Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 866 | 2021 |
Targeting DnaN for tuberculosis therapy using novel griselimycins A Kling, P Lukat, DV Almeida, A Bauer, E Fontaine, S Sordello, ... Science 348 (6239), 1106-1112, 2015 | 353 | 2015 |
The antimalarial ferroquine: from bench to clinic C Biot, F Nosten, L Fraisse, D Ter-Minassian, J Khalife, D Dive Parasite: journal de la Société Française de Parasitologie 18 (3), 207, 2011 | 197 | 2011 |
Selection of a trioxaquine as an antimalarial drug candidate F Coslédan, L Fraisse, A Pellet, F Guillou, B Mordmüller, PG Kremsner, ... Proceedings of the National Academy of Sciences 105 (45), 17579-17584, 2008 | 174 | 2008 |
Probing the role of the covalent linkage of ferrocene into a chloroquine template C Biot, W Daher, CM Ndiaye, P Melnyk, B Pradines, N Chavain, A Pellet, ... Journal of medicinal chemistry 49 (15), 4707-4714, 2006 | 111 | 2006 |
Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure W Daher, C Biot, T Fandeur, H Jouin, L Pelinski, E Viscogliosi, L Fraisse, ... Malaria Journal 5, 1-8, 2006 | 99 | 2006 |
Indazolecarboxamide derivatives for the treatment and prevention of malaria H d'Orchymont, L Fraisse, A Zimmermann US Patent 7,842,711, 2010 | 96 | 2010 |
Indazolecarboxamide derivatives for the treatment and prevention of malaria H d'Orchymont, L Fraisse, A Zimmermann US Patent App. 12/896,203, 2011 | 94 | 2011 |
Efficacy of NZ2114, a novel plectasin-derived cationic antimicrobial peptide antibiotic, in experimental endocarditis due to methicillin-resistant Staphylococcus aureus YQ Xiong, WA Hady, A Deslandes, A Rey, L Fraisse, HH Kristensen, ... Antimicrobial agents and chemotherapy 55 (11), 5325-5330, 2011 | 85 | 2011 |
A colorimetric 96-well microtiter plate assay for the determination of urate oxidase activity and its kinetic parameters L Fraisse, MC Bonnet, JP de Farcy, C Agut, D Dersigny, A Bayol Analytical biochemistry 309 (2), 173-179, 2002 | 85 | 2002 |
Reliability of antimalarial sensitivity tests depends on drug mechanisms of action S Wein, M Maynadier, C Tran Van Ba, R Cerdan, S Peyrottes, L Fraisse, ... Journal of clinical microbiology 48 (5), 1651-1660, 2010 | 77 | 2010 |
Metallophthalocyanine-catalyzed oxidation of catechols by H2O2 and its surrogates A Sorokin, L Fraisse, A Rabion, B Meunier Journal of Molecular Catalysis A: Chemical 117 (1-3), 103-114, 1997 | 75 | 1997 |
Full-length 5'RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum B Stadelmayer, A Diederichs, F Chapus, M Rivoire, G Neveu, A Alam, ... Journal of hepatology 73 (1), 40-51, 2020 | 74 | 2020 |
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition E Ballinger, J Mosior, T Hartman, K Burns-Huang, B Gold, R Morris, ... Science 363 (6426), eaau8959, 2019 | 73 | 2019 |
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 67 | 2023 |
In Vitro Activity of Ferroquine Is Independent of Polymorphisms in Transport Protein Genes Implicated in Quinoline Resistance in Plasmodium falciparum M Henry, S Briolant, A Fontaine, J Mosnier, E Baret, R Amalvict, T Fusaï, ... Antimicrobial agents and chemotherapy 52 (8), 2755-2759, 2008 | 66 | 2008 |
Long-chain-substituted uric acid and 5, 6-diaminouracil derivatives as novel agents against free radical processes: synthesis and in vitro activity L Fraisse, JB Verlhac, B Roche, MC Rascle, A Rabion, JL Seris Journal of Medicinal Chemistry 36 (10), 1465-1473, 1993 | 60 | 1993 |
Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate S Wein, M Maynadier, Y Bordat, J Perez, S Maheshwari, P Bette‐Bobillo, ... British journal of pharmacology 166 (8), 2263-2276, 2012 | 55 | 2012 |
Observations on the reduction of non-activated carboxylates by Clostridium formicoaceticum with carbon monoxide or formate and the influence of various viologens L Fraisse, H Simon Archives of microbiology 150, 381-386, 1988 | 47 | 1988 |
In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum W Daher, L Pelinski, S Klieber, F Sadoun, V Meunier, M Bourrié, C Biot, ... Drug metabolism and disposition 34 (4), 667-682, 2006 | 44 | 2006 |