| Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations YS Lee, WD Kennedy, YW Yin Cell 139 (2), 312-324, 2009 | 255 | 2009 |
| Transplantation of endothelial progenitor cells accelerates dermal wound healing with increased recruitment of monocytes/macrophages and neovascularization W Suh, KL Kim, JM Kim, IS Shin, YS Lee, JY Lee, HS Jang, JS Lee, ... Stem cells 23 (10), 1571-1578, 2005 | 220 | 2005 |
| Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass YS Lee, MT Gregory, W Yang Proceedings of the National Academy of Sciences 111 (8), 2954-2959, 2014 | 204 | 2014 |
| Chemical screening identifies ATM as a target for alleviating senescence HT Kang, JT Park, K Choi, Y Kim, HJC Choi, CW Jung, YS Lee, SC Park Nature chemical biology 13 (6), 616-623, 2017 | 160 | 2017 |
| C-reactive protein impairs angiogenic functions and decreases the secretion of arteriogenic chemo-cytokines in human endothelial progenitor cells W Suh, KL Kim, JH Choi, YS Lee, JY Lee, JM Kim, HS Jang, IS Shin, ... Biochemical and biophysical research communications 321 (1), 65-71, 2004 | 121 | 2004 |
| Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence JT Park, YS Lee, KA Cho, SC Park Ageing research reviews 47, 176-182, 2018 | 104 | 2018 |
| Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson‐Gilford progeria syndrome HT Kang, JT Park, K Choi, HJC Choi, CW Jung, GR Kim, YS Lee, SC Park Aging cell 16 (3), 541-550, 2017 | 85 | 2017 |
| Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung YS Lee, J Byun, JA Kim, JS Lee, KL Kim, YL Suh, JM Kim, HS Jang, ... Experimental & molecular medicine 37 (1), 27-35, 2005 | 72 | 2005 |
| Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase MR Szymanski, VB Kuznetsov, C Shumate, Q Meng, YS Lee, G Patel, ... The EMBO journal 34 (14), 1959-1970, 2015 | 66 | 2015 |
| Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage MT Gregory, GY Park, TC Johnstone, YS Lee, W Yang, SJ Lippard Proceedings of the National Academy of Sciences 111 (25), 9133-9138, 2014 | 66 | 2014 |
| Each monomer of the dimeric accessory protein for human mitochondrial DNA polymerase has a distinct role in conferring processivity YS Lee, S Lee, B Demeler, IJ Molineux, KA Johnson, YW Yin Journal of biological chemistry 285 (2), 1490-1499, 2010 | 61 | 2010 |
| A novel ex vivo angiogenesis assay based on electroporation-mediated delivery of naked plasmid DNA to skeletal muscle HS Jang, HJ Kim, JM Kim, YS Lee, KL Kim, JA Kim, JY Lee, W Suh, ... Molecular Therapy 9 (3), 464-474, 2004 | 56 | 2004 |
| Aldosterone upregulates connective tissue growth factor gene expression via p38 MAPK pathway and mineralocorticoid receptor in ventricular myocytes YS Lee, JA Kim, KL Kim, HS Jang, JM Kim, JY Lee, IS Shin, JS Lee, ... Journal of Korean Medical Science 19 (6), 805-811, 2004 | 52 | 2004 |
| How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis YS Lee, Y Gao, W Yang Nature structural & molecular biology 22 (4), 298-303, 2015 | 50 | 2015 |
| A single mutation in human mitochondrial DNA polymerase Pol γA affects both polymerization and proofreading activities of only the holoenzyme YS Lee, KA Johnson, IJ Molineux, YW Yin Journal of biological chemistry 285 (36), 28105-28116, 2010 | 41 | 2010 |
| Alleviation of senescence via ATM inhibition in accelerated aging models MU Kuk, JW Kim, YS Lee, KA Cho, JT Park, SC Park Molecules and cells 42 (3), 210-217, 2019 | 40 | 2019 |
| Adenoviral-mediated delivery of early growth response factor-1 gene increases tissue perfusion in a murine model of hindlimb ischemia YS Lee, HS Jang, JM Kim, JS Lee, JY Lee, KL Kim, IS Shin, W Suh, ... Molecular Therapy 12 (2), 328-336, 2005 | 38 | 2005 |
| Identification of SYK inhibitor, R406 as a novel senolytic agent HJ Cho, EJ Yang, JT Park, JR Kim, EC Kim, KJ Jung, SC Park, YS Lee Aging (Albany NY) 12 (9), 8221, 2020 | 34 | 2020 |
| Disruption of nucleocytoplasmic trafficking as a cellular senescence driver JH Park, SJ Ryu, BJ Kim, HJ Cho, CH Park, HJC Choi, EJ Jang, EJ Yang, ... Experimental & Molecular Medicine 53 (6), 1092-1108, 2021 | 33 | 2021 |
| A DNA-hairpin model for repeat-addition processivity in telomere synthesis W Yang, YS Lee Nature structural & molecular biology 22 (11), 844-847, 2015 | 31 | 2015 |
