Human POLB gene is mutated in high percentage of colorectal tumors KA Donigan, K Sun, AA Nemec, DL Murphy, X Cong, V Northrup, ... Journal of Biological Chemistry 287 (28), 23830-23839, 2012 | 109 | 2012 |
Variant base excision repair proteins: contributors to genomic instability AA Nemec, SS Wallace, JB Sweasy Seminars in cancer biology 20 (5), 320-328, 2010 | 98 | 2010 |
Neovascularization and angiogenic gene expression following chronic arsenic exposure in mice NV Soucy, D Mayka, LR Klei, AA Nemec, JA Bauer, A Barchowsky Cardiovascular toxicology 5, 29-41, 2005 | 85 | 2005 |
A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation J Yamtich, AA Nemec, A Keh, JB Sweasy PLoS genetics 8 (11), e1003052, 2012 | 80 | 2012 |
Autophagic clearance of proteasomes in yeast requires the conserved sorting nexin Snx4 AA Nemec, LA Howell, AK Peterson, MA Murray, RJ Tomko Journal of Biological Chemistry 292 (52), 21466-21480, 2017 | 76 | 2017 |
Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells AA Nemec, GD Leikauf, BR Pitt, KJ Wasserloos, A Barchowsky American journal of respiratory cell and molecular biology 41 (1), 69-75, 2009 | 64 | 2009 |
Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation AA Nemec, KA Donigan, DL Murphy, J Jaeger, JB Sweasy Journal of Biological Chemistry 287 (28), 23840-23849, 2012 | 56 | 2012 |
Cr (VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck KA O'hara, RJ Vaghjiani, AA Nemec, LR Klei, A Barchowsky Biochemical Journal 402 (2), 261-269, 2007 | 44 | 2007 |
Chromium (VI) inhibits heme oxygenase‐1 expression in vivo and in arsenic‐exposed human airway epithelial cells KA O'Hara, AA Nemec, J Alam, LR Klei, BT Mossman, A Barchowsky Journal of cellular physiology 209 (1), 113-121, 2006 | 36 | 2006 |
Microbial Stimulation by Mycoplasma fermentans Synergistically Amplifies IL-6 Release by Human Lung Fibroblasts in Response to Residual Oil Fly Ash (ROFA … F Gao, A Barchowsky, AA Nemec, JP Fabisiak Toxicological Sciences 81 (2), 467-479, 2004 | 29 | 2004 |
The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation HA Galick, CG Marsden, S Kathe, JA Dragon, L Volk, AA Nemec, ... Oncotarget 8 (49), 85883, 2017 | 26 | 2017 |
The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency AA Nemec, DL Murphy, KA Donigan, JB Sweasy Journal of Biological Chemistry 289 (20), 13708-13716, 2014 | 25 | 2014 |
DNA polymerase beta germline variant confers cellular response to cisplatin therapy AA Nemec, L Abriola, JS Merkel, E de Stanchina, M DeVeaux, ... Molecular Cancer Research 15 (3), 269-280, 2017 | 24 | 2017 |
An allosteric interaction network promotes conformation state-dependent eviction of the Nas6 assembly chaperone from nascent 26S proteasomes AA Nemec, AK Peterson, JL Warnock, RG Reed, RJ Tomko Cell reports 26 (2), 483-495. e5, 2019 | 22 | 2019 |
Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks J Rozacky, AA Nemec, JB Sweasy, D Kidane Oncotarget 6 (27), 24474, 2015 | 20 | 2015 |
A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation A Sjolund, AA Nemec, N Paquet, A Prakash, P Sung, S Doublie, ... PLoS genetics 10 (11), e1004753, 2014 | 20 | 2014 |
Chromium (VI) stimulates Fyn to initiate innate immune gene induction in human airway epithelial cells AA Nemec, LM Zubritsky, A Barchowsky Chemical research in toxicology 23 (2), 396-404, 2010 | 20 | 2010 |
Signal transducer and activator of transcription 1 (STAT1) is essential for chromium silencing of gene induction in human airway epithelial cells AA Nemec, A Barchowsky Toxicological sciences 110 (1), 212-223, 2009 | 18 | 2009 |
Remote mutations induce functional changes in active site residues of human DNA polymerase β BE Eckenroth, JB Towle-Weicksel, AA Nemec, DL Murphy, JB Sweasy, ... Biochemistry 56 (18), 2363-2371, 2017 | 13 | 2017 |
Estrogen drives cellular transformation and mutagenesis in cells expressing the breast cancer–associated R438W DNA polymerase lambda protein AA Nemec, KB Bush, JB Towle-Weicksel, BF Taylor, V Schulz, ... Molecular Cancer Research 14 (11), 1068-1077, 2016 | 13 | 2016 |