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Bob Chen
Bob Chen
Computational Scientist, Genentech
在 gene.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
4062020
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ...
Cell 184 (26), 6262-6280. e26, 2021
1752021
Succinate produced by intestinal microbes promotes specification of tuft cells to suppress ileal inflammation
A Banerjee, CA Herring, B Chen, H Kim, AJ Simmons, AN Southard-Smith, ...
Gastroenterology 159 (6), 2101-2115. e5, 2020
1612020
Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury
Z Ma, NK Lytle, B Chen, N Jyotsana, SW Novak, CJ Cho, L Caplan, ...
Gastroenterology 162 (2), 604-620. e20, 2022
592022
ATAC-Me captures prolonged DNA methylation of dynamic chromatin accessibility loci during cell fate transitions
KR Barnett, BE Decato, TJ Scott, TJ Hansen, B Chen, J Attalla, AD Smith, ...
Molecular cell 77 (6), 1350-1364. e6, 2020
592020
Quantitative assessment of cell population diversity in single-cell landscapes
Q Liu, CA Herring, Q Sheng, J Ping, AJ Simmons, B Chen, A Banerjee, ...
PLoS biology 16 (10), e2006687, 2018
422018
Single-cell computational strategies for lineage reconstruction in tissue systems
CA Herring, B Chen, ET McKinley, KS Lau
Cellular and molecular gastroenterology and hepatology 5 (4), 539-548, 2018
412018
Automated quality control and cell identification of droplet-based single-cell data using dropkick
CN Heiser, VM Wang, B Chen, JJ Hughey, KS Lau
Genome Research, gr. 271908.120, 2021
322021
Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment
PV Taufalele, W Wang, AJ Simmons, AN Southard-Smith, B Chen, ...
Acta biomaterialia 163, 365-377, 2023
282023
Dual indexed library design enables compatibility of in-Drop single-cell RNA-sequencing with exAMP chemistry sequencing platforms
AN Southard-Smith, AJ Simmons, B Chen, AL Jones, MA Ramirez Solano, ...
BMC genomics 21, 1-15, 2020
272020
Mining tasks and task characteristics from electronic health record audit logs with unsupervised machine learning
B Chen, W Alrifai, C Gao, B Jones, L Novak, N Lorenzi, D France, B Malin, ...
Journal of the American Medical Informatics Association 28 (6), 1168-1177, 2021
252021
Use of single-cell-omic technologies to study the gastrointestinal tract and diseases, from single cell identities to patient features
M Islam, B Chen, JM Spraggins, RT Kelly, KS Lau
Gastroenterology 159 (2), 453-466. e1, 2020
222020
Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors
CN Heiser, AJ Simmons, F Revetta, ET McKinley, MA Ramirez-Solano, ...
Cell 186 (25), 5620-5637. e16, 2023
132023
MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors
RE Brown, J Jacobse, SA Anant, KM Blunt, B Chen, PN Vega, CT Jones, ...
JCI Insight 7 (10), e153045, 2022
132022
Coregulator Sin3a promotes postnatal murine β-cell fitness by regulating genes in Ca2+ homeostasis, cell survival, vesicle biosynthesis, glucose metabolism, and stress response
X Yang, SM Graff, CN Heiser, KH Ho, B Chen, AJ Simmons, ...
Diabetes 69 (6), 1219-1231, 2020
132020
Deciphering the cancer microenvironment from bulk data with EcoTyper
A Rolong, B Chen, KS Lau
Cell 184 (21), 5306-5308, 2021
112021
Processing single-cell RNA-seq data for dimension reduction-based analyses using open-source tools
B Chen, MA Ramirez-Solano, CN Heiser, Q Liu, KS Lau
STAR protocols 2 (2), 100450, 2021
102021
pyNVR: investigating factors affecting feature selection from scRNA-seq data for lineage reconstruction
B Chen, CA Herring, KS Lau
Bioinformatics 35 (13), 2335-2337, 2019
102019
A contamination focused approach for optimizing the single-cell RNA-seq experiment
D Arceneaux, Z Chen, AJ Simmons, CN Heiser, AN Southard-Smith, ...
Iscience 26 (7), 2023
52023
Measuring collaboration through concurrent electronic health record usage: network analysis study
P Li, B Chen, E Rhodes, J Slagle, MW Alrifai, D France, Y Chen
JMIR medical informatics 9 (9), e28998, 2021
52021
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