Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, SM Meng, ... Nature Biomedical Engineering 5 (6), 600-612, 2021 | 258* | 2021 |
High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis DM Mason, CR Weber, C Parola, SM Meng, V Greiff, WJ Kelton, ... Nucleic acids research 46 (14), 7436-7449, 2018 | 82 | 2018 |
Convergent selection in antibody repertoires is revealed by deep learning S Friedensohn, D Neumeier, TA Khan, L Csepregi, C Parola, ... BioRxiv, 2020.02. 25.965673, 2020 | 45 | 2020 |
A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients F Bieberich, R Vazquez-Lombardi, A Yermanos, RA Ehling, DM Mason, ... Frontiers in immunology 12, 701085, 2021 | 41 | 2021 |
Antibody discovery and engineering by enhanced CRISPR-Cas9 integration of variable gene cassette libraries in mammalian cells C Parola, D Neumeier, S Friedensohn, L Csepregi, M Di Tacchio, ... MAbs 11 (8), 1367-1380, 2019 | 29 | 2019 |
SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ... Cell reports 38 (3), 2022 | 21* | 2022 |
Genome engineering of hybridomas to generate stable cell lines for antibody expression C Parola, DM Mason, A Zingg, D Neumeier, ST Reddy Recombinant Protein Expression in Mammalian Cells: Methods and Protocols, 79-111, 2018 | 9 | 2018 |
Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning. Nat Biomed Eng. 2021; 5 (6): 600–12 DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, SM Meng, ... | 7 | |
Systems and methods to classify antibodies D Mason, S Friedensohn, C Weber, S Reddy US Patent App. 17/439,374, 2022 | 6 | 2022 |
Initial characterisation of ELISA assays and the immune response of the clinically correlated SARS-CoV-2 biobank SERO-BL-COVID-19 collected during the pandemic onset in Switzerland HM Kaltenbach, F Rudolf, J Linnik, J Deichmann, T Ruf, R Altamura, ... | 5 | 2020 |
Initial characterisation of commercially available ELISA tests and the immune response of the clinically correlated SARS-CoV-2 biobank “SERO-BL-COVID-19” collected during the … HM Kaltenbach, F Rudolf, J Linnik, J Deichmann, T Ruf, R Altamura, ... medRxiv, 2020.07. 05.20145888, 2020 | 1 | 2020 |
Mammalian cell line for protein production and library generation S Reddy, W Kelton, C Parola, D Mason, M Pogson US Patent App. 18/329,296, 2023 | | 2023 |
Mammalian cell line for protein production and library generation S Reddy, W Kelton, C Parola, D Mason, M Pogson US Patent 11,802,281, 2023 | | 2023 |
Antibody engineering by combining genome editing, deep sequencing, and deep learning D Mason ETH Zurich, 2020 | | 2020 |