E3 ubiquitin ligase VHL regulates hypoxia-inducible factor-1α to maintain regulatory T cell stability and suppressive capacity JH Lee, C Elly, Y Park, YC Liu Immunity 42 (6), 1062-1074, 2015 | 214 | 2015 |
IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis P Krause, V Morris, JA Greenbaum, Y Park, U Bjoerheden, Z Mikulski, ... Nature communications 6 (1), 7055, 2015 | 140 | 2015 |
TSC1 regulates the balance between effector and regulatory T cells Y Park, HS Jin, J Lopez, C Elly, G Kim, M Murai, M Kronenberg, YC Liu The Journal of clinical investigation 123 (12), 5165-5178, 2013 | 135 | 2013 |
H-Ras is degraded by Wnt/β-catenin signaling via β-TrCP-mediated polyubiquitylation SE Kim, JY Yoon, WJ Jeong, SH Jeon, Y Park, JB Yoon, YN Park, H Kim, ... Journal of cell science 122 (6), 842-848, 2009 | 110 | 2009 |
TIGIT/CD226 axis regulates anti-tumor immunity J Yeo, M Ko, DH Lee, Y Park, H Jin Pharmaceuticals 14 (3), 200, 2021 | 96 | 2021 |
Itch expression by Treg cells controls Th2 inflammatory responses H Jin, Y Park, C Elly, YC Liu The Journal of clinical investigation 123 (11), 4923-4934, 2013 | 96 | 2013 |
TIP120A associates with cullins and modulates ubiquitin ligase activity KW Min, JW Hwang, JS Lee, Y Park, T Tamura, JB Yoon Journal of Biological Chemistry 278 (18), 15905-15910, 2003 | 93 | 2003 |
Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling H Jin, L Liao, Y Park, YC Liu Proceedings of the National Academy of Sciences 110 (2), 624-629, 2013 | 83 | 2013 |
The ubiquitin system in immune regulation Y Park, H Jin, D Aki, J Lee, YC Liu Advances in immunology 124, 17-66, 2014 | 82 | 2014 |
Osmotic stress inhibits proteasome by p38 MAPK-dependent phosphorylation SH Lee, Y Park, SK Yoon, JB Yoon Journal of Biological Chemistry 285 (53), 41280-41289, 2010 | 82 | 2010 |
The HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathway Y Park, SK Yoon, JB Yoon Journal of Biological Chemistry 284 (3), 1540-1549, 2009 | 79 | 2009 |
CD226hiCD8+ T Cells Are a Prerequisite for Anti-TIGIT Immunotherapy H Jin, M Ko, D Choi, JH Kim, D Lee, SH Kang, I Kim, HJ Lee, EK Choi, ... Cancer immunology research 8 (7), 912-925, 2020 | 71 | 2020 |
Regulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complex Y Park, H Jin, YC Liu Proceedings of the National Academy of Sciences 110 (23), 9433-9438, 2013 | 66 | 2013 |
CAND1 enhances deneddylation of CUL1 by COP9 signalosome KW Min, MJ Kwon, HS Park, Y Park, SK Yoon, JB Yoon Biochemical and biophysical research communications 334 (3), 867-874, 2005 | 60 | 2005 |
SHARPIN controls regulatory T cells by negatively modulating the T cell antigen receptor complex Y Park, H Jin, J Lopez, J Lee, L Liao, C Elly, YC Liu Nature immunology 17 (3), 286-296, 2016 | 58 | 2016 |
Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases Y Park, YP Hwang, JS Lee, SH Seo, SK Yoon, JB Yoon Molecular and cellular biology 25 (9), 3842-3853, 2005 | 56 | 2005 |
Mucin1 and Mucin16: therapeutic targets for cancer therapy DH Lee, S Choi, Y Park, H Jin Pharmaceuticals 14 (10), 1053, 2021 | 54 | 2021 |
The ubiquitin E3/E4 ligase UBE4A adjusts protein ubiquitylation and accumulation at sites of DNA damage, facilitating double-strand break repair K Baranes-Bachar, A Levy-Barda, J Oehler, DA Reid, I Soria-Bretones, ... Molecular cell 69 (5), 866-878. e7, 2018 | 54 | 2018 |
Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy H Jin, Y Park BMB reports 54 (1), 2, 2021 | 50 | 2021 |
LAG-3xPD-L1 bispecific antibody potentiates antitumor responses of T cells through dendritic cell activation E Sung, M Ko, J Won, Y Jo, E Park, H Kim, E Choi, U Jung, J Jeon, Y Kim, ... Molecular Therapy 30 (8), 2800-2816, 2022 | 46 | 2022 |