A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease R Deane, I Singh, AP Sagare, RD Bell, NT Ross, B LaRue, R Love, ... The Journal of clinical investigation 122 (4), 1377-1392, 2012 | 660 | 2012 |
Identification of small molecules for human hepatocyte expansion and iPS differentiation J Shan, RE Schwartz, NT Ross, DJ Logan, D Thomas, SA Duncan, ... Nature chemical biology 9 (8), 514-520, 2013 | 315 | 2013 |
An aldol-based build/couple/pair strategy for the synthesis of medium-and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors LA Marcaurelle, E Comer, S Dandapani, JR Duvall, B Gerard, S Kesavan, ... Journal of the American Chemical Society 132 (47), 16962-16976, 2010 | 227 | 2010 |
A potent and selective quinoxalinone-based STK33 inhibitor does not show synthetic lethality in KRAS-dependent cells M Weïwer, J Spoonamore, J Wei, B Guichard, NT Ross, K Masson, ... ACS medicinal chemistry letters 3 (12), 1034-1038, 2012 | 133 | 2012 |
viridis: Default Color Maps from ‘matplotlib’. R package version 0.5. 1 S Garnier, N Ross, B Rudis, M Sciaini, C Scherer Comprehensive R Archive Network (CRAN), 2018 | 131 | 2018 |
Nannocystin A: an elongation factor 1 inhibitor from myxobacteria with differential anti‐cancer properties P Krastel, S Roggo, M Schirle, NT Ross, F Perruccio, P Aspesi Jr, T Aust, ... Angewandte Chemie International Edition 54 (35), 10149-10154, 2015 | 105 | 2015 |
Synthetic mimetics of protein secondary structure domains NT Ross, WP Katt, AD Hamilton Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010 | 104 | 2010 |
Englerin A agonizes the TRPC4/C5 cation channels to inhibit tumor cell line proliferation C Carson, P Raman, J Tullai, L Xu, M Henault, E Thomas, S Yeola, J Lao, ... PloS one 10 (6), e0127498, 2015 | 103 | 2015 |
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability T Luo, K Masson, JD Jaffe, W Silkworth, NT Ross, CA Scherer, C Scholl, ... Proceedings of the National Academy of Sciences 109 (8), 2860-2865, 2012 | 91 | 2012 |
Synthesis and biological evaluation of a 5-6-5 imidazole-phenyl-thiazole based α-helix mimetic CG Cummings, NT Ross, WP Katt, AD Hamilton Organic letters 11 (1), 25-28, 2009 | 82 | 2009 |
Structure and Function of Benzoylurea‐Derived α‐Helix Mimetics Targeting the Bcl‐xL/Bak Binding Interface JM Rodriguez, NT Ross, WP Katt, D Dhar, G Lee, AD Hamilton ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 649-656, 2009 | 68 | 2009 |
Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold BA Rosenzweig, NT Ross, DM Tagore, J Jayawickramarajah, I Saraogi, ... Journal of the American Chemical Society 131 (14), 5020-5021, 2009 | 68 | 2009 |
Synthetic inhibitors of extended helix–protein interactions based on a biphenyl 4, 4′‐dicarboxamide scaffold JM Rodriguez, L Nevola, NT Ross, G Lee, AD Hamilton ChemBioChem 10 (5), 829-833, 2009 | 68 | 2009 |
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma NT Ross, F Lohmann, S Carbonneau, A Fazal, WA Weihofen, S Gleim, ... Nature chemical biology 16 (1), 50-59, 2020 | 66 | 2020 |
viridis: Default Color Maps from “matplotlib.” 2018 S Garnier, N Ross, B Rudis, M Sciaini, C Scherer R package version 0.5 1, 2019 | 56 | 2019 |
Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex JD Carelli, SG Sethofer, GA Smith, HR Miller, JL Simard, WC Merrick, ... Elife 4, e10222, 2015 | 54 | 2015 |
fasterize: Fast Polygon to Raster Conversion, R package version 1.0. 0 N Ross, M Sumner Computer software]. https://CRAN. R-project. org/package= fasterize, 2020 | 21 | 2020 |
Compositions and methods for selective protein degradation JE Bradner, A Golosov, CP Goold, CPP Guimaraes, MHP Hild, G Motz, ... US Patent 11,999,802, 2024 | 20 | 2024 |
A high content screen in macrophages identifies small molecule modulators of STING-IRF3 and NFkB signaling PD Koch, HR Miller, G Yu, JA Tallarico, PK Sorger, Y Wang, Y Feng, ... ACS chemical biology 13 (4), 1066-1081, 2018 | 19 | 2018 |
In vitro clinical trials: the future of cell-based profiling NT Ross, CJ Wilson Frontiers in pharmacology 5, 93393, 2014 | 19 | 2014 |