ADME evaluation in drug discovery. 4. Prediction of aqueous solubility based on atom contribution approach TJ Hou, K Xia, W Zhang, XJ Xu Journal of chemical information and computer sciences 44 (1), 266-275, 2004 | 306 | 2004 |
ADME evaluation in drug discovery. 5. Correlation of Caco-2 permeation with simple molecular properties TJ Hou, W Zhang, K Xia, XB Qiao, XJ Xu Journal of chemical information and computer sciences 44 (5), 1585-1600, 2004 | 236 | 2004 |
Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE K Xia, M Manning, H Hesham, Q Lin, C Bystroff, W Colón Proceedings of the National Academy of Sciences 104 (44), 17329-17334, 2007 | 97 | 2007 |
Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure K Arnold, Y Xu, EM Sparkenbaugh, M Li, X Han, X Zhang, K Xia, ... Science translational medicine 12 (535), eaav8075, 2020 | 81 | 2020 |
Functional role of glycosaminoglycans in decellularized lung extracellular matrix FE Uhl, F Zhang, RA Pouliot, JJ Uriarte, SR Enes, X Han, Y Ouyang, K Xia, ... Acta biomaterialia 102, 231-246, 2020 | 78 | 2020 |
Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions X Zhang, X Han, K Xia, Y Xu, Y Yang, K Oshima, SM Haeger, MJ Perez, ... Proceedings of the National Academy of Sciences 116 (19), 9208-9213, 2019 | 58 | 2019 |
Biological roles of protein kinetic stability W Colon, J Church, J Sen, J Thibeault, H Trasatti, K Xia Biochemistry 56 (47), 6179-6186, 2017 | 53 | 2017 |
Complete biosynthesis of a sulfated chondroitin in Escherichia coli A Badri, A Williams, A Awofiranye, P Datta, K Xia, W He, K Fraser, ... Nature Communications 12 (1), 1389, 2021 | 52 | 2021 |
Protein aggregation, cardiovascular diseases, and exercise training: Where do we stand? M Gouveia, K Xia, W Colon, SI Vieira, F Ribeiro Ageing research reviews 40, 1-10, 2017 | 46 | 2017 |
Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices JC Silva, MS Carvalho, X Han, K Xia, PE Mikael, JMS Cabral, FC Ferreira, ... Glycoconjugate journal 36, 141-154, 2019 | 45 | 2019 |
Metabolic engineering of cyanobacteria for photoautotrophic production of heparosan, a pharmaceutical precursor of heparin A Sarnaik, MH Abernathy, X Han, Y Ouyang, K Xia, Y Chen, B Cress, ... Algal Research 37, 57-63, 2019 | 42 | 2019 |
Synthetic heparan sulfate standards and machine learning facilitate the development of solid-state nanopore analysis K Xia, JT Hagan, L Fu, BS Sheetz, S Bhattacharya, F Zhang, JR Dwyer, ... Proceedings of the National Academy of Sciences 118 (11), e2022806118, 2021 | 40 | 2021 |
Designed protein reveals structural determinants of extreme kinetic stability A Broom, SM Ma, K Xia, H Rafalia, K Trainor, W Colón, S Gosavi, ... Proceedings of the National Academy of Sciences 112 (47), 14605-14610, 2015 | 39 | 2015 |
Quantifying the kinetic stability of hyperstable proteins via time-dependent SDS trapping K Xia, S Zhang, B Bathrick, S Liu, Y Garcia, W Colón Biochemistry 51 (1), 100-107, 2012 | 32 | 2012 |
Recent advances in biotechnology for heparin and heparan sulfate analysis M Qiao, L Lin, K Xia, J Li, X Zhang, RJ Linhardt Talanta 219, 121270, 2020 | 31 | 2020 |
Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus L Yan, Y Song, K Xia, P He, F Zhang, S Chen, R Pouliot, DJ Weiss, ... Carbohydrate Polymers 260, 117797, 2021 | 30 | 2021 |
Enzymatic synthesis of chondroitin sulfate E to attenuate bacteria lipopolysaccharide-induced organ damage J Li, EM Sparkenbaugh, G Su, F Zhang, Y Xu, K Xia, P He, S Baytas, ... ACS Central Science 6 (7), 1199-1207, 2020 | 30 | 2020 |
Increased 3′‐Phosphoadenosine‐5′‐phosphosulfate Levels in Engineered Escherichia coli Cell Lysate Facilitate the In Vitro Synthesis of Chondroitin Sulfate A A Badri, A Williams, K Xia, RJ Linhardt, MAG Koffas Biotechnology Journal 14 (9), 1800436, 2019 | 29 | 2019 |
Unique Cell Surface Mannan of Yeast Pathogen Candida auris with Selective Binding to IgG L Yan, K Xia, Y Yu, A Miliakos, S Chaturvedi, F Zhang, S Chen, ... ACS infectious diseases 6 (5), 1018-1031, 2020 | 27 | 2020 |
Structural and functional components of the skate sensory organ ampullae of Lorenzini X Zhang, K Xia, L Lin, F Zhang, Y Yu, K St. Ange, X Han, E Edsinger, ... ACS chemical biology 13 (6), 1677-1685, 2018 | 26 | 2018 |