| Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model W Yang, X Liu, C Song, S Ji, J Yang, Y Liu, J You, J Zhang, S Huang, ... European Journal of Medicinal Chemistry 209, 112842, 2021 | 56 | 2021 |
| Discovery of new SIRT2 inhibitors by utilizing a consensus docking/scoring strategy and structure–activity relationship analysis S Huang, C Song, X Wang, G Zhang, Y Wang, X Jiang, Q Sun, L Huang, ... Journal of Chemical Information and Modeling 57 (4), 669-679, 2017 | 42 | 2017 |
| Discovery of potent small-molecule SIRT6 activators: structure–activity relationship and anti-pancreatic ductal adenocarcinoma activity X Chen, W Sun, S Huang, H Zhang, G Lin, H Li, J Qiao, L Li, S Yang Journal of Medicinal Chemistry 63 (18), 10474-10495, 2020 | 33 | 2020 |
| Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5 … GB Li, S Ma, LL Yang, S Ji, Z Fang, G Zhang, LJ Wang, JM Zhong, ... Journal of Medicinal Chemistry 59 (18), 8293-8305, 2016 | 33 | 2016 |
| Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations S Ji, S Ma, WJ Wang, SZ Huang, T Wang, R Xiang, YG Hu, Q Chen, LL Li, ... Chemical Biology & Drug Design 89 (4), 585-598, 2017 | 30 | 2017 |
| Recent advances in modulators of circadian rhythms: an update and perspective S Huang, X Jiao, D Lu, X Pei, D Qi, Z Li Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1267-1286, 2020 | 29 | 2020 |
| Type 1 diabetes mellitus impairs diurnal oscillations in murine extraorbital lacrimal glands X Jiao, D Lu, X Pei, D Qi, S Huang, Z Song, J Gu, Z Li The Ocular Surface 18 (3), 438-452, 2020 | 27 | 2020 |
| From Lead to Drug Candidate: Optimization of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative … CH Zhang, K Chen, Y Jiao, LL Li, YP Li, RJ Zhang, MW Zheng, L Zhong, ... Journal of medicinal chemistry 59 (21), 9788-9805, 2016 | 26 | 2016 |
| Light cycle phase advance as a model for jet lag reprograms the circadian rhythms of murine extraorbital lacrimal glands S Huang, X Jiao, D Lu, X Pei, D Qi, Z Li The Ocular Surface 20, 95-114, 2021 | 25 | 2021 |
| Discovery of KDM5A inhibitors: homology modeling, virtual screening and structure–activity relationship analysis X Wu, Z Fang, B Yang, L Zhong, Q Yang, C Zhang, S Huang, R Xiang, ... Bioorganic & Medicinal Chemistry Letters 26 (9), 2284-2288, 2016 | 22 | 2016 |
| Microbial reconstitution improves aging-driven lacrimal gland circadian dysfunction X Jiao, X Pei, D Lu, D Qi, S Huang, S He, Z Li The American Journal of Pathology 191 (12), 2091-2116, 2021 | 20 | 2021 |
| Discovery of 5-(4-methylpiperazin-1-yl)-2-nitroaniline derivatives as a new class of SIRT6 inhibitors W Sun, X Chen, S Huang, W Li, C Tian, S Yang, L Li Bioorganic & Medicinal Chemistry Letters 30 (16), 127215, 2020 | 18 | 2020 |
| Sleep loss causes dysfunction in murine extraorbital lacrimal glands S Huang, H Si, J Liu, D Qi, X Pei, D Lu, S Zou, Z Li Investigative Ophthalmology & Visual Science 63 (6), 19-19, 2022 | 17 | 2022 |
| Synthesis and evaluation of novel thiazole‐based derivatives as selective inhibitors of DNA‐binding domain of the androgen receptor R Xu, Y Tian, S Huang, J Yu, Y Deng, M Zhan, T Zhang, F Wang, L Zhao, ... Chemical Biology & Drug Design 91 (1), 172-180, 2018 | 16 | 2018 |
| Structural optimization and structure-activity relationship studies of N-phenyl-7, 8-dihydro-6H-pyrimido [5, 4-b][1, 4] oxazin-4-amine derivatives as a new class of inhibitors … J Yang, K Chen, G Zhang, QY Yang, YS Li, SZ Huang, YL Wang, W Yang, ... European Journal of Medicinal Chemistry 143, 1148-1164, 2018 | 16 | 2018 |
| How to face COVID-19 in ophthalmology practice X Pei, X Jiao, D Lu, D Qi, S Huang, Z Li Medical hypothesis discovery and innovation in ophthalmology 9 (3), 164-171, 2020 | 15 | 2020 |
| High-fat nutritional challenge reshapes circadian signatures in murine extraorbital lacrimal glands S Zou, X Jiao, J Liu, D Qi, X Pei, D Lu, S Huang, Z Li Investigative Ophthalmology & Visual Science 63 (5), 23-23, 2022 | 12 | 2022 |
| Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7 X Zhou, X Yang, S Huang, G Lin, K Lei, Q Wang, W Lin, H Li, X Qi, ... Advanced Science, 2308786, 2024 | 11 | 2024 |
| Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti–Acute Myeloid Leukemia Efficacy In Vitro and In Vivo ZX Cao, Y Wen, JL He, SZ Huang, F Gao, CJ Guo, QQ Liu, SW Zheng, ... Molecular Pharmacology 96 (5), 589-599, 2019 | 11 | 2019 |
| Mechanisms of extraorbital lacrimal gland aging in mice: an integrative analysis of the temporal transcriptome J Liu, H Si, D Huang, D Lu, S Zou, D Qi, X Pei, S Huang, Z Li Investigative Ophthalmology & Visual Science 64 (12), 18-18, 2023 | 9 | 2023 |
