Repurposing eukaryotic kinase inhibitors as colistin adjuvants in Gram-negative bacteria WT Barker, AM Nemeth, SM Brackett, AK Basak, CE Chandler, LA Jania, ... ACS infectious diseases 5 (10), 1764-1771, 2019 | 31 | 2019 |
Overcoming intrinsic resistance in gram-negative bacteria using small molecule adjuvants RJ Melander, AE Mattingly, AM Nemeth, C Melander Bioorganic & medicinal chemistry letters 80, 129113, 2023 | 18 | 2023 |
Structure–Function Studies on IMD‐0354 Identifies Highly Active Colistin Adjuvants AM Nemeth, AK Basak, AW Weig, SA Marrujo, WT Barker, LA Jania, ... ChemMedChem 15 (2), 210-218, 2020 | 16 | 2020 |
Augmenting the Activity of Macrolide Adjuvants against Acinetobacter baumannii VB Hubble, KR Bartholomew, AW Weig, SM Brackett, SL Barlock, ... ACS Medicinal Chemistry Letters 11 (9), 1723-1731, 2020 | 10 | 2020 |
Dimeric 2-aminoimidazoles are highly active adjuvants for gram-positive selective antibiotics against Acinetobacter baumannii SA Marrujo, VB Hubble, J Yang, M Wang, AM Nemeth, SL Barlock, ... European journal of medicinal chemistry 253, 115329, 2023 | 6 | 2023 |
Re-sensitization of multidrug-resistant and colistin-resistant gram-negative bacteria to colistin by Povarov/Doebner-derived compounds KI Onyedibe, AM Nemeth, N Dayal, RD Smith, J Lamptey, RK Ernst, ... ACS infectious diseases 9 (2), 283-295, 2023 | 2 | 2023 |
Simple dipyrrin analogues of prodigiosin for use as colistin adjuvants K Siwawannapong, AM Nemeth, RJ Melander, J Rong, JR Davis, ... ChemMedChem 17 (16), e202200286, 2022 | 2 | 2022 |
Identification of a 2‐Aminobenzimidazole Scaffold that Potentiates Gram‐Positive Selective Antibiotics Against Gram‐Negative Bacteria AM Nemeth, MM Young, RJ Melander, RD Smith, RK Ernst, C Melander ChemBioChem 25 (8), e202400127, 2024 | 1 | 2024 |
Synthesis, Stereochemical Resolution, and Analogue Synthesis of Variabiline, an Aporphine Alkaloid That Sensitizes Acinetobacter baumannii and Klebsiella pneumoniae to Colistin H Li, AM Nemeth, RJ Melander, C Melander ACS Infectious Diseases 10 (4), 1339-1350, 2024 | | 2024 |