Long QT Syndrome Type 2: Emerging Strategies for Correcting Class 2 KCNH2 (hERG) Mutations and Identifying New Patients M Ono, DE Burgess, EA Schroder, CS Elayi, CL Anderson, CT January, ... Biomolecules 10 (8), 1144, 2020 | 38 | 2020 |
Lipid-dependent alternating access mechanism of a bacterial multidrug ABC exporter K Immadisetty, J Hettige, M Moradi ACS Central Science 5 (1), 43-56, 2019 | 32 | 2019 |
New design strategies for antidepressant drugs K Immadisetty, LM Geffert, CK Surratt, JD Madura Expert opinion on drug discovery 8 (11), 1399-1414, 2013 | 31 | 2013 |
What can and cannot be learned from molecular dynamics simulations of bacterial proton-coupled oligopeptide transporter GkPOT? K Immadisetty, J Hettige, M Moradi The Journal of Physical Chemistry B 121 (15), 3644-3656, 2017 | 27 | 2017 |
Pathogenic variants in TNNC2 cause congenital myopathy due to an impaired force response to calcium M van de Locht, S Donkervoort, JM de Winter, S Conijn, L Begthel, ... The Journal of clinical investigation 131 (9), 2021 | 20* | 2021 |
A review of monoamine transporter-ligand interactions K Immadisetty, J D Madura Current computer-aided drug design 9 (4), 556-568, 2013 | 18 | 2013 |
The role of a crystallographically unresolved cytoplasmic loop in stabilizing the bacterial membrane insertase yidc2 T Harkey, V Govind Kumar, J Hettige, SH Tabari, K Immadisetty, M Moradi Scientific reports 9 (1), 14451, 2019 | 14 | 2019 |
Structural changes beyond the EF-hand contribute to apparent calcium binding affinities: insights from parvalbumins K Immadisetty, B Sun, PM Kekenes-Huskey The Journal of Physical Chemistry B 125 (24), 6390-6405, 2021 | 11 | 2021 |
An investigation of the YidC-mediated membrane insertion of Pf3 coat protein using molecular dynamics simulations A Polasa, JJ Hettige, K Immadisetty, M Moradi Frontiers in Molecular Biosciences, 2022 | 7* | 2022 |
Elucidating the molecular basis of spontaneous activation in an engineered mechanosensitive channel K Immadisetty, A Polasa, R Shelton, M Moradi Computational and Structural Biotechnology Journal 20, 2539-2550, 2022 | 7* | 2022 |
Modulation of P2X4 pore closure by magnesium, potassium, and ATP K Immadisetty, J Alenciks, PM Kekenes-Huskey Biophysical Journal 121 (7), 1134-1142, 2022 | 6 | 2022 |
Mechanistic Picture for Chemomechanical Coupling in a Bacterial Proton-Coupled Oligopeptide Transporter from Streptococcus Thermophilus K Immadisetty, M Moradi The Journal of Physical Chemistry B, 2021 | 4 | 2021 |
Recent breakthroughs in computational structural biology harnessing the power of sequences and structures B Mészáros, E Park, D Malinverni, BI Sejdiu, K Immadisetty, M Sandhu, ... Current Opinion in Structural Biology 80, 102608, 2023 | 3 | 2023 |
Conformational Transition Pathways in Major Facilitator Superfamily Transporters D Ogden, K Immadisetty, M Moradi bioRxiv, 708289, 2019 | 3 | 2019 |
Prediction of Kv11. 1 potassium channel PAS-domain variants trafficking via machine learning K Immadisetty, X Fang, G San Ramon, CM Hartle, TP McCoy, RG Center, ... Journal of Molecular and Cellular Cardiology 180, 69-83, 2023 | 2 | 2023 |
Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity JT Zoine, K Immadisetty, J Ibanez-Vega, SE Moore, C Nevitt, U Thanekar, ... Cell Reports Medicine 5 (2), 2024 | 1 | 2024 |
Modeling the binding of inhibitors/drugs to the human serotonin transporter K Immadisetty | 1 | 2015 |
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease S Donkervoort, M van de Locht, D Ronchi, J Reunert, CA McLean, M Zaki, ... Science Translational Medicine 16 (741), eadg2841, 2024 | | 2024 |
Rapid metabolic regulation of a novel arginine methylation of KCa3. 1 attenuates T cell exhaustion. P Sharma, A Guo, E Boada Romero, S Poudel, KC Verbist, G Palacios, ... bioRxiv, 2024.05. 09.593421, 2024 | | 2024 |
Importance of AB domain in parvalbumins’ calcium binding affinity K Immadisetty, J Jacob-Dolan bioRxiv, 2022.05. 27.493786, 2022 | | 2022 |