| TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion O Khan, JR Giles, S McDonald, S Manne, SF Ngiow, KP Patel, MT Werner, ... Nature 571 (7764), 211-218, 2019 | 1292 | 2019 |
| Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells JA Fraietta, CL Nobles, MA Sammons, S Lundh, SA Carty, TJ Reich, ... Nature 558 (7709), 307-312, 2018 | 782 | 2018 |
| An NK-like CAR T cell transition in CAR T cell dysfunction CR Good, MA Aznar, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ... Cell 184 (25), 6081-6100. e26, 2021 | 258 | 2021 |
| p53 mediates target gene association with nuclear speckles for amplified RNA expression KA Alexander, A Coté, SC Nguyen, L Zhang, O Gholamalamdari, ... Molecular cell 81 (8), 1666-1681. e6, 2021 | 82 | 2021 |
| TRIM28 controls genomic imprinting through distinct mechanisms during and after early genome-wide reprogramming KA Alexander, X Wang, M Shibata, AG Clark, MJ García-García Cell reports 13 (6), 1194-1205, 2015 | 53 | 2015 |
| p63 establishes epithelial enhancers at critical craniofacial development genes E Lin-Shiao, Y Lan, J Welzenbach, KA Alexander, Z Zhang, M Knapp, ... Science advances 5 (5), eaaw0946, 2019 | 52 | 2019 |
| Reverse transcriptase inhibition disrupts repeat element life cycle in colorectal cancer M Rajurkar, AR Parikh, A Solovyov, E You, AS Kulkarni, C Chu, KH Xu, ... Cancer discovery 12 (6), 1462-1481, 2022 | 37 | 2022 |
| Integrated network analysis reveals distinct regulatory roles of transcription factors and microRNAs Y Guo, K Alexander, AG Clark, A Grimson, H Yu Rna 22 (11), 1663-1672, 2016 | 29 | 2016 |
| pre-mRNA spatial distributions suggest that splicing can occur post-transcriptionally A Coté, C Coté, S Bayatpour, HL Drexler, KA Alexander, F Chen, ... | 26* | 2020 |
| The transcriptional repressive activity of KRAB zinc finger proteins does not correlate with their ability to recruit TRIM28 KE Murphy, NA Shylo, KA Alexander, AJ Churchill, C Copperman, ... PLoS One 11 (9), e0163555, 2016 | 17 | 2016 |
| The role of BPIFA1 in upper airway microbial infections and correlated diseases YA Tsou, MC Tung, KA Alexander, WD Chang, MH Tsai, HL Chen, ... BioMed research international 2018 (1), 2021890, 2018 | 15 | 2018 |
| Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks AN Catizone, CR Good, KA Alexander, SL Berger, MA Sammons Cell Cycle 18 (8), 809-823, 2019 | 12 | 2019 |
| Post-transcriptional splicing can occur in a slow-moving zone around the gene A Coté, A O'Farrell, I Dardani, M Dunagin, C Coté, Y Wan, S Bayatpour, ... elife 12, RP91357, 2024 | 10 | 2024 |
| Car-t cell therapies with enhanced efficacy SL Berger, KA Alexander, SM McDonald US Patent App. 17/441,576, 2023 | 9 | 2023 |
| Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer KA Alexander, R Yu, N Skuli, NJ Coffey, S Nguyen, C Faunce, H Huang, ... bioRxiv, 2023 | 8 | 2023 |
| TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells SM Collins, KA Alexander, S Lundh, AJ Dimitri, Z Zhang, CR Good, ... Science Advances 9 (29), eadh2605, 2023 | 7 | 2023 |
| CTCF/cohesin organize the ground state of chromatin-nuclear speckle association R Yu, S Roseman, AP Siegenfeld, SC Nguyen, EF Joyce, BB Liau, ... bioRxiv, 2023.07. 22.550178, 2023 | 5 | 2023 |
| Imprinted gene expression at the Dlk1-Dio3 cluster is controlled by both maternal and paternal IG-DMRs in a tissue-specific fashion KA Alexander, MJ García-García bioRxiv, 536102, 2019 | 3 | 2019 |
| Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment CR Good, S Kuramitsu, P Samareh, G Donahue, K Ishiyama, Y Ma, ... Cancer Research 81 (13_Supplement), 60-60, 2021 | 1 | 2021 |
| Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease EC Walker, S Javati, EM Todd, JP Matlam, X Lin, M Bryant, E Krone, ... Nature Immunology, 1-12, 2024 | | 2024 |
Shelley L BergerProfessor of Cell and Developmental Biology, University of Pennsylvania在 upenn.edu 的电子邮件经过验证
