关注
laurent fraisse
laurent fraisse
Research and Development director, DNDI
在 dndi.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Towards the sustainable discovery and development of new antibiotics
M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ...
Nature Reviews Chemistry 5 (10), 726-749, 2021
8662021
Targeting DnaN for tuberculosis therapy using novel griselimycins
A Kling, P Lukat, DV Almeida, A Bauer, E Fontaine, S Sordello, ...
Science 348 (6239), 1106-1112, 2015
3532015
The antimalarial ferroquine: from bench to clinic
C Biot, F Nosten, L Fraisse, D Ter-Minassian, J Khalife, D Dive
Parasite: journal de la Société Française de Parasitologie 18 (3), 207, 2011
1972011
Selection of a trioxaquine as an antimalarial drug candidate
F Coslédan, L Fraisse, A Pellet, F Guillou, B Mordmüller, PG Kremsner, ...
Proceedings of the National Academy of Sciences 105 (45), 17579-17584, 2008
1742008
Probing the role of the covalent linkage of ferrocene into a chloroquine template
C Biot, W Daher, CM Ndiaye, P Melnyk, B Pradines, N Chavain, A Pellet, ...
Journal of medicinal chemistry 49 (15), 4707-4714, 2006
1112006
Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure
W Daher, C Biot, T Fandeur, H Jouin, L Pelinski, E Viscogliosi, L Fraisse, ...
Malaria Journal 5, 1-8, 2006
992006
Indazolecarboxamide derivatives for the treatment and prevention of malaria
H d'Orchymont, L Fraisse, A Zimmermann
US Patent 7,842,711, 2010
962010
Indazolecarboxamide derivatives for the treatment and prevention of malaria
H d'Orchymont, L Fraisse, A Zimmermann
US Patent App. 12/896,203, 2011
942011
Efficacy of NZ2114, a novel plectasin-derived cationic antimicrobial peptide antibiotic, in experimental endocarditis due to methicillin-resistant Staphylococcus aureus
YQ Xiong, WA Hady, A Deslandes, A Rey, L Fraisse, HH Kristensen, ...
Antimicrobial agents and chemotherapy 55 (11), 5325-5330, 2011
852011
A colorimetric 96-well microtiter plate assay for the determination of urate oxidase activity and its kinetic parameters
L Fraisse, MC Bonnet, JP de Farcy, C Agut, D Dersigny, A Bayol
Analytical biochemistry 309 (2), 173-179, 2002
852002
Reliability of antimalarial sensitivity tests depends on drug mechanisms of action
S Wein, M Maynadier, C Tran Van Ba, R Cerdan, S Peyrottes, L Fraisse, ...
Journal of clinical microbiology 48 (5), 1651-1660, 2010
772010
Metallophthalocyanine-catalyzed oxidation of catechols by H2O2 and its surrogates
A Sorokin, L Fraisse, A Rabion, B Meunier
Journal of Molecular Catalysis A: Chemical 117 (1-3), 103-114, 1997
751997
Full-length 5'RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum
B Stadelmayer, A Diederichs, F Chapus, M Rivoire, G Neveu, A Alam, ...
Journal of hepatology 73 (1), 40-51, 2020
742020
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition
E Ballinger, J Mosior, T Hartman, K Burns-Huang, B Gold, R Morris, ...
Science 363 (6426), eaau8959, 2019
732019
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
672023
In Vitro Activity of Ferroquine Is Independent of Polymorphisms in Transport Protein Genes Implicated in Quinoline Resistance in Plasmodium falciparum
M Henry, S Briolant, A Fontaine, J Mosnier, E Baret, R Amalvict, T Fusaï, ...
Antimicrobial agents and chemotherapy 52 (8), 2755-2759, 2008
662008
Long-chain-substituted uric acid and 5, 6-diaminouracil derivatives as novel agents against free radical processes: synthesis and in vitro activity
L Fraisse, JB Verlhac, B Roche, MC Rascle, A Rabion, JL Seris
Journal of Medicinal Chemistry 36 (10), 1465-1473, 1993
601993
Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate
S Wein, M Maynadier, Y Bordat, J Perez, S Maheshwari, P Bette‐Bobillo, ...
British journal of pharmacology 166 (8), 2263-2276, 2012
552012
Observations on the reduction of non-activated carboxylates by Clostridium formicoaceticum with carbon monoxide or formate and the influence of various viologens
L Fraisse, H Simon
Archives of microbiology 150, 381-386, 1988
471988
In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum
W Daher, L Pelinski, S Klieber, F Sadoun, V Meunier, M Bourrié, C Biot, ...
Drug metabolism and disposition 34 (4), 667-682, 2006
442006
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