| IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression A Sadik, LFS Patterson, S Öztürk, SR Mohapatra, V Panitz, PF Secker, ... Cell 182 (5), 1252-1270. e34, 2020 | 339 | 2020 |
| The therapeutic potential of targeting tryptophan catabolism in cancer CA Opitz, LF Somarribas Patterson, SR Mohapatra, DL Dewi, A Sadik, ... British journal of cancer 122 (1), 30-44, 2020 | 198 | 2020 |
| Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas K Aslan, V Turco, J Blobner, JK Sonner, AR Liuzzi, NG Núñez, D De Feo, ... Nature communications 11 (1), 931, 2020 | 136 | 2020 |
| The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner AM Heberle, PR Navas, M Langelaar-Makkinje, K Kasack, A Sadik, ... Life science alliance 2 (2), 2019 | 68 | 2019 |
| Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation T Kessler, F Sahm, A Sadik, D Stichel, A Hertenstein, G Reifenberger, ... Neuro-oncology 20 (3), 367-379, 2018 | 61 | 2018 |
| Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation I Adam, DL Dewi, J Mooiweer, A Sadik, SR Mohapatra, B Berdel, M Keil, ... Oncoimmunology 7 (12), e1486353, 2018 | 54 | 2018 |
| Hypoxia inducible factor 1α inhibits the expression of immunosuppressive tryptophan-2, 3-dioxygenase in glioblastoma SR Mohapatra, A Sadik, LO Tykocinski, J Dietze, G Poschet, I Heiland, ... Frontiers in Immunology 10, 2762, 2019 | 37 | 2019 |
| Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis S Nothdurft, C Thumser-Henner, F Breitenbücher, RA Okimoto, M Dorsch, ... Oncogenesis 9 (11), 102, 2020 | 33 | 2020 |
| Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma V Panitz, S Končarević, A Sadik, D Friedel, T Bausbacher, S Trump, ... Theranostics 11 (19), 9217, 2021 | 23 | 2021 |
| Methylome analyses of three glioblastoma cohorts reveal chemotherapy sensitivity markers within DDR genes T Kessler, A Berberich, A Sadik, F Sahm, T Gorlia, C Meisner, ... Cancer medicine 9 (22), 8373-8385, 2020 | 20 | 2020 |
| Hypoxia routes tryptophan homeostasis towards increased tryptamine production SR Mohapatra, A Sadik, S Sharma, G Poschet, HM Gegner, TV Lanz, ... Frontiers in immunology 12, 590532, 2021 | 13 | 2021 |
| Spatial probabilistic mapping of metabolite ensembles in mass spectrometry imaging D Abu Sammour, JL Cairns, T Boskamp, C Marsching, T Kessler, ... Nature communications 14 (1), 1823, 2023 | 11 | 2023 |
| ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition A Bakr, J Hey, G Sigismondo, CS Liu, A Sadik, A Goyal, A Cross, RL Iyer, ... Nucleic acids research 49 (20), 11666-11689, 2021 | 10 | 2021 |
| Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy C Kober, J Roewe, N Schmees, L Roese, U Roehn, B Bader, D Stoeckigt, ... Journal for Immunotherapy of Cancer 11 (11), 2023 | 4 | 2023 |
| KS01. 3. A Tumoral MHC class II expression in gliomas drives T cell exhaustion Y Chih, K Sahm, A Sadik, T Bunse, N Trautwein, S Pusch, S Stevanovic, ... Neuro-oncology 23 (Supplement_2), ii3-ii3, 2021 | 3 | 2021 |
| Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in Glioblastoma LC Foerster, O Kaya, V Wüst, M Bekavac, KC Ziegler, V Akcay, ... bioRxiv, 2023.09. 15.557713, 2023 | | 2023 |
| Interleukin-4-induced gene 1 (il4i1) and respective metabolites as biomarkers for cancer A Boehme, S Trump, LFS Patterson, A Sadik, CA Opitz US Patent App. 17/783,953, 2023 | | 2023 |
| The MTORC1-AHR pathway sustains translation and autophagy in tumours under tryptophan stress P Holfelder, L Hensen, MT Prentzell, PR Navas, M Solvay, A Sadik, ... bioRxiv, 2023.01. 16.523931, 2023 | | 2023 |
| Tryptophan stress activates EGFR-RAS-signaling to MTORC1 and p38/MAPK to sustain translation and AHR-dependent autophagy 2 P Pfänder, L Hensen, PR Navas, M Solvay, MT Prentzell, A Sadik, ... bioRxiv, 2023 | | 2023 |
| 165 PAHR: the pan-cancer AHR signature pipeline P Schulz-Knappe, C Opitz, S Trump, A Sadik Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
Christiane A. OpitzDivision Head "Metabolic Crosstalk in Cancer", German Cancer Research Center (DKFZ)在 dkfz.de 的电子邮件经过验证
