Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals C Chen, D Pung, V Leong, V Hebbar, G Shen, S Nair, W Li, ANT Kong Free Radical Biology and Medicine 37 (10), 1578-1590, 2004 | 350 | 2004 |
Regulation of Nrf2 transactivation domain activity: the differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB … G Shen, V Hebbar, S Nair, C Xu, W Li, W Lin, YS Keum, J Han, MA Gallo, ... Journal of Biological Chemistry 279 (22), 23052-23060, 2004 | 246 | 2004 |
ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells C Xu, G Shen, X Yuan, J Kim, A Gopalkrishnan, YS Keum, S Nair, ... Carcinogenesis 27 (3), 437-445, 2006 | 206 | 2006 |
Natural dietary anti‐cancer chemopreventive compounds: redox‐mediated differential signaling mechanisms in cytoprotection of normal cells versus cytotoxicity in tumor cells 1 S Nair, W Li, ANT KONG Acta Pharmacologica Sinica 28 (4), 459-472, 2007 | 199 | 2007 |
Modulation of nuclear factor E2-related factor 2–mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin G Shen, C Xu, R Hu, MR Jain, A Gopalkrishnan, S Nair, MT Huang, ... Molecular cancer therapeutics 5 (1), 39-51, 2006 | 196 | 2006 |
Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in Apc Min/+ mouse G Shen, TO Khor, R Hu, S Yu, S Nair, CT Ho, BS Reddy, MT Huang, ... Cancer research 67 (20), 9937-9944, 2007 | 192 | 2007 |
Comparison of (−)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (−/−) mice G Shen, C Xu, R Hu, MR Jain, S Nair, W Lin, CS Yang, JY Chan, ... Pharmaceutical research 22, 1805-1820, 2005 | 190 | 2005 |
Regulatory potential for concerted modulation of Nrf2-and Nfkb1-mediated gene expression in inflammation and carcinogenesis S Nair, ST Doh, JY Chan, AN Kong, L Cai British journal of cancer 99 (12), 2070-2082, 2008 | 175 | 2008 |
Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane BR Kim, R Hu, YS Keum, V Hebbar, G Shen, SS Nair, ANT Kong Cancer research 63 (21), 7520-7525, 2003 | 154 | 2003 |
γ‐Tocopherol‐enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice A Barve, TO Khor, S Nair, K Reuhl, N Suh, B Reddy, H Newmark, ... International Journal of Cancer 124 (7), 1693-1699, 2009 | 153 | 2009 |
Modulation of activator protein-1 (AP-1) and MAPK pathway by flavonoids in human prostate cancer PC3 cells A Gopalakrishnan, CJ Xu, SS Nair, C Chen, V Hebbar, ANT Kong Archives of pharmacal research 29, 633-644, 2006 | 103 | 2006 |
Regulation of Nrf2-and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate … S Nair, A Barve, TO Khor, G Shen, W Lin, JY Chan, L Cai, AN Kong Acta Pharmacologica Sinica 31 (9), 1223-1240, 2010 | 99 | 2010 |
Synergistic effects of a combination of dietary factors sulforaphane and (−) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells S Nair, V Hebbar, G Shen, A Gopalakrishnan, TO Khor, S Yu, C Xu, ... Pharmaceutical research 25, 387-399, 2008 | 89 | 2008 |
Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression A Prawan, YS Keum, TO Khor, S Yu, S Nair, W Li, L Hu, ANT Kong Pharmaceutical Research 25, 836-844, 2008 | 81 | 2008 |
Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice S Nair, C Xu, G Shen, V Hebbar, A Gopalakrishnan, R Hu, MR Jain, W Lin, ... Pharmaceutical research 23, 2621-2637, 2006 | 79 | 2006 |
Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice TO Khor, R Hu, G Shen, WS Jeong, V Hebbar, C Chen, C Xu, S Nair, ... Biopharmaceutics & drug disposition 27 (9), 407-420, 2006 | 77 | 2006 |
Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice S Nair, C Xu, G Shen, V Hebbar, A Gopalakrishnan, R Hu, MR Jain, ... Toxicology letters 168 (1), 21-39, 2007 | 76 | 2007 |
Current insights into epigenetics, noncoding RNA interactome and clinical pharmacokinetics of dietary polyphenols in cancer chemoprevention D Shah, M Gandhi, A Kumar, N Cruz-Martins, R Sharma, S Nair Critical reviews in food science and nutrition 63 (12), 1755-1791, 2023 | 48 | 2023 |
Pharmacogenomic profile of soy isoflavone concentrate in the prostate of Nrf2 deficient and wild‐type mice A Barve, TO Khor, S Nair, W Lin, S Yu, MR Jain, JY Chan, AN Kong Journal of pharmaceutical sciences 97 (10), 4528-4545, 2008 | 47 | 2008 |
Emerging roles for modulation of microRNA signatures in cancer chemoprevention K Neelakandan, P Babu, S Nair Current cancer drug targets 12 (6), 716-740, 2012 | 46 | 2012 |