PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells B Rah, R Rasool, D Nayak, SK Yousuf, D Mukherjee, LD Kumar, ... Autophagy 11 (2), 314-331, 2015 | 91 | 2015 |
4′-Demethyl-deoxypodophyllotoxin glucoside isolated from Podophyllum hexandrum exhibits potential anticancer activities by altering Chk-2 signaling pathway in MCF-7 breast … MK Zilla, D Nayak, H Amin, Y Nalli, B Rah, S Chakraborty, S Kitchlu, ... Chemico-Biological Interactions 224, 100-107, 2014 | 49 | 2014 |
Design and synthesis of antitumor heck-coupled Sclareol analogues: modulation of BH3 family members by SS-12 in autophagy and apoptotic cell death B Rah, SH Lone, RU Rasool, S Farooq, D Nayak, NA Chikan, ... Journal of Medicinal Chemistry 58 (8), 3432-3444, 2015 | 47 | 2015 |
Par‐4 dependent modulation of cellular β‐catenin by medicinal plant natural product derivative 3‐azido Withaferin A H Amin, D Nayak, R ur Rasool, S Chakraborty, A Kumar, K Yousuf, ... Molecular Carcinogenesis 55 (5), 864-881, 2016 | 44 | 2016 |
A convergent synthesis of alkyne–azide cycloaddition derivatives of 4-α, β-2-propyne podophyllotoxin depicting potent cytotoxic activity MK Zilla, D Nayak, RA Vishwakarma, PR Sharma, A Goswami, A Ali European Journal of Medicinal Chemistry 77, 47-55, 2014 | 44 | 2014 |
Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells D Nayak, A Kumar, S Chakraborty, H Amin, A Katoch, V Gopinath, ... Cell Death & Differentiation 24 (7), 1275-1287, 2017 | 42 | 2017 |
Integration of EMT and cellular survival instincts in reprogramming of programmed cell death to anastasis S Chakraborty, KB Mir, ND Seligson, D Nayak, R Kumar, A Goswami Cancer and Metastasis Reviews 39, 553-566, 2020 | 39 | 2020 |
Development and mechanistic insight into enhanced cytotoxic potential of hyaluronic acid conjugated nanoparticles in CD44 overexpressing cancer cells A Saneja, D Nayak, M Srinivas, A Kumar, V Khare, A Katoch, A Goswami, ... European Journal of Pharmaceutical Sciences 97, 79-91, 2017 | 38 | 2017 |
Dual role of Par‐4 in abrogation of EMT and switching on mesenchymal to epithelial transition (MET) in metastatic pancreatic cancer cells A Katoch, S Suklabaidya, S Chakraborty, D Nayak, RU Rasool, D Sharma, ... Molecular carcinogenesis 57 (9), 1102-1115, 2018 | 37 | 2018 |
EMT-induced gemcitabine resistance in pancreatic cancer involves the functional loss of equilibrative nucleoside transporter 1 B Weadick, D Nayak, AK Persaud, SW Hung, R Raj, MJ Campbell, ... Molecular cancer therapeutics 20 (2), 410-422, 2021 | 36 | 2021 |
Vimentin activation in early apoptotic cancer cells errands survival pathways during DNA damage inducer CPT treatment in colon carcinoma model S Chakraborty, A Kumar, MM Faheem, A Katoch, A Kumar, VL Jamwal, ... Cell Death & Disease 10 (6), 467, 2019 | 36 | 2019 |
A new cytotoxic quinolone alkaloid and a pentacyclic steroidal glycoside from the stem bark of Crataeva nurvala: Study of anti-proliferative and apoptosis inducing property S Sinha, P Mishra, H Amin, B Rah, D Nayak, A Goswami, N Kumar, ... European journal of medicinal chemistry 60, 490-496, 2013 | 36 | 2013 |
Assessment of microtubule depolymerization property of flavonoids isolated from Tanacetum gracile in breast cancer cells by biochemical and molecular docking approach S Sinha, H Amin, D Nayak, M Bhatnagar, P Kacker, S Chakraborty, ... Chemico-biological interactions 239, 1-11, 2015 | 32 | 2015 |
Preparation, characterization and toxicological investigation of copper loaded chitosan nanoparticles in human embryonic kidney HEK-293 cells D Arora, V Dhanwal, D Nayak, A Saneja, H Amin, R ur Rasool, PN Gupta, ... Materials Science and Engineering: C 61, 227-234, 2016 | 29 | 2016 |
Cristacarpin promotes ER stress-mediated ROS generation leading to premature senescence by activation of p21waf-1 S Chakraborty, RU Rasool, S Kumar, D Nayak, B Rah, A Katoch, H Amin, ... Age 38, 1-14, 2016 | 28 | 2016 |
Inhibition of Invasion in Pancreatic Cancer Cells by Conjugate of EPA with β3,3-Pip-OH via PI3K/Akt/NF-kB Pathway H Amin, NA Wani, S Farooq, D Nayak, S Chakraborty, S Shankar, ... ACS Medicinal Chemistry Letters 6 (10), 1071-1074, 2015 | 25 | 2015 |
Indolylkojyl methane analogue IKM5 potentially inhibits invasion of breast cancer cells via attenuation of GRP78 D Nayak, A Katoch, D Sharma, MM Faheem, S Chakraborty, PK Sahu, ... Breast cancer research and treatment 177, 307-323, 2019 | 24 | 2019 |
Dual modulation of Ras-Mnk and PI3K-AKT-mTOR pathways: a novel c-FLIP inhibitory mechanism of 3-AWA mediated translational attenuation through dephosphorylation of eIF4E R Ur Rasool, B Rah, H Amin, D Nayak, S Chakraborty, A Rawoof, ... Scientific Reports 6 (1), 18800, 2016 | 24 | 2016 |
Natural podophyllotoxin analog 4DPG attenuates EMT and colorectal cancer progression via activation of checkpoint kinase 2 A Katoch, D Nayak, MM Faheem, A Kumar, PK Sahu, AP Gupta, ... Cell Death Discovery 7 (1), 25, 2021 | 21 | 2021 |
Regiospecific synthesis of ring a fused withaferin a isoxazoline analogues: Induction of premature senescence by W-2b in proliferating cancer cells F Rasool, D Nayak, A Katoch, MM Faheem, SK Yousuf, N Hussain, ... Scientific Reports 7 (1), 13749, 2017 | 21 | 2017 |