Sertoli cell number defines and predicts germ and Leydig cell population sizes in the adult mouse testis D Rebourcet, A Darbey, A Monteiro, U Soffientini, YT Tsai, I Handel, ... Endocrinology 158 (9), 2955-2969, 2017 | 138 | 2017 |
Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics SH Patel, L O’Hara, N Atanassova, SE Smith, MK Curley, D Rebourcet, ... Scientific reports 7 (1), 8991, 2017 | 59 | 2017 |
Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production D Rebourcet, R Mackay, A Darbey, MK Curley, A Jørgensen, ... The FASEB Journal 34 (8), 10373, 2020 | 43 | 2020 |
Specific transcriptomic signatures and dual regulation of steroidogenesis between fetal and adult mouse Leydig cells P Sararols, I Stévant, Y Neirijnck, D Rebourcet, A Darbey, MK Curley, ... Frontiers in Cell and Developmental Biology 9, 695546, 2021 | 22 | 2021 |
Leukemia inhibitory factor-receptor is dispensable for prenatal testis development but is required in Sertoli cells for normal spermatogenesis in mice M Curley, L Milne, S Smith, N Atanassova, D Rebourcet, A Darbey, ... Scientific reports 8 (1), 11532, 2018 | 19 | 2018 |
A comparison of in vivo viral targeting systems identifies adeno‐associated virus serotype 9 (AAV9) as an effective vector for genetic manipulation of Leydig cells in adult mice A Darbey, D Rebourcet, M Curley, K Kilcoyne, N Jeffery, N Reed, L Milne, ... Andrology 9 (1), 460-473, 2021 | 9 | 2021 |
Deliverable transgenics & gene therapy possibilities for the testes A Darbey, LB Smith Molecular and cellular endocrinology 468, 81-94, 2018 | 6 | 2018 |
Testicular cell selective ablation using diphtheria toxin receptor transgenic mice D Rebourcet, A Darbey, M Curley, P O’Shaughnessy, LB Smith Sertoli Cells: Methods and Protocols, 203-228, 2018 | 5 | 2018 |
A novel model using AAV9-cre to knockout adult leydig cell gene expression reveals a physiological role of glucocorticoid receptor signalling in leydig cell function AL Gannon, AL Darbey, G Chensee, BM Lawrence, L O’Donnell, J Kelso, ... International Journal of Molecular Sciences 23 (23), 15015, 2022 | 4 | 2022 |
Leukemia inhibitory factor-receptor signalling negatively regulates gonadotrophin-stimulated testosterone production in mouse Leydig Cells M Curley, A Darbey, L O'Donnell, KR Kilcoyne, K Wilson, W Mungall, ... Molecular and Cellular Endocrinology 544, 111556, 2022 | 2 | 2022 |
Creation of de novo cryptic splicing for ALS/FTD precision medicine OG Wilkins, MZYJ Chien, JJ Wlaschin, M Pisliakova, D Thompson, ... bioRxiv, 2023 | 1 | 2023 |
Refining gene delivery to skeletal muscle with a dual-strategy approach of muscle-tropic AAV capsids and muscle-specific promoters. A Darbey, W Jin, L Greensmith, JN Sleigh, J Counsell, P Fratta bioRxiv, 2024.08. 02.605568, 2024 | | 2024 |
Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid L O’Donnell, LF Dagley, M Curley, A Darbey, PJ O’Shaughnessy, ... Plos one 18 (9), e0290846, 2023 | | 2023 |
Targeting and repair of adult testicular somatic cells through viral gene therapy AL Darbey University of Edinburgh, 2018 | | 2018 |
Acute reduction of Sertoli cell numbers during development leads to a subsequent reduction in sperm numbers in adulthood AL Darbey, O Peter, JL Pitetti, S Nef, L Smith, D Rebourcet Reproduction Abstracts 1, 2014 | | 2014 |