Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome X Carvajal-Vergara, A Sevilla, SL D’Souza, YS Ang, C Schaniel, DF Lee, ... Nature 465 (7299), 808-812, 2010 | 815 | 2010 |
Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells D Paull, A Sevilla, H Zhou, AK Hahn, H Kim, C Napolitano, A Tsankov, ... Nature methods 12 (9), 885-892, 2015 | 247 | 2015 |
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity BD MacArthur, A Sevilla, M Lenz, FJ Müller, BM Schuldt, AA Schuppert, ... Nature cell biology 14 (11), 1139-1147, 2012 | 175 | 2012 |
p53 Stabilization and accumulation induced by human vaccinia-related kinase 1 FM Vega, A Sevilla, PA Lazo Molecular and cellular biology, 2004 | 164 | 2004 |
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling DF Lee, J Su, YS Ang, X Carvajal-Vergara, S Mulero-Navarro, CF Pereira, ... Cell stem cell 11 (2), 179-194, 2012 | 156 | 2012 |
Prdm16 is a physiologic regulator of hematopoietic stem cells F Aguilo, S Avagyan, A Labar, A Sevilla, DF Lee, P Kumar, IR Lemischka, ... Blood, The Journal of the American Society of Hematology 117 (19), 5057-5066, 2011 | 152 | 2011 |
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK A Sevilla, CR Santos, FM Vega, PA Lazo Journal of Biological Chemistry 279 (26), 27458-27465, 2004 | 141 | 2004 |
c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK) A Sevilla, CR Santos, R Barcia, FM Vega, PA Lazo Oncogene 23 (55), 8950-8958, 2004 | 127 | 2004 |
Glia crosstalk in neuroinflammatory diseases A Bernaus, S Blanco, A Sevilla Frontiers in cellular neuroscience 14, 209, 2020 | 124 | 2020 |
Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells H Xu, YS Ang, A Sevilla, IR Lemischka, A Ma'ayan PLoS computational biology 10 (8), e1003777, 2014 | 124 | 2014 |
VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma CR Santos, M Rodríguez-Pinilla, FM Vega, JL Rodríguez-Peralto, ... Molecular cancer research 4 (3), 177-185, 2006 | 99 | 2006 |
Myeloid dysregulation in a human induced pluripotent stem cell model of PTPN11-associated juvenile myelomonocytic leukemia S Mulero-Navarro, A Sevilla, AC Roman, DF Lee, SL D’Souza, S Pardo, ... Cell reports 13 (3), 504-515, 2015 | 85 | 2015 |
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal O Binda, A Sevilla, G LeRoy, IR Lemischka, BA Garcia, S Richard Epigenetics 8 (2), 177-183, 2013 | 79 | 2013 |
Post-transcriptional regulation by cytosine-5 methylation of RNA R García-Vílchez, A Sevilla, S Blanco Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1862 (3), 240-252, 2019 | 78 | 2019 |
Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations A Valbuena, I Lopez-Sánchez, FM Vega, A Sevilla, M Sanz-García, ... Archives of biochemistry and biophysics 465 (1), 219-226, 2007 | 65 | 2007 |
Vaccinia-related Kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage M Sanz-García, DM Monsalve, A Sevilla, PA Lazo Journal of Biological Chemistry 287 (28), 23757-23768, 2012 | 64 | 2012 |
Post-translational modifications of the histone variant H2AZ A Sevilla, O Binda Stem cell research 12 (1), 289, 2014 | 56 | 2014 |
Hepatobiliary scintigraphy with SPECT in infancy A Sevilla, R Howman-Giles, H Saleh, J Trpezanovski, R Concannon, ... Clinical nuclear medicine 32 (1), 16-23, 2007 | 55 | 2007 |
Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency DF Lee, J Su, A Sevilla, J Gingold, C Schaniel, IR Lemischka nature protocols 7 (4), 729-748, 2012 | 43 | 2012 |
Pre-and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells L Tan, LA Lacko, T Zhou, D Tomoiaga, R Hurtado, T Zhang, A Sevilla, ... Nature Communications 10 (1), 4155, 2019 | 41 | 2019 |