Blood–brain barrier: structural components and function under physiologic and pathologic conditions Y Persidsky, SH Ramirez, J Haorah, GD Kanmogne Journal of Neuroimmune Pharmacology 1, 223-236, 2006 | 1057 | 2006 |
The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier TP Buzhdygan, BJ DeOre, A Baldwin-Leclair, TA Bullock, HM McGary, ... Neurobiology of disease 146, 105131, 2020 | 483 | 2020 |
Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood–brain barrier dysfunction J Haorah, SH Ramirez, K Schall, D Smith, R Pandya, Y Persidsky Journal of neurochemistry 101 (2), 566-576, 2007 | 409 | 2007 |
Mechanism of alcohol-induced oxidative stress and neuronal injury J Haorah, SH Ramirez, N Floreani, S Gorantla, B Morsey, Y Persidsky Free Radical Biology and Medicine 45 (11), 1542-1550, 2008 | 382 | 2008 |
Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells M Yamamoto, SH Ramirez, S Sato, T Kiyota, RL Cerny, K Kaibuchi, ... The American journal of pathology 172 (2), 521-533, 2008 | 289 | 2008 |
Activation of cannabinoid receptor 2 attenuates leukocyte–endothelial cell interactions and blood–brain barrier dysfunction under inflammatory conditions SH Ramirez, J Haskó, A Skuba, S Fan, H Dykstra, R McCormick, ... Journal of Neuroscience 32 (12), 4004-4016, 2012 | 259 | 2012 |
Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier MJ Bernas, FL Cardoso, SK Daley, ME Weinand, AR Campos, ... Nature protocols 5 (7), 1265-1272, 2010 | 238 | 2010 |
Blood biomarkers for brain injury: What are we measuring? K Kawata, CY Liu, SF Merkel, SH Ramirez, RT Tierney, D Langford Neuroscience & Biobehavioral Reviews 68, 460-473, 2016 | 235 | 2016 |
Methamphetamine disrupts blood–brain barrier function by induction of oxidative stress in brain endothelial cells SH Ramirez, R Potula, S Fan, T Eidem, A Papugani, N Reichenbach, ... Journal of Cerebral Blood Flow & Metabolism 29 (12), 1933-1945, 2009 | 219 | 2009 |
HIV‐1 Tat‐mediated activation of glycogen synthase kinase‐3β contributes to Tat‐mediated neurotoxicity SB Maggirwar, N Tong, S Ramirez, HA Gelbard, S Dewhurst Journal of neurochemistry 73 (2), 578-586, 1999 | 201 | 1999 |
Angiotensin II induced cerebral microvascular inflammation and increased blood–brain barrier permeability via oxidative stress M Zhang, Y Mao, SH Ramirez, RF Tuma, T Chabrashvili Neuroscience 171 (3), 852-858, 2010 | 181 | 2010 |
Exosome-associated AAV vector as a robust and convenient neuroscience tool E Hudry, C Martin, S Gandhi, B György, DI Scheffer, D Mu, SF Merkel, ... Gene therapy 23 (4), 380-392, 2016 | 147 | 2016 |
Emerging roles of pericytes in the regulation of the neurovascular unit in health and disease J Hill, S Rom, SH Ramirez, Y Persidsky Journal of Neuroimmune Pharmacology 9, 591-605, 2014 | 136 | 2014 |
Trafficking of adeno‐associated virus vectors across a model of the blood–brain barrier; a comparative study of transcytosis and transduction using primary human brain … SF Merkel, AM Andrews, EM Lutton, D Mu, E Hudry, BT Hyman, ... Journal of neurochemistry 140 (2), 216-230, 2017 | 132 | 2017 |
HIV infects astrocytes in vivo and egresses from the brain to the periphery V Lutgen, SD Narasipura, HJ Barbian, M Richards, J Wallace, ... PLoS pathogens 16 (6), e1008381, 2020 | 131 | 2020 |
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers SH Ramirez, AM Andrews, D Paul, JS Pachter Fluids and Barriers of the CNS 15, 1-21, 2018 | 130 | 2018 |
Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5 SH Ramirez, S Fan, H Dykstra, S Rom, A Mercer, NL Reichenbach, ... PloS one 8 (2), e55972, 2013 | 124 | 2013 |
Activation of protein tyrosine kinases and matrix metalloproteinases causes blood‐brain barrier injury: Novel mechanism for neurodegeneration associated with alcohol abuse J Haorah, K Schall, SH Ramirez, Y Persidsky Glia 56 (1), 78-88, 2008 | 123 | 2008 |
Activation of peroxisome proliferator-activated receptor γ (PPARγ) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and … SH Ramirez, D Heilman, B Morsey, R Potula, J Haorah, Y Persidsky The Journal of Immunology 180 (3), 1854-1865, 2008 | 120 | 2008 |
Activation of glycogen synthase kinase 3 beta (GSK‐3β) by platelet activating factor mediates migration and cell death in cerebellar granule neurons N Tong, JF Sanchez, SB Maggirwar, SH Ramirez, H Guo, S Dewhurst, ... European Journal of Neuroscience 13 (10), 1913-1922, 2001 | 117 | 2001 |