An abnormal mitochondrial–hypoxia inducible factor-1α–Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities … S Bonnet, ED Michelakis, CJ Porter, MA Andrade-Navarro, B Thébaud, ... Circulation 113 (22), 2630-2641, 2006 | 668 | 2006 |
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility J Nagendran, SL Archer, D Soliman, V Gurtu, R Moudgil, A Haromy, ... Circulation 116 (3), 238-248, 2007 | 614 | 2007 |
Hypoxic pulmonary vasoconstriction R Moudgil, ED Michelakis, SL Archer Journal of applied physiology 98 (1), 390-403, 2005 | 603 | 2005 |
Cardiovascular complications of cancer therapy: best practices in diagnosis, prevention, and management: part 1 HM Chang, R Moudgil, T Scarabelli, TM Okwuosa, ETH Yeh Journal of the American College of Cardiology 70 (20), 2536-2551, 2017 | 591 | 2017 |
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated … ED Michelakis, MS McMurtry, XC Wu, JRB Dyck, R Moudgil, TA Hopkins, ... Circulation 105 (2), 244-250, 2002 | 459 | 2002 |
In Vivo Gene Transfer of the O2-Sensitive Potassium Channel Kv1.5 Reduces Pulmonary Hypertension and Restores Hypoxic Pulmonary Vasoconstriction in … ZI Pozeg, ED Michelakis, MS McMurtry, B Thébaud, XC Wu, JRB Dyck, ... Circulation 107 (15), 2037-2044, 2003 | 340 | 2003 |
The Role of K+ Channels in Determining Pulmonary Vascular Tone, Oxygen Sensing, Cell Proliferation, and Apoptosis: Implications in Hypoxic Pulmonary … R Moudgil, ED Michelakis, SL Archer Microcirculation 13 (8), 615-632, 2006 | 232 | 2006 |
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen … H Kajimoto, K Hashimoto, SN Bonnet, A Haromy, G Harry, R Moudgil, ... Circulation 115 (13), 1777-1788, 2007 | 184 | 2007 |
Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus … B Thébaud, ED Michelakis, XC Wu, R Moudgil, M Kuzyk, JRB Dyck, ... Circulation 110 (11), 1372-1379, 2004 | 130 | 2004 |
The neurovascular mechanism of clitoral erection: nitric oxide and cGMP‐stimulated activation of BKCa channels FS Gragasin, ED Michelakis, A Hogan, R Moudgil, K Hashimoto, X Wu, ... The FASEB journal 18 (12), 1382-1391, 2004 | 112 | 2004 |
Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension MS McMurtry, R Moudgil, K Hashimoto, S Bonnet, ED Michelakis, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (4 …, 2007 | 95 | 2007 |
Mechanisms of cardiotoxicity of cancer chemotherapeutic agents: cardiomyopathy and beyond R Moudgil, ETH Yeh Canadian Journal of Cardiology 32 (7), 863-870. e5, 2016 | 93 | 2016 |
O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide SL Archer, XC Wu, B Thebaud, R Moudgil, K Hashimoto, ED Michelakis Walter de Gruyter 385 (3-4), 205-216, 2004 | 76 | 2004 |
Progressive and reversible conduction disease with checkpoint inhibitors N Reddy, R Moudgil, JC Lopez-Mattei, K Karimzad, EN Mouhayar, ... Canadian Journal of Cardiology 33 (10), 1335. e13-1335. e15, 2017 | 54 | 2017 |
Postischemic apoptosis and functional recovery after angiotensin II type 1 receptor blockade in isolated working rat hearts R Moudgil, V Menon, Y Xu, S Musat-Marcu, D Kumar, BI Jugdutt Journal of hypertension 19 (6), 1121-1129, 2001 | 54 | 2001 |
Machine learning–based risk assessment for cancer therapy–related cardiac dysfunction in 4300 longitudinal oncology patients Y Zhou, Y Hou, M Hussain, SA Brown, T Budd, WHW Tang, J Abraham, ... Journal of the American Heart Association 9 (23), e019628, 2020 | 48 | 2020 |
Depression in heart failure R Moudgil, H Haddad Current Opinion in Cardiology 28 (2), 249-258, 2013 | 43 | 2013 |
Cardioprotection induced by AT1R blockade after reperfused myocardial infarction: Association with regional increase in AT2R, IP3R and PKCε proteins and cGMP BI Jugdutt, Y Xu, M Balghith, R Moudgil, V Menon Journal of Cardiovascular Pharmacology and Therapeutics 5 (4), 301-311, 2000 | 36 | 2000 |
A Central Role for Oxygen‐Sensitive K+ Channels and Mitochondria in the Specialized Oxygen‐Sensing System SL Archer, ED Michelakis, B Thébaud, S Bonnet, R Moudgil, XC Wu, ... Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium …, 2006 | 32 | 2006 |
Gene transfer and metabolic modulators as new therapies for pulmonary hypertension: increasing expression and activity of potassium channels in rat and human models ED Michelakis, JRB Dyck, MS McMurtry, S Wang, XC Wu, R Moudgil, ... Hypoxia: From Genes to the Bedside, 401-418, 2001 | 32 | 2001 |