Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4–AKT–ATP‐binding cassette G2 pathway XQ Wang, WM Ongkeko, L Chen, ZF Yang, P Lu, KK Chen, JP Lopez, ... Hepatology 52 (2), 528-539, 2010 | 290 | 2010 |
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations C Wu, X Miao, L Huang, X Che, G Jiang, D Yu, X Yang, G Cao, Z Hu, ... Nature genetics 44 (1), 62-66, 2012 | 211 | 2012 |
Octamer 4/microRNA‐1246 signaling axis drives Wnt/β‐catenin activation in liver cancer stem cells S Chai, KY Ng, M Tong, EY Lau, TK Lee, KW Chan, YF Yuan, TT Cheung, ... Hepatology 64 (6), 2062-2076, 2016 | 183 | 2016 |
Blocking CDK1/PDK1/β-Catenin signaling by CDK1 inhibitor RO3306 increased the efficacy of sorafenib treatment by targeting cancer stem cells in a preclinical model of … CX Wu, XQ Wang, SH Chok, K Man, SHY Tsang, ACY Chan, KW Ma, ... Theranostics 8 (14), 3737, 2018 | 169 | 2018 |
MDM2 and MDMX bind and stabilize the p53-related protein p73 WM Ongkeko, XQ Wang, WY Siu, AWS Lau, K Yamashita, AL Harris, ... Current Biology 9 (15), 829-832, 1999 | 159 | 1999 |
MDM2 and MDMX can interact differently with ARF and members of the p53 family XQ Wang, T Arooz, WY Siu, CHS Chiu, A Lau, K Yamashita, RYC Poon FEBS letters 490 (3), 202-208, 2001 | 118 | 2001 |
Notch1‐Snail1‐E‐cadherin pathway in metastatic hepatocellular carcinoma XQ Wang, W Zhang, ELH Lui, Y Zhu, P Lu, X Yu, J Sun, S Yang, ... International journal of cancer 131 (3), E163-E172, 2012 | 109 | 2012 |
ATR dependent activation of Chk2 XQ Wang, JL Redpath, ST Fan, EJ Stanbridge Journal of cellular physiology 208 (3), 613-619, 2006 | 97 | 2006 |
CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency XQ Wang, CM Lo, L Chen, ESW Ngan, A Xu, RYC Poon Cell Death & Differentiation 24 (1), 38-48, 2017 | 96 | 2017 |
Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma XQ Wang, JM Luk, PP Leung, BW Wong, EJ Stanbridge, ST Fan Clinical Cancer Research 11 (2), 483-489, 2005 | 96 | 2005 |
A possible role of p73 on the modulation of p53 level through MDM2 XQ Wang, WM Ongkeko, AWS Lau, KM Leung, RYC Poon Cancer research 61 (4), 1598-1603, 2001 | 93 | 2001 |
Gene expression profiling of liver cancer stem cells by RNA-sequencing DWY Ho, ZF Yang, K Yi, CT Lam, MNP Ng, WC Yu, J Lau, T Wan, X Wang, ... PloS one 7 (5), e37159, 2012 | 91 | 2012 |
Pat1: A Topoisomerase II-Associated Protein Required for Faithful Chromosome Transmission in Saccharomyces Cerevisiae X Wang, PM Watt, EJ Louis, RH Borts, ID Hickson Nucleic acids research 24 (23), 4791-4797, 1996 | 85 | 1996 |
Notch inhibitor PF-03084014 inhibits hepatocellular carcinoma growth and metastasis via suppression of cancer stemness due to reduced activation of Notch1–Stat3 CX Wu, A Xu, CC Zhang, P Olson, L Chen, TK Lee, TT Cheung, CM Lo, ... Molecular cancer therapeutics 16 (8), 1531-1543, 2017 | 71 | 2017 |
Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1-and TGF-β/Smad-regulated liver cancer stem cell-like cells W Xia, CM Lo, RYC Poon, TT Cheung, ACY Chan, L Chen, S Yang, ... Oncotarget 8 (24), 38811, 2017 | 63 | 2017 |
The non-coding landscape of head and neck squamous cell carcinoma AE Zou, H Zheng, MA Saad, M Rahimy, J Ku, SZ Kuo, TK Honda, ... Oncotarget 7 (32), 51211, 2016 | 58 | 2016 |
Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines XQ Wang, RK Ng, X Ming, W Zhang, L Chen, ACY Chu, R Pang, CM Lo, ... PloS one 8 (9), e72435, 2013 | 57 | 2013 |
MDM2 and MDMX inhibit the transcriptional activity of ectopically expressed SMAD proteins CH Yam, W Yi Siu, T Arooz, CHS Chiu, A Lau, X Qi Wang, RYC Poon Cancer research 59 (20), 5075-5078, 1999 | 56 | 1999 |
The Pancreatic Microbiome is Associated with Carcinogenesis and Worse Prognosis in Males and Smokers OWM Chakladar J, Kuo SZ, Castaneda G, Li WT, Gnanasekar A, Yu MA, Chang EY ... Cancers (Basel) 12 (9), E2672, 2020 | 54 | 2020 |
Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver XQ Wang, CM Lo, L Chen, CKY Cheung, ZF Yang, YX Chen, MN Ng, ... Hepatology 56 (4), 1557-1566, 2012 | 47 | 2012 |