| Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal T Tsuruo, M Naito, A Tomida, N Fujita, T Mashima, H Sakamoto, N Haga Cancer science 94 (1), 15-21, 2003 | 700 | 2003 |
| De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy T Mashima, H Seimiya, T Tsuruo British journal of cancer 100 (9), 1369-1372, 2009 | 619 | 2009 |
| ATP citrate lyase: activation and therapeutic implications in non–small cell lung cancer T Migita, T Narita, K Nomura, E Miyagi, F Inazuka, M Matsuura, ... Cancer research 68 (20), 8547-8554, 2008 | 451 | 2008 |
| Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide L Yang, T Mashima, S Sato, M Mochizuki, H Sakamoto, T Yamori, ... Cancer research 63 (4), 831-837, 2003 | 379 | 2003 |
| Actin cleavage by CPP-32/apopain during the development of apoptosis T Mashima, M Naito, K Noguchi, DK Miller, DW Nicholson, T Tsuruo Oncogene 14 (9), 1007-1012, 1997 | 356 | 1997 |
| A human IAP-family gene, apollon, expressed in human brain cancer cells Z Chen, M Naito, S Hori, T Mashima, T Yamori, T Tsuruo Biochemical and biophysical research communications 264 (3), 847-854, 1999 | 317 | 1999 |
| Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis T Mashima, M Naito, N Fujita, K Noguchi, T Tsuruo Biochemical and biophysical research communications 217 (3), 1185-1192, 1995 | 284 | 1995 |
| c-Jun NH2-terminal kinase-mediated activation of interleukin-1β converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis H Seimiya, T Mashima, M Toho, T Tsuruo Journal of Biological Chemistry 272 (7), 4631-4636, 1997 | 260 | 1997 |
| Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis T Mashima, M Naito, T Tsuruo Oncogene 18 (15), 2423-2430, 1999 | 257 | 1999 |
| ASK1 mediates apoptotic cell death induced by genotoxic stress Z Chen, H Seimiya, M Naito, T Mashima, A Kizaki, S Dan, M Imaizumi, ... Oncogene 18 (1), 173-180, 1999 | 225 | 1999 |
| Aspartate-based inhibitor of interleukin-1β-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells T Mashima, M Naito, S Kataoka, H Kawai, T Tsuruo Biochemical and biophysical research communications 209 (3), 907-915, 1995 | 195 | 1995 |
| Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis H Sakamoto, T Mashima, A Kizaki, S Dan, Y Hashimoto, M Naito, ... Blood, The Journal of the American Society of Hematology 95 (10), 3214-3218, 2000 | 192 | 2000 |
| Modulation of heat-shock protein 27 (Hsp27) anti-apoptotic activity by methylglyoxal modification H Sakamoto, T Mashima, K Yamamoto, T Tsuruo Journal of Biological Chemistry 277 (48), 45770-45775, 2002 | 167 | 2002 |
| Selective Activation of Apoptosis Program by S-p-bromobenzylglutathione Cyclopentyl Diester in Glyoxalase I-overexpressing Human Lung Cancer Cells H Sakamoto, T Mashima, S Sato, Y Hashimoto, T Yamori, T Tsuruo Clinical cancer research 7 (8), 2513-2518, 2001 | 164 | 2001 |
| Phosphatidylserine externalization is a downstream event of interleukin-1β–converting enzyme family protease activation during apoptosis M Naito, K Nagashima, T Mashima, T Tsuruo Blood, The Journal of the American Society of Hematology 89 (6), 2060-2066, 1997 | 162 | 1997 |
| Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling V Syed, K Mukherjee, J Lyons-Weiler, KM Lau, T Mashima, T Tsuruo, ... Oncogene 24 (10), 1774-1787, 2005 | 151 | 2005 |
| Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent‐induced apoptosis T Mashima, S Udagawa, T Tsuruo Journal of cellular physiology 188 (3), 352-358, 2001 | 137 | 2001 |
| p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target T Mashima, T Oh-hara, S Sato, M Mochizuki, Y Sugimoto, K Yamazaki, ... Journal of the National Cancer Institute 97 (10), 765-777, 2005 | 136 | 2005 |
| Imaging of caspase‐3 activation in HeLa cells stimulated with etoposide using a novel fluorescent probe S Mizukami, K Kikuchi, T Higuchi, Y Urano, T Mashima, T Tsuruo, ... FEBS letters 453 (3), 356-360, 1999 | 133 | 1999 |
| Molecular cloning and functional analysis of apoxin I, a snake venom-derived apoptosis-inducing factor with L-amino acid oxidase activity S Torii, K Yamane, T Mashima, N Haga, K Yamamoto, JW Fox, M Naito, ... Biochemistry 39 (12), 3197-3205, 2000 | 131 | 2000 |
