Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions RM Savic, MO Karlsson The AAPS journal 11, 558-569, 2009 | 650 | 2009 |
Diagnosing model diagnostics MO Karlsson, RM Savic Clinical Pharmacology & Therapeutics 82 (1), 17-20, 2007 | 601 | 2007 |
Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies RM Savic, DM Jonker, T Kerbusch, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 34, 711-726, 2007 | 581 | 2007 |
Tuberculous meningitis RJ Wilkinson, U Rohlwink, UK Misra, R Van Crevel, NTH Mai, KE Dooley, ... Nature reviews neurology 13 (10), 581-598, 2017 | 469 | 2017 |
Four-month rifapentine regimens with or without moxifloxacin for tuberculosis SE Dorman, P Nahid, EV Kurbatova, PPJ Phillips, K Bryant, KE Dooley, ... New England Journal of Medicine 384 (18), 1705-1718, 2021 | 364 | 2021 |
Model evaluation of continuous data pharmacometric models: metrics and graphics THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ... CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017 | 308 | 2017 |
A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis MZ Imperial, P Nahid, PPJ Phillips, GR Davies, K Fielding, D Hanna, ... Nature medicine 24 (11), 1708-1715, 2018 | 287 | 2018 |
Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study JH Elliott, JH McMahon, CC Chang, SA Lee, W Hartogensis, N Bumpus, ... The lancet HIV 2 (12), e520-e529, 2015 | 260 | 2015 |
Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis IH Bartelink, A Lalmohamed, EML van Reij, CC Dvorak, RM Savic, ... The Lancet Haematology 3 (11), e526-e536, 2016 | 233 | 2016 |
Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption JJ Wilkins, RM Savic, MO Karlsson, G Langdon, H McIlleron, G Pillai, ... Antimicrobial agents and chemotherapy 52 (6), 2138-2148, 2008 | 196 | 2008 |
Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: a mechanistic model and tool for regimen and dose optimization N Strydom, SV Gupta, WS Fox, LE Via, H Bang, M Lee, S Eum, TS Shim, ... PLoS medicine 16 (4), e1002773, 2019 | 162 | 2019 |
Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial SE Dorman, RM Savic, S Goldberg, JE Stout, N Schluger, G Muzanyi, ... American journal of respiratory and critical care medicine 191 (3), 333-343, 2015 | 130 | 2015 |
Optimizing hydroxychloroquine dosing for patients with COVID‐19: an integrative modeling approach for effective drug repurposing M Garcia‐Cremades, BP Solans, E Hughes, JP Ernest, E Wallender, ... Clinical Pharmacology & Therapeutics 108 (2), 253-263, 2020 | 129 | 2020 |
GeneXpert MTB/Rif to diagnose tuberculous meningitis: perhaps the first test but not the last NC Bahr, S Marais, M Caws, R Van Crevel, RJ Wilkinson, JS Tyagi, ... Clinical Infectious Diseases 62 (9), 1133-1135, 2016 | 129 | 2016 |
Designing drug trials: considerations for pregnant women JS Sheffield, D Siegel, M Mirochnick, RP Heine, C Nguyen, KL Bergman, ... Clinical infectious diseases 59 (suppl_7), S437-S444, 2014 | 126 | 2014 |
Importance of drug pharmacokinetics at the site of action ML Rizk, L Zou, RM Savic, KE Dooley Clinical and translational science 10 (3), 133, 2017 | 109 | 2017 |
The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials A Vernon, K Fielding, R Savic, L Dodd, P Nahid PLoS medicine 16 (12), e1002884, 2019 | 94 | 2019 |
Population pharmacokinetics of busulfan in pediatric and young adult patients undergoing hematopoietic cell transplant: a model-based dosing algorithm for personalized therapy … JR Long-Boyle, R Savic, S Yan, I Bartelink, L Musick, D French, J Law, ... Therapeutic drug monitoring 37 (2), 236-245, 2015 | 89 | 2015 |
Effect of weight and maturation on busulfan clearance in infants and small children undergoing hematopoietic cell transplantation RM Savic, MJ Cowan, CC Dvorak, SY Pai, L Pereira, IH Bartelink, ... Biology of Blood and Marrow Transplantation 19 (11), 1608-1614, 2013 | 88 | 2013 |
Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives LE Via, R Savic, DM Weiner, MD Zimmerman, B Prideaux, SM Irwin, ... ACS infectious diseases 1 (5), 203-214, 2015 | 84 | 2015 |