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Alex Clark
Alex Clark
Lecturer in Neuroscience, Queen Mary University
在 qmul.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
The role of voltage-gated sodium channels in pain signaling
DL Bennett, AJ Clark, J Huang, SG Waxman, SD Dib-Hajj
Physiological reviews 99 (2), 1079-1151, 2019
5292019
Defining the functional role of NaV1. 7 in human nociception
LA McDermott, GA Weir, AC Themistocleous, AR Segerdahl, I Blesneac, ...
Neuron 101 (5), 905-919. e8, 2019
1742019
Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability
JM Dawes, GA Weir, SJ Middleton, R Patel, KI Chisholm, P Pettingill, ...
Neuron 97 (4), 806-822. e10, 2018
1552018
Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination
Clark AJ, Kaller MS, Galino J, Willison HJ, Rinaldi S, Bennett DL
Brain 140 (4), 898-913, 2017
1082017
Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source
GA Weir, SJ Middleton, AJ Clark, T Daniel, N Khovanov, SB McMahon, ...
Brain 140 (10), 2570-2585, 2017
662017
Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury
G Baskozos, JM Dawes, JS Austin, A Antunes-Martins, L McDermott, ...
Pain 160 (2), 463-485, 2019
522019
Molecular and cellular correlates of human nerve regeneration: ADCYAP1/PACAP enhance nerve outgrowth
G Baskozos, O Sandy-Hindmarch, AJ Clark, K Windsor, P Karlsson, ...
Brain 143 (7), 2009-2026, 2020
482020
Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro
ER Wilson, U Kugathasan, AY Abramov, AJ Clark, DLH Bennett, ...
Neurobiology of Disease 117, 1-14, 2018
452018
An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions
AJ Clark, U Kugathasan, G Baskozos, DA Priestman, N Fugger, MA Lone, ...
Cell Reports Medicine 2 (7), 2021
202021
Functional imaging in microfluidic chambers reveals sensory neuron sensitivity is differentially regulated between neuronal regions
AJ Clark, G Menendez, M AlQatari, N Patel, E Arstad, G Schiavo, ...
Pain 159 (7), 1413-1425, 2018
112018
A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons
J Perez-Sanchez, SJ Middleton, LA Pattison, H Hilton, ...
Science translational medicine 15 (716), eadh3839, 2023
52023
Establishing myelinating cocultures using human iPSC-derived sensory neurons to investigate axonal degeneration and demyelination
AJ Clark
Axon Degeneration: Methods and Protocols, 111-129, 2020
42020
Building a systematic online living evidence summary of COVID-19 research
K Hair, ES Sena, E Wilson, G Currie, M Macleod, Z Bahor, C Sena, ...
Journal of EAHIL 17 (2), 21-26, 2021
22021
Inhibition of sensory neuron driven acute, inflammatory, and neuropathic pain using a humanised chemogenetic system
J Perez-Sanchez, SJ Middleton, LA Pattison, H Hilton, MA Awadelkareem, ...
bioRxiv, 2023.03. 21.533690, 2023
12023
Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons
J Scaber, I Thomas-Wright, AJ Clark, Y Xu, BF Vahsen, M Carcolé, ...
Stem Cell Reports, 2024
2024
Advances and challenges in modeling inherited peripheral neuropathies using iPSCs
J Van Lent, R Prior, G Pérez Siles, AN Cutrupi, ML Kennerson, ...
Experimental & Molecular Medicine, 1-17, 2024
2024
MYELINATED HUMAN SENSORY NEURONS PROVIDE A PLATFORM FOR THE REPRODUCIBLE SCREENING OF PERIPHERAL NERVE-REACTIVE AUTOANTIBODIES IN PATIENT SERA
J Fehmi, A Candalija, G Baskozos, A Clark, A Davies, S Rinaldi
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 27, S33-S34, 2022
2022
Myelinated, human stem cell-derived sensory neurons for screening for the presence of peripheral nerve-reactive autoantibodies in patient sera
A Davies, J Fehmi, A Candalija, A Clark, S Rinaldi
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 26 (3), 353-354, 2021
2021
Molecular and cellular correlates of human nerve regeneration: ADCYAP1/PACAP enhance nerve outgrowth (vol 143, pg 2009, 2020)
G Baskozos, O Sandy-Hindmarch, AJ Clark, K Windsor, P Karlsson, ...
BRAIN 144 (5), 2021
2021
Molecular and cellular correlates of human nerve regeneration: ADCYAP1 encoding PACAP enhances sensory neuron outgrowth
AB Schmid, G Baskozos, K Windsor, P Karlsson, O Sandy-Hindmarch, ...
bioRxiv, 686618, 2019
2019
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