Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ... Nature 443 (7110), 421-426, 2006 | 1294 | 2006 |
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche C Lo Celso, HE Fleming, JW Wu, CX Zhao, S Miake-Lye, J Fujisaki, ... Nature 457 (7225), 92-96, 2009 | 1055 | 2009 |
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo HE Fleming, V Janzen, CL Celso, J Guo, KM Leahy, HM Kronenberg, ... Cell stem cell 2 (3), 274-283, 2008 | 630 | 2008 |
Pluripotent stem cell-derived hepatocyte-like cells RE Schwartz, HE Fleming, SR Khetani, SN Bhatia Biotechnology advances 32 (2), 504-513, 2014 | 319 | 2014 |
Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice L Velazquez, AM Cheng, HE Fleming, C Furlonger, S Vesely, A Bernstein, ... The Journal of experimental medicine 195 (12), 1599, 2002 | 267 | 2002 |
Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway HE Fleming, CJ Paige Immunity 15 (4), 521-531, 2001 | 222 | 2001 |
Development of light‐activated CRISPR using guide RNAs with photocleavable protectors PK Jain, V Ramanan, AG Schepers, NS Dalvie, A Panda, HE Fleming, ... Angewandte Chemie International Edition 55 (40), 12440-12444, 2016 | 185 | 2016 |
Modulation of the IL-7 dose-response threshold during pro-B cell differentiation is dependent on pre-B cell receptor expression AJ Marshall, HE Fleming, GE Wu, CJ Paige The Journal of Immunology 161 (11), 6038-6045, 1998 | 177 | 1998 |
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease KR Stevens, MA Scull, V Ramanan, CL Fortin, RR Chaturvedi, KA Knouse, ... Science translational medicine 9 (399), eaah5505, 2017 | 172 | 2017 |
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens S March, V Ramanan, K Trehan, S Ng, A Galstian, N Gural, MA Scull, ... Nature protocols 10 (12), 2027-2053, 2015 | 169 | 2015 |
Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3 V Janzen, HE Fleming, T Riedt, G Karlsson, MJ Riese, CL Celso, ... Cell stem cell 2 (6), 584-594, 2008 | 155 | 2008 |
In vitro culture, drug sensitivity, and transcriptome of Plasmodium vivax hypnozoites N Gural, L Mancio-Silva, AB Miller, A Galstian, VL Butty, SS Levine, ... Cell host & microbe 23 (3), 395-406. e4, 2018 | 149 | 2018 |
Synthetic and living micropropellers for convection-enhanced nanoparticle transport S Schuerle, AP Soleimany, T Yeh, GM Anand, M Häberli, HE Fleming, ... Science advances 5 (4), eaav4803, 2019 | 134 | 2019 |
Cooperation between IL-7 and the pre-B cell receptor: a key to B cell selection HE Fleming, CJ Paige Seminars in immunology 14 (6), 423-430, 2002 | 86 | 2002 |
Mechanisms of selection mediated by interleukin‐7, the preBCR, and hemokinin‐1 during B‐cell development CD Milne, HE Fleming, Y Zhang, CJ Paige Immunological reviews 197 (1), 75-88, 2004 | 67 | 2004 |
Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling JD Kirkpatrick, AD Warren, AP Soleimany, PMK Westcott, JC Voog, ... Science translational medicine 12 (537), eaaw0262, 2020 | 62 | 2020 |
The role of the preBCR, the interleukin‐7 receptor, and homotypic interactions during B‐cell development A Stoddart, HE Fleming, CJ Paige Immunological reviews 175 (1), 47-58, 2000 | 59 | 2000 |
Frontline: IL‐7 does not prevent pro‐B/pre‐B cell maturation to the immature/sIgM+ stage CD Milne, HE Fleming, CJ Paige European journal of immunology 34 (10), 2647-2655, 2004 | 58 | 2004 |
CD45-deficient mice accumulate Pro-B cells both in vivo and in vitro HE Fleming, CD Milne, CJ Paige The Journal of Immunology 173 (4), 2542-2551, 2004 | 48 | 2004 |
Microenvironment-triggered multimodal precision diagnostics L Hao, N Rohani, RT Zhao, EM Pulver, H Mak, OJ Kelada, H Ko, ... Nature Materials 20 (10), 1440-1448, 2021 | 47 | 2021 |