Plasma cells are the most abundant gluten peptide MHC-expressing cells in inflamed intestinal tissues from patients with celiac disease LS Høydahl, L Richter, R Frick, O Snir, KS Gunnarsen, OJB Landsverk, ... Gastroenterology 156 (5), 1428-1439. e10, 2019 | 80 | 2019 |
Chimeric anti-CD14 IGG2/4 hybrid antibodies for therapeutic intervention in pig and human models of inflammation C Lau, KS Gunnarsen, LS Høydahl, JT Andersen, G Berntzen, A Pharo, ... The Journal of Immunology 191 (9), 4769-4777, 2013 | 64 | 2013 |
Efficient T cell–B cell collaboration guides autoantibody epitope bias and onset of celiac disease R Iversen, B Roy, J Stamnaes, LS Høydahl, K Hnida, RS Neumann, ... Proceedings of the National Academy of Sciences 116 (30), 15134-15139, 2019 | 55 | 2019 |
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics M Bern, J Nilsen, M Ferrarese, KMK Sand, TT Gjølberg, HE Lode, ... Science translational medicine 12 (565), eabb0580, 2020 | 52 | 2020 |
Targeting the MHC ligandome by use of TCR-like antibodies LS Høydahl, R Frick, I Sandlie, GÅ Løset Antibodies 8 (2), 32, 2019 | 46 | 2019 |
TRIM21 immune signaling is more sensitive to antibody affinity than its neutralization activity S Foss, RE Watkinson, A Grevys, MB McAdam, M Bern, LS Høydahl, ... The Journal of Immunology 196 (8), 3452-3459, 2016 | 42 | 2016 |
A high-affinity human TCR-like antibody detects celiac disease gluten peptide–MHC complexes and inhibits T cell activation R Frick, LS Høydahl, J Petersen, MF Du Pré, S Kumari, G Berntsen, ... Science immunology 6 (62), eabg4925, 2021 | 23 | 2021 |
Multivalent pIX phage display selects for distinct and improved antibody properties LS Høydahl, NR Nilssen, KS Gunnarsen, MF Pré, R Iversen, N Roos, ... Scientific Reports 6 (1), 39066, 2016 | 22 | 2016 |
Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system KS Gunnarsen, LS Høydahl, RS Neumann, K Bjerregaard-Andersen, ... PLoS One 13 (4), e0195868, 2018 | 17 | 2018 |
A TCRα framework–centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions KS Gunnarsen, LS Høydahl, LF Risnes, S Dahal-Koirala, RS Neumann, ... JCI insight 2 (17), 2017 | 17 | 2017 |
Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture K Bjerregaard-Andersen, H Johannesen, N Abdel-Rahman, ... Scientific reports 8 (1), 10836, 2018 | 15 | 2018 |
Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life TT Gjølberg, R Frick, S Mester, S Foss, A Grevys, LS Høydahl, ØK Jørstad, ... Communications Biology 5 (1), 832, 2022 | 12 | 2022 |
Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease C Zhou, T Østerbye, E Bach, S Dahal-Koirala, LS Høydahl, Ø Steinsbø, ... Cell reports 41 (4), 2022 | 10 | 2022 |
CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses IB Rasmussen, I Øynebråten, LS Høydahl, M Flobakk, E Lunde, ... Protein Engineering, Design & Selection 25 (3), 89-96, 2012 | 3 | 2012 |
Generation of circulating autoreactive pre-plasma cells fueled by naïve B cells in celiac disease I Lindeman, LS Høydahl, A Christophersen, LF Risnes, J Jahnsen, ... Cell Reports 43 (4), 2024 | 2 | 2024 |
Affinity maturation of TCR-like antibodies using phage display guided by structural modeling R Frick, LS Høydahl, I Hodnebrug, ES Vik, B Dalhus, LM Sollid, JJ Gray, ... Protein Engineering, Design and Selection 35, gzac005, 2022 | 2 | 2022 |
A TRAV26-1-encoded recognition motif focuses the biased T cell response in celiac disease R Frick, KS Gunnarsen, S Dahal-Koirala, LF Risnes, LM Sollid, I Sandlie, ... European journal of immunology 50 (1), 142-145, 2020 | 2 | 2020 |
ANTIGEN BINDING PROTEINS WHICH BIND TO THE pMHC HLA-DQ2. 5: DQ2. 5 PRESENTING A GLIADIN PEPTIDE GÅ LØset, LS Høydahl, I Sandlie, LM Sollid, R Frick US Patent App. 16/969,679, 2021 | 1 | 2021 |
Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease S Das, J Stamnaes, LS Høydahl, C Skagen, KEA Lundin, J Jahnsen, ... Journal of Autoimmunity 146, 103241, 2024 | | 2024 |
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses LS Høydahl, T Frigstad, IB Rasmussen, I Øynebråten, KW Schjetne, ... Vaccine 39 (11), 1583-1592, 2021 | | 2021 |