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Matthew Eldridge
Matthew Eldridge
Head of Bioinformatics, Cancer Research UK Cambridge Institute, University of Cambridge
在 cruk.cam.ac.uk 的电子邮件经过验证 - 首页
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引用次数
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Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes
MD Eldridge, CW Murray, TR Auton, GV Paolini, RP Mee
Journal of computer-aided molecular design 11, 425-445, 1997
22171997
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1783*2020
Enhanced detection of circulating tumor DNA by fragment size analysis
F Mouliere, D Chandrananda, AM Piskorz, EK Moore, J Morris, ...
Science translational medicine 10 (466), eaat4921, 2018
8392018
Flexible docking using Tabu search and an empirical estimate of binding affinity
CA Baxter, CW Murray, DE Clark, DR Westhead, MD Eldridge
Proteins: Structure, Function, and Bioinformatics 33 (3), 367-382, 1998
5401998
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds
A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ...
Cell 167 (1), 260-274. e22, 2016
4512016
Entropy-driven formation of a superlattice in a hard-sphere binary mixture
MD Eldridge, PA Madden, D Frenkel
Nature 365 (6441), 35-37, 1993
3941993
Copy number signatures and mutational processes in ovarian carcinoma
G Macintyre, TE Goranova, D De Silva, D Ennis, AM Piskorz, M Eldridge, ...
Nature genetics 50 (9), 1262-1270, 2018
3902018
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis
JMJ Weaver, CS Ross-Innes, N Shannon, AG Lynch, T Forshew, ...
Nature genetics 46 (8), 837-843, 2014
3842014
Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance
M Secrier, X Li, N De Silva, MD Eldridge, G Contino, J Bornschein, ...
Nature genetics 48 (10), 1131-1141, 2016
3662016
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
TS Alioto, I Buchhalter, S Derdak, B Hutter, MD Eldridge, E Hovig, ...
Nature communications 6 (1), 1-13, 2015
3262015
Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma
CS Ross-Innes, J Becq, A Warren, RK Cheetham, H Northen, ...
Nature genetics 47 (9), 1038-1046, 2015
3062015
Cooperative interaction between retinoic acid receptor-α and estrogen receptor in breast cancer
CS Ross-Innes, R Stark, KA Holmes, D Schmidt, C Spyrou, R Russell, ...
Genes & development 24 (2), 171-182, 2010
2832010
Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis
HN March, AG Rust, NA Wright, J ten Hoeve, J de Ridder, M Eldridge, ...
Nature genetics 43 (12), 1202-1209, 2011
2122011
Empirical scoring functions. II. The testing of an empirical scoring function for the prediction of ligand-receptor binding affinities and the use of Bayesian regression to …
CW Murray, TR Auton, MD Eldridge
Journal of computer-aided molecular design 12, 503-519, 1998
2051998
The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic
AM Frankell, SG Jammula, X Li, G Contino, S Killcoyne, S Abbas, J Perner, ...
Nature genetics 51 (3), 506-516, 2019
1962019
Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours
L Harewood, K Kishore, MD Eldridge, S Wingett, D Pearson, ...
Genome biology 18, 1-11, 2017
1632017
Representing and analysing molecular and cellular function using the computer
J Van Helden, A Naim, R Mancuso, M Eldridge, L Wernisch, D Gilbert, ...
Biological chemistry 381 (9/10), 921-936, 2000
1532000
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung
MJ Schuijs, S Png, AC Richard, A Tsyben, G Hamm, J Stockis, C Garcia, ...
Nature immunology 21 (9), 998-1009, 2020
1382020
The stability of the AB 13 crystal in a binary hard sphere system
MD Eldridge, PA Madden, D Frenkel
Molecular physics 79 (1), 105-120, 1993
1281993
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
EK Papachristou, K Kishore, AN Holding, K Harvey, TI Roumeliotis, ...
Nature communications 9 (1), 2311, 2018
1232018
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