| PD-1 blockade in tumors with mismatch-repair deficiency DT Le, JN Uram, H Wang, BR Bartlett, H Kemberling, AD Eyring, ... New England Journal of Medicine 372 (26), 2509-2520, 2015 | 9599 | 2015 |
| Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ... Science 357 (6349), 409-413, 2017 | 6118 | 2017 |
| A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination … CR Boland, SN Thibodeau, SR Hamilton, D Sidransky, JR Eshleman, ... Cancer research 58 (22), 5248-5257, 1998 | 5119 | 1998 |
| Core signaling pathways in human pancreatic cancers revealed by global genomic analyses S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1801-1806, 2008 | 4645 | 2008 |
| Genomic analyses identify molecular subtypes of pancreatic cancer P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ... Nature 531 (7592), 47-52, 2016 | 3218 | 2016 |
| Distant metastasis occurs late during the genetic evolution of pancreatic cancer S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ... Nature 467 (7319), 1114-1117, 2010 | 2913 | 2010 |
| Whole genomes redefine the mutational landscape of pancreatic cancer N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ... Nature 518 (7540), 495-501, 2015 | 2647 | 2015 |
| Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ... Nature 491 (7424), 399-405, 2012 | 2200 | 2012 |
| Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours DM Berman, SS Karhadkar, A Maitra, R Montes de Oca, MR Gerstenblith, ... Nature 425 (6960), 846-851, 2003 | 1652 | 2003 |
| DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ... Journal of clinical oncology 27 (11), 1806-1813, 2009 | 1175 | 2009 |
| Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ... Science 324 (5924), 217-217, 2009 | 1032 | 2009 |
| Microsatellite instability as a biomarker for PD-1 blockade JC Dudley, MT Lin, DT Le, JR Eshleman Clinical Cancer Research 22 (4), 813-820, 2016 | 874 | 2016 |
| Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development J Wu, H Matthaei, A Maitra, M Dal Molin, LD Wood, JR Eshleman, ... Science translational medicine 3 (92), 92ra66-92ra66, 2011 | 855 | 2011 |
| Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways J Wu, Y Jiao, M Dal Molin, A Maitra, RF De Wilde, LD Wood, JR Eshleman, ... Proceedings of the National Academy of Sciences 108 (52), 21188-21193, 2011 | 665 | 2011 |
| ATM Mutations in Patients with Hereditary Pancreatic Cancer NJ Roberts, Y Jiao, J Yu, L Kopelovich, GM Petersen, ML Bondy, ... Cancer discovery 2 (1), 41-46, 2012 | 581 | 2012 |
| Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications AC Tsiatis, A Norris-Kirby, RG Rich, MJ Hafez, CD Gocke, JR Eshleman, ... The Journal of Molecular Diagnostics 12 (4), 425-432, 2010 | 577 | 2010 |
| Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays CA Iacobuzio-Donahue, A Maitra, M Olsen, AW Lowe, NT Van Heek, ... The American journal of pathology 162 (4), 1151-1162, 2003 | 571 | 2003 |
| Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita M Armanios, JL Chen, YPC Chang, RA Brodsky, A Hawkins, CA Griffin, ... Proceedings of the National Academy of Sciences 102 (44), 15960-15964, 2005 | 560 | 2005 |
| An in vivo platform for translational drug development in pancreatic cancer B Rubio-Viqueira, A Jimeno, G Cusatis, X Zhang, C Iacobuzio-Donahue, ... Clinical cancer research 12 (15), 4652-4661, 2006 | 492 | 2006 |
| Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients M Sausen, J Phallen, V Adleff, S Jones, RJ Leary, MT Barrett, ... Nature communications 6 (1), 7686, 2015 | 471 | 2015 |
