi, ... Crystal Growth & Design 21 (11), 6448-6464, 2021 | 11 | 2021 |
| Crystallization process development for the final step of the biocatalytic synthesis of Islatravir: Comprehensive crystal engineering for a low-dose drug E Sirota, T Kwok, RJ Varsolona, A Whittaker, T Andreani, S Quirie, ... Organic Process Research & Development 25 (2), 308-317, 2021 | 10 | 2021 |
| Improving the filterability of particles by healing the seed particles L Codan, E Sirota, A Cote Organic Process Research & Development 22 (9), 1131-1142, 2018 | 10 | 2018 |
| CRYSTALLIZATION: the pursuit of a robust approach for growing crystals directly to target size A Cote, E Sirota American Pharmaceutical Review 13 (7), 46, 2010 | 8 | 2010 |
| Leveraging Synergistic Solubility in the Development of a Direct Isolation Process for Nemtabrutinib Y Chen, L Iuzzolino, SA Burgess, CK Chung, J Corry, M Crawford, ... Organic Process Research & Development 27 (4), 659-668, 2023 | 6 | 2023 |
| Development of a green and sustainable manufacturing process for gefapixant citrate (MK-7264). Part 6: Development of an improved commercial salt formation process KM Maloney, SW Zhang, AE Mohan, AY Lee, P Larpent, H Ren, ... Organic process research & development 24 (11), 2498-2504, 2020 | 6 | 2020 |
| Preparation of crystalline forms of dihydropyrazolopyrimidinone R Petrova, E Sirota, R Wenslow US Patent 8,703,779, 2014 | 6 | 2014 |
| Manufacturing Process Development for the Biaryl Ether Fragment of Nemtabrutinib (MK-1026) NR Deprez, HB Rose, BK Peters, A Diaz-Santana, Z Liu, N Kuhl, ... Organic Process Research & Development 27 (11), 1965-1974, 2023 | 2 | 2023 |
| Development of an Efficient Route to 2-Ethynylglycerol for the Synthesis of Islatravir SM Rummelt, J Qi, Y Chen, JF Dropinski, G Hughes, JT Kuethe, D Li, ... | 2 | 2021 |
| Concomitant Precipitation of Solid-State Miscible Product-Impurity Phases in Solution Crystallization – Part 2: Industrial Case Studies FL Nordstrom, M Paolello, N Yao, T Armiger, Q Jiang, J Nicholson, J Kratz, ... Organic Process Research & Development, 2024 | 1 | 2024 |
