Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 596 | 2020 |
The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors L Joedicke, J Mao, G Kuenze, C Reinhart, T Kalavacherla, HRA Jonker, ... Nature chemical biology 14 (3), 284-290, 2018 | 88 | 2018 |
Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein G Künze, P Barré, HA Scheidt, L Thomas, D Eliezer, D Huster Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (9), 2302-2313, 2012 | 86 | 2012 |
Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations H Huang, G Kuenze, JA Smith, KC Taylor, AM Duran, A Hadziselimovic, ... Science advances 4 (3), eaar2631, 2018 | 77 | 2018 |
Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state KC Taylor, PW Kang, P Hou, ND Yang, G Kuenze, JA Smith, J Shi, ... Elife 9, e53901, 2020 | 38 | 2020 |
Chemoenzymatic synthesis of nonasulfated tetrahyaluronan with a paramagnetic tag for studying its complex with interleukin‐10 S Köhling, G Künze, K Lemmnitzer, M Bermudez, G Wolber, J Schiller, ... Chemistry–A European Journal 22 (16), 5563-5574, 2016 | 38 | 2016 |
Identification of the glycosaminoglycan binding site of interleukin-10 by NMR spectroscopy G Künze, S Köhling, A Vogel, J Rademann, D Huster Journal of Biological Chemistry 291 (6), 3100-3113, 2016 | 36 | 2016 |
NMR characterization of the binding properties and conformation of glycosaminoglycans interacting with interleukin-10 G Künze, JP Gehrcke, MT Pisabarro, D Huster Glycobiology 24 (11), 1036-1049, 2014 | 34 | 2014 |
Modeling immunity with rosetta: Methods for antibody and antigen design CT Schoeder, S Schmitz, J Adolf-Bryfogle, AM Sevy, JA Finn, MF Sauer, ... Biochemistry 60 (11), 825-846, 2021 | 31 | 2021 |
Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism M Gamble, G Künze, EJ Dodson, KS Wilson, DD Jones Proceedings of the National Academy of Sciences 108 (9), 3536-3541, 2011 | 30 | 2011 |
Integrated structural modeling of full-length LRH-1 reveals inter-domain interactions contribute to receptor structure and function CD Seacrist, G Kuenze, RM Hoffmann, BE Moeller, JE Burke, J Meiler, ... Structure 28 (7), 830-846. e9, 2020 | 27 | 2020 |
Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product PK Richter, P Blázquez-Sánchez, Z Zhao, F Engelberger, C Wiebeler, ... Nature Communications 14 (1), 1905, 2023 | 26 | 2023 |
Integrative protein modeling in RosettaNMR from sparse paramagnetic restraints G Kuenze, R Bonneau, JK Leman, J Meiler Structure 27 (11), 1721-1734. e5, 2019 | 26 | 2019 |
Structures illuminate cardiac ion channel functions in health and in long QT syndrome KR Brewer, G Kuenze, CG Vanoye, AL George Jr, J Meiler, CR Sanders Frontiers in Pharmacology 11, 550, 2020 | 25 | 2020 |
Upgraded molecular models of the human KCNQ1 potassium channel G Kuenze, AM Duran, H Woods, KR Brewer, EF McDonald, CG Vanoye, ... PloS one 14 (9), e0220415, 2019 | 25 | 2019 |
Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family J Vevodova, M Gamble, G Künze, A Ariza, E Dodson, DD Jones, ... Structure 18 (6), 744-755, 2010 | 24 | 2010 |
Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus MP Bhate, T Lemmin, G Kuenze, B Mensa, S Ganguly, JM Peters, ... Journal of the American Chemical Society 140 (24), 7471-7485, 2018 | 22 | 2018 |
Site-specific dynamic nuclear polarization in a Gd (III)-labeled protein J Heiliger, T Matzel, EC Çetiner, H Schwalbe, G Kuenze, B Corzilius Physical Chemistry Chemical Physics 22 (44), 25455-25466, 2020 | 20 | 2020 |
Investigation of the structure of regulatory proteins interacting with glycosaminoglycans by combining NMR spectroscopy and molecular modeling–the beginning of a wonderful … G Künze, D Huster, SA Samsonov Biological chemistry 402 (11), 1337-1355, 2021 | 19 | 2021 |
Structural determinants of cholesterol recognition in helical integral membrane proteins B Marlow, G Kuenze, B Li, CR Sanders, J Meiler Biophysical journal 120 (9), 1592-1604, 2021 | 19 | 2021 |