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Ashleigh Burke
Ashleigh Burke
Scripps Institution of Oceanography
在 ucsd.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Design and evolution of an enzyme with a non-canonical organocatalytic mechanism
AJ Burke, SL Lovelock, A Frese, R Crawshaw, M Ortmayer, M Dunstan, ...
Nature 570 (7760), 219-223, 2019
1512019
Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction
R Crawshaw, AE Crossley, L Johannissen, AJ Burke, S Hay, C Levy, ...
Nature chemistry 14 (3), 313-320, 2022
642022
Enzymes with noncanonical amino acids
J Zhao, AJ Burke, AP Green
Current Opinion in Chemical Biology 55, 136-144, 2020
532020
An engineered cytidine deaminase for biocatalytic production of a key intermediate of the Covid-19 antiviral molnupiravir
AJ Burke, WR Birmingham, Y Zhuo, TW Thorpe, B Zucoloto da Costa, ...
Journal of the American Chemical Society 144 (9), 3761-3765, 2022
412022
Biocatalysis: landmark discoveries and applications in chemical synthesis
A O’Connell, A Barry, AJ Burke, AE Hutton, EL Bell, AP Green, E O’Reilly
Chemical Society Reviews, 2024
212024
Multicomponent synthesis of the SARS-CoV-2 main protease inhibitor nirmatrelvir
HD Preschel, RT Otte, Y Zhuo, RE Ruscoe, AJ Burke, R Kellerhals, ...
The Journal of organic chemistry 88 (17), 12565-12571, 2023
112023
Strategies for designing biocatalysts with new functions
EL Bell, AE Hutton, AJ Burke, A O’Connell, A Barry, E O’Reilly, AP Green
Chemical Society Reviews, 2024
92024
Engineered Biocatalysts for Enantioselective Reductive Aminations of Cyclic Secondary Amines
AJ Burke, TM Lister, JR Marshall, MJB Brown, R Lloyd, AP Green, ...
ChemCatChem 15 (11), e202300256, 2023
52023
A biocatalytic approach to a key intermediate for the synthesis of the COVID-19 experimental drug Molnupiravir
A Burke, W Birmingham, Y Zhuo, C BZd, R Crawshaw, T Thorpe, I Rowles, ...
52021
Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues
CJ Taylor, FJ Hardy, AJ Burke, RM Bednar, RA Mehl, AP Green, ...
Protein Science 32 (5), e4640, 2023
42023
Chemoenzymatic multicomponent synthesis of nirmatrelvir
HD Preschel, RT Otte, Y Zhuo, RE Ruscoe, AJ Burke, R Cowan, B Horst, ...
32022
Engineering a Cytidine Aminotransferase for Biocatalytic Production of the Antiviral Molnupiravir
A Burke, W Birmingham, Y Zhuo, BZ da Costa, R Crawshaw, T Thorpe, ...
12021
Engineered Biocatalyst Permits Enantioselective Morita–Baylis–Hillman Reaction
R CRAWSHAW, AE CROSSLEY, L JOHANNISSEN, AJ BURKE, S HAY, ...
Science 374, 1612-1616, 2021
2021
Engineering enzymes with non-canonical active site functionality
SL Lovelock, AJ Burke, R Crawshaw, M Ortmayer, M Dunstan, C Levy, ...
2019
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