Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity K Movahedi, M Guilliams, J Van den Bossche, R Van den Bergh, ... Blood, The Journal of the American Society of Hematology 111 (8), 4233-4244, 2008 | 1529 | 2008 |
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes K Movahedi, D Laoui, C Gysemans, M Baeten, G Stangé, ... Cancer research 70 (14), 5728-5739, 2010 | 1272 | 2010 |
Macrophage immunometabolism: where are we (going)? J Van den Bossche, LA O’Neill, D Menon Trends in immunology 38 (6), 395-406, 2017 | 885 | 2017 |
Mitochondrial dysfunction prevents repolarization of inflammatory macrophages J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ... Cell reports 17 (3), 684-696, 2016 | 719 | 2016 |
Oxidized phospholipids on lipoprotein (a) elicit arterial wall inflammation and an inflammatory monocyte response in humans FM van der Valk, S Bekkering, J Kroon, C Yeang, J Van den Bossche, ... Circulation 134 (8), 611-624, 2016 | 513 | 2016 |
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions D Laoui, K Movahedi, E Van Overmeire, J Van den Bossche, E Schouppe, ... International Journal of Developmental Biology 55 (7-8-9), 861-867, 2011 | 371 | 2011 |
Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis J Van den Bossche, J Baardman, MPJ de Winther JoVE (Journal of Visualized Experiments), e53424, 2015 | 302 | 2015 |
Single-cell metabolic profiling of human cytotoxic T cells FJ Hartmann, D Mrdjen, E McCaffrey, DR Glass, NF Greenwald, ... Nature biotechnology 39 (2), 186-197, 2021 | 230 | 2021 |
Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs J Van den Bossche, B Malissen, A Mantovani, P De Baetselier, ... Blood, The Journal of the American Society of Hematology 119 (7), 1623-1633, 2012 | 188 | 2012 |
PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia SJ Bernelot Moens, AE Neele, J Kroon, FM Van Der Valk, ... European heart journal 38 (20), 1584-1593, 2017 | 173 | 2017 |
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions MA Hoeksema, MJJ Gijbels, J Van den Bossche, S van der Velden, ... EMBO molecular medicine 6 (9), 1124-1132, 2014 | 166 | 2014 |
A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia J Baardman, SGS Verberk, KHM Prange, M van Weeghel, ... Cell reports 25 (8), 2044-2052. e5, 2018 | 165 | 2018 |
Metabolic alterations in aging macrophages: ingredients for inflammaging? AA Van Beek, J Van den Bossche, PG Mastroberardino, MPJ De Winther, ... Trends in immunology 40 (2), 113-127, 2019 | 164 | 2019 |
Immunometabolism in the single-cell era MN Artyomov, J Van den Bossche Cell metabolism 32 (5), 710-725, 2020 | 142 | 2020 |
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes J Van den Bossche, P Bogaert, J Van Hengel, CJ Guérin, G Berx, ... Blood, The Journal of the American Society of Hematology 114 (21), 4664-4674, 2009 | 136 | 2009 |
Pivotal advance: arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced … J Van den Bossche, WH Lamers, ES Koehler, JMC Geuns, L Alhonen, ... Journal of leukocyte biology 91 (5), 685-699, 2012 | 135 | 2012 |
Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site D Laoui, E Van Overmeire, K Movahedi, J Van den Bossche, E Schouppe, ... Immunobiology 216 (11), 1192-1202, 2011 | 122 | 2011 |
Nuclear receptor Nur77 limits the macrophage inflammatory response through transcriptional reprogramming of mitochondrial metabolism DS Koenis, L Medzikovic, PB van Loenen, M van Weeghel, S Huveneers, ... Cell reports 24 (8), 2127-2140. e7, 2018 | 120 | 2018 |
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality MR Boon, SAA van den Berg, Y Wang, J van den Bossche, ... PLoS One 8 (9), e74083, 2013 | 112 | 2013 |
Macrophage polarization: the epigenetic point of view J Van den Bossche, AE Neele, MA Hoeksema, MPJ De Winther Current opinion in lipidology 25 (5), 367-373, 2014 | 102 | 2014 |