| Irreversible inhibitors of serine, cysteine, and threonine proteases JC Powers, JL Asgian, ÖD Ekici, KE James Chemical reviews 102 (12), 4639-4750, 2002 | 1361 | 2002 |
| Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site. K Nakajima, JC Powers, BM Ashe, M Zimmerman Journal of Biological Chemistry 254 (10), 4027-4032, 1979 | 761 | 1979 |
| Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. L Shi, CM Kam, JC Powers, R Aebersold, AH Greenberg The Journal of experimental medicine 176 (6), 1521-1529, 1992 | 546 | 1992 |
| Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors W Bode, E Meyer Jr, JC Powers Biochemistry 28 (5), 1951-1963, 1989 | 539 | 1989 |
| Sensitive substrates for human leukocyte and porcine pancreatic elastase: a study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine … MJ Castillo, K Nakajima, M Zimmerman, JC Powers Analytical biochemistry 99 (1), 53-64, 1979 | 338 | 1979 |
| Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum S Arastu-Kapur, EL Ponder, UP Fonović, S Yeoh, F Yuan, M Fonović, ... Nature chemical biology 4 (3), 203-213, 2008 | 318 | 2008 |
| Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G Inhibition with peptide chloromethyl ketones JC Powers, BF Gupton, AD Harley, N Nishino, RJ Whitley Biochimica et Biophysica Acta (BBA)-Enzymology 485 (1), 156-166, 1977 | 295 | 1977 |
| Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins S Odake, CM Kam, L Narasimhan, M Poe, JT Blake, O Krahenbuhl, ... Biochemistry 30 (8), 2217-2227, 1991 | 283 | 1991 |
| Reaction of serine proteases with substituted isocoumarins: discovery of 3, 4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor JW Harper, K Hemmi, JC Powers Biochemistry 24 (8), 1831-1841, 1985 | 281 | 1985 |
| Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex A Vinitsky, C Michaud, JC Powers, M Orlowski Biochemistry 31 (39), 9421-9428, 1992 | 278 | 1992 |
| Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration. RT Bartus, NJ Hayward, PJ Elliott, SD Sawyer, KL Baker, RL Dean, ... Stroke 25 (11), 2265-2270, 1994 | 273 | 1994 |
| Irreversible inhibition of serine proteases by peptide derivatives of (. alpha.-aminoalkyl) phosphonate diphenyl esters J Oleksyszyn, JC Powers Biochemistry 30 (2), 485-493, 1991 | 255 | 1991 |
| X‐ray Structures of Human Neutrophil Collagenase Complexed with Peptide Hydroxamate and Peptide Thiol Inhibitors: Implications for Substrate Binding and Rational Drug Design F Grams, P Reinemer, JC Powers, T Kleine, M Pieper, H Tschesche, ... European journal of biochemistry 228 (3), 830-841, 1995 | 243 | 1995 |
| Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors CM Kam, D Hudig, JC Powers Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000 | 241 | 2000 |
| Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors DM Segal, JC Powers, GH Cohen, DR Davies, PE Wilcox Biochemistry 10 (20), 3728-3738, 1971 | 228 | 1971 |
| X-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN JD Robertus, RA Alden, JJ Birktoft, J Kraut, JC Powers, PE Wilcox Biochemistry 11 (13), 2439-2449, 1972 | 223 | 1972 |
| Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide … JC Powers, T Tanaka, JW Harper, Y Minematsu, L Barker, D Lincoln, ... Biochemistry 24 (8), 2048-2058, 1985 | 208 | 1985 |
| Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide TW Lee, MM Cherney, C Huitema, J Liu, KE James, JC Powers, LD Eltis, ... Journal of molecular biology 353 (5), 1137-1151, 2005 | 204 | 2005 |
| Novel peptidyl α-keto amide inhibitors of calpains and other cysteine proteases Z Li, AC Ortega-Vilain, GS Patil, DL Chu, JE Foreman, DD Eveleth, ... Journal of medicinal chemistry 39 (20), 4089-4098, 1996 | 196 | 1996 |
| Inhibition of thermolysin and carboxypeptidase A by phosphoramidates CM Kam, N Nishino, JC Powers Biochemistry 18 (14), 3032-3038, 1979 | 185 | 1979 |
