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Lars Verschuren
Lars Verschuren
Scientist Systems Biology
在 tno.nl 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mouse models for atherosclerosis and pharmaceutical modifiers
S Zadelaar, R Kleemann, L Verschuren, J de Vries-Van der Weij, ...
Arteriosclerosis, thrombosis, and vascular biology 27 (8), 1706-1721, 2007
6972007
Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models
R Kleemann, L Verschuren, M Morrison, S Zadelaar, MJ van Erk, ...
Atherosclerosis 218 (1), 44-52, 2011
4582011
Fibrates down-regulate IL-1–stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB–C/EBP-β complex formation
R Kleemann, PP Gervois, L Verschuren, B Staels, HMG Princen, ...
Blood, The Journal of the American Society of Hematology 101 (2), 545-551, 2003
2872003
Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis
R Kleemann, L Verschuren, MJ Van Erk, Y Nikolsky, NHP Cnubben, ...
Genome biology 8, 1-16, 2007
2832007
Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro
R Kleemann, L Verschuren, BJ de Rooij, J Lindeman, MM de Maat, ...
Blood 103 (11), 4188-4194, 2004
2452004
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease
L Verschuren, T Kooistra, J Bernhagen, PJ Voshol, DM Ouwens, ...
Circulation research 105 (1), 99-107, 2009
1972009
Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance
R Kleemann, M van Erk, L Verschuren, AM van den Hoek, M Koek, ...
PloS one 5 (1), e8817, 2010
1822010
Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice
KA Grimaldi, B van Ommen, JM Ordovas, LD Parnell, JC Mathers, ...
Genes & nutrition 12, 1-12, 2017
1252017
Effect of low dose atorvastatin versus diet-induced cholesterol lowering on atherosclerotic lesion progression and inflammation in apolipoprotein E* 3–Leiden transgenic mice
L Verschuren, R Kleemann, EH Offerman, AJ Szalai, SJ Emeis, ...
Arteriosclerosis, thrombosis, and vascular biology 25 (1), 161-167, 2005
1182005
LXR agonist suppresses atherosclerotic lesion growth and promotes lesion regression in apoE* 3Leiden mice: time course and mechanismss⃞
L Verschuren, J de Vries-van der Weij, S Zadelaar, R Kleemann, ...
Journal of lipid research 50 (2), 301-311, 2009
1122009
Resolvin E1 attenuates atherosclerosis in absence of cholesterol-lowering effects and on top of atorvastatin
K Salic, MC Morrison, L Verschuren, PY Wielinga, L Wu, R Kleemann, ...
Atherosclerosis 250, 158-165, 2016
1072016
Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo
M Morrison, R van der Heijden, P Heeringa, E Kaijzel, L Verschuren, ...
Atherosclerosis 233 (1), 149-156, 2014
1072014
Butyrate restores HFD-induced adaptations in brain function and metabolism in mid-adult obese mice
IAC Arnoldussen, M Wiesmann, CE Pelgrim, EM Wielemaker, ...
International journal of obesity 41 (6), 935-944, 2017
942017
Transgenic flavonoid tomato intake reduces C-reactive protein in human C-reactive protein transgenic mice more than wild-type tomato
D Rein, E Schijlen, T Kooistra, K Herbers, L Verschuren, R Hall, ...
The Journal of nutrition 136 (9), 2331-2337, 2006
912006
Fenofibrate reduces atherogenesis in ApoE* 3Leiden mice: evidence for multiple antiatherogenic effects besides lowering plasma cholesterol
T Kooistra, L Verschuren, J de Vries-Van der Weij, W Koenig, K Toet, ...
Arteriosclerosis, thrombosis, and vascular biology 26 (10), 2322-2330, 2006
872006
A Dietary Mixture Containing Fish Oil, Resveratrol, Lycopene, Catechins, and Vitamins E and C Reduces Atherosclerosis in Transgenic Mice1–3
L Verschuren, PY Wielinga, W van Duyvenvoorde, S Tijani, K Toet, ...
The Journal of nutrition 141 (5), 863-869, 2011
662011
Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice
RAJ Zwamborn, RC Slieker, PCA Mulder, I Zoetemelk, L Verschuren, ...
Scientific reports 7 (1), 43261, 2017
602017
Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE∗ 3Leiden mice
MC Morrison, W Liang, P Mulder, L Verschuren, E Pieterman, K Toet, ...
Journal of hepatology 62 (5), 1180-1186, 2015
602015
Obeticholic acid modulates serum metabolites and gene signatures characteristic of human NASH and attenuates inflammation and fibrosis progression in Ldlr‐/‐. leiden mice
MC Morrison, L Verschuren, K Salic, J Verheij, A Menke, PY Wielinga, ...
Hepatology communications 2 (12), 1513-1532, 2018
592018
The BCR-ABL1 inhibitors imatinib and ponatinib decrease plasma cholesterol and atherosclerosis, and nilotinib and ponatinib activate coagulation in a translational mouse model
MG Pouwer, EJ Pieterman, L Verschuren, MPM Caspers, C Kluft, ...
Frontiers in cardiovascular medicine 5, 55, 2018
582018
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