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Merlin Nithya Gnanapragasam
Merlin Nithya Gnanapragasam
Assistant Professor, Center for Gene Regulation in Health and Disease, Cleveland State University
在 csuohio.edu 的电子邮件经过验证 - 首页
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p66α–MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2–NuRD complex
MN Gnanapragasam, JN Scarsdale, ML Amaya, HD Webb, MA Desai, ...
Proceedings of the National Academy of Sciences 108 (18), 7487-7492, 2011
1602011
Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells
M Amaya, M Desai, MN Gnanapragasam, SZ Wang, S Zu Zhu, ...
Blood, The Journal of the American Society of Hematology 121 (17), 3493-3501, 2013
962013
Erythroid transcription factor EKLF/KLF1 mutation causing congenital dyserythropoietic anemia type IV in a patient of Taiwanese origin: review of all reported cases and …
JA Jaffray, WB Mitchell, MN Gnanapragasam, SV Seshan, X Guo, ...
Blood Cells, Molecules, and Diseases 51 (2), 71-75, 2013
842013
EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation
MN Gnanapragasam, KE McGrath, S Catherman, L Xue, J Palis, JJ Bieker
Blood, The Journal of the American Society of Hematology 128 (12), 1631-1641, 2016
832016
A systems approach identifies essential FOXO3 functions at key steps of terminal erythropoiesis
R Liang, G Campreciós, Y Kou, K McGrath, R Nowak, S Catherman, ...
PLoS genetics 11 (10), e1005526, 2015
652015
Orchestration of late events in erythropoiesis by KLF1/EKLF
MN Gnanapragasam, JJ Bieker
Current opinion in hematology 24 (3), 183-190, 2017
592017
Methyl-binding domain protein 2–dependent proliferation and survival of breast cancer cells
OY Mian, SZ Wang, SZ Zhu, MN Gnanapragasam, L Graham, HD Bear, ...
Molecular Cancer Research 9 (8), 1152-1162, 2011
552011
The role of the epigenetic signal, DNA methylation, in gene regulation during erythroid development
GD Ginder, MN Gnanapragasam, OY Mian
Current topics in developmental biology 82, 85-116, 2008
392008
Extrinsic and intrinsic control by EKLF (KLF1) within a specialized erythroid niche
L Xue, M Galdass, MN Gnanapragasam, D Manwani, JJ Bieker
Development 141 (11), 2245-2254, 2014
362014
EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis
K Mukherjee, L Xue, A Planutis, MN Gnanapragasam, A Chess, JJ Bieker
Elife 10, e61070, 2021
252021
MBD2 contributes to developmental silencing of the human ε-globin gene
JW Rupon, SZ Wang, M Gnanapragasam, S Labropoulos, GD Ginder
Blood Cells, Molecules, and Diseases 46 (3), 212-219, 2011
192011
Survey and evaluation of mutations in the human KLF1 transcription unit
MN Gnanapragasam, JD Crispino, AM Ali, R Weinberg, R Hoffman, ...
Scientific reports 8 (1), 6587, 2018
102018
Case report of erythroid transcription factor EKLF mutation causing a rare form of congenital dyserythropoetic anemia in a patient of Taiwanese origin
WB Mitchell, MN Gnanapragasam, JA Jaffray, JJ Bieker, D Manwani
Blood 118 (21), 2154, 2011
82011
PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin
R Elagooz, AR Dhara, RM Gott, SE Adams, RA White, A Ghosh, ...
Blood Advances 6 (23), 6016-6022, 2022
52022
Identification of a genomic DNA sequence that quantitatively modulates KLF1 transcription factor expression in differentiating human hematopoietic cells
MN Gnanapragasam, A Planutis, JA Glassberg, JJ Bieker
Scientific Reports 13 (1), 7589, 2023
42023
Alternative splicing of EKLF/KLF1 in murine primary erythroid tissues
YY Yien, MN Gnanapragasam, R Gupta, S Rivella, JJ Bieker
Experimental hematology 43 (1), 65-70, 2015
42015
a, Walavalkar, NM, Wang, SZ, Zu Zhu, S., Ginder, GD, and Williams, DC (2011) p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene …
MN Gnanapragasam, JN Scarsdale, ML Amaya, HD Webb, M Desai
Proc. Natl. Acad. Sci. US A 108, 7487-92, 0
4
Delineating the Functions of Cohesin Stag1 during Terminal Erythroid Differentiation
S Adams, A Dhara, R White, A Prabahar, P Jiang, MN Gnanapragasam, ...
Blood 142 (Supplement 1), 1107-1107, 2023
2023
Compositions and methods of treatment of sickle cell anemia and beta-thalassemia
MN Gnanapragasam, M Ramamoorthy
US Patent App. 17/987,058, 2023
2023
Identification of a genomic DNA sequence that quantitatively modulates KLF1 expression in differentiating human hematopoietic cells
MN Gnanapragasam, A Planutis, JA Glassberg, JJ Bieker
bioRxiv, 2021.11. 22.469597, 2021
2021
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