| Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis RM Wells, CM Jones, Z Xi, A Speer, O Danilchanka, KS Doornbos, P Sun, ... PLoS pathogens 9 (1), e1003120, 2013 | 263 | 2013 |
| The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD J Sun, A Siroy, RK Lokareddy, A Speer, KS Doornbos, G Cingolani, ... Nature structural & molecular biology 22 (9), 672-678, 2015 | 135 | 2015 |
| An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity O Danilchanka, J Sun, M Pavlenok, C Maueröder, A Speer, A Siroy, ... Proceedings of the National Academy of Sciences 111 (18), 6750-6755, 2014 | 134 | 2014 |
| Disulfiram and copper ions kill Mycobacterium tuberculosis in a synergistic manner AG Dalecki, M Haeili, S Shah, A Speer, M Niederweis, O Kutsch, ... Antimicrobial agents and chemotherapy 59 (8), 4835-4844, 2015 | 94 | 2015 |
| PPE Surface Proteins Are Required for Heme Utilization by Mycobacterium tuberculosis A Mitra, A Speer, K Lin, S Ehrt, M Niederweis MBio 8 (1), 10.1128/mbio. 01720-16, 2017 | 92 | 2017 |
| Copper-boosting compounds: a novel concept for antimycobacterial drug discovery A Speer, TB Shrestha, SH Bossmann, RJ Basaraba, GJ Harber, ... Antimicrobial agents and chemotherapy 57 (2), 1089-1091, 2013 | 71 | 2013 |
| Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages A Speer, J Sun, O Danilchanka, V Meikle, JL Rowland, K Walter, BR Buck, ... Molecular microbiology 97 (5), 881-897, 2015 | 69 | 2015 |
| Ectoine biosynthesis in Mycobacterium smegmatis N Ofer, M Wishkautzan, M Meijler, Y Wang, A Speer, M Niederweis, E Gur Applied and environmental microbiology 78 (20), 7483-7486, 2012 | 54 | 2012 |
| Porins increase copper susceptibility of Mycobacterium tuberculosis A Speer, JL Rowland, M Haeili, M Niederweis, F Wolschendorf Journal of bacteriology 195 (22), 5133-5140, 2013 | 47 | 2013 |
| Efficient genome editing in pathogenic mycobacteria using Streptococcus thermophilus CRISPR1-Cas9 AS Meijers, R Troost, R Ummels, J Maaskant, A Speer, S Nejentsev, ... Tuberculosis 124, 101983, 2020 | 30 | 2020 |
| Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection J Sun, K Schaaf, A Duverger, F Wolschendorf, A Speer, F Wagner, ... Oncotarget 7 (13), 15394, 2016 | 27 | 2016 |
| Mycobacterium tuberculosis toxin CpnT is an ESX-5 substrate and requires three type VII secretion systems for intracellular secretion B Izquierdo Lafuente, R Ummels, C Kuijl, W Bitter, A Speer MBio 12 (2), 10.1128/mbio. 02983-20, 2021 | 24 | 2021 |
| Type VII secretion substrates of pathogenic mycobacteria are processed by a surface protease MJ Burggraaf, A Speer, AS Meijers, R Ummels, AM Van Der Sar, ... MBio 10 (5), 10.1128/mbio. 01951-19, 2019 | 23 | 2019 |
| A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis K Schaaf, V Hayley, A Speer, F Wolschendorf, M Niederweis, O Kutsch, ... Assay and drug development technologies 14 (6), 345-354, 2016 | 23 | 2016 |
| Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose M Boot, VJC van Winden, M Sparrius, R van de Weerd, A Speer, ... PLoS genetics 13 (12), e1007131, 2017 | 21 | 2017 |
| iniBAC induction Is Vitamin B12-and MutAB-dependent in Mycobacterium marinum M Boot, M Sparrius, KK Jim, S Commandeur, A Speer, R van de Weerd, ... Journal of Biological Chemistry 291 (38), 19800-19812, 2016 | 20 | 2016 |
| Accelerating early antituberculosis drug discovery by creating mycobacterial indicator strains that predict mode of action M Boot, S Commandeur, AK Subudhi, M Bahira, TC Smith, AM Abdallah, ... Antimicrobial Agents and Chemotherapy 62 (7), 10.1128/aac. 00083-18, 2018 | 18 | 2018 |
| An anti-tuberculosis compound screen using a zebrafish infection model identifies an aspartyl-tRNA synthetase inhibitor E Habjan, VQT Ho, J Gallant, G Van Stempvoort, KK Jim, C Kuijl, ... Disease models & mechanisms 14 (12), dmm049145, 2021 | 17 | 2021 |
| Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier MJ Burggraaf, LS Ates, A Speer, K Van Der Kuij, C Kuijl, W Bitter Microbial cell factories 18, 1-14, 2019 | 13 | 2019 |
| Heterologous Expression of ethA and katG in Mycobacterium marinum Enables the Rapid Identification of New Prodrugs Active against Mycobacterium tuberculosis VQT Ho, T Verboom, MK Rong, E Habjan, W Bitter, A Speer Antimicrobial agents and chemotherapy 65 (4), 10.1128/aac. 01445-20, 2021 | 12 | 2021 |
Michael NiederweisProfessor of Microbiology, University of Alabama at Birmingham在 uab.edu 的电子邮件经过验证
