Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration Z Melamed, J López-Erauskin, MW Baughn, O Zhang, K Drenner, Y Sun, ... Nature neuroscience 22 (2), 180-190, 2019 | 409 | 2019 |
Cytoplasmic TDP-43 de-mixing independent of stress granules drives inhibition of nuclear import, loss of nuclear TDP-43, and cell death F Gasset-Rosa, S Lu, H Yu, C Chen, Z Melamed, L Guo, J Shorter, ... Neuron 102 (2), 339-357. e7, 2019 | 374 | 2019 |
Alternative splicing regulates biogenesis of miRNAs located across exon-intron junctions Z Melamed, A Levy, R Ashwal-Fluss, G Lev-Maor, K Mekahel, N Atias, ... Molecular cell 50 (6), 869-881, 2013 | 111 | 2013 |
DNA methylation directs microRNA biogenesis in mammalian cells O Glaich, S Parikh, RE Bell, K Mekahel, M Donyo, Y Leader, R Shayevitch, ... Nature communications 10 (1), 5657, 2019 | 109 | 2019 |
Interactions of melanoma cells with distal keratinocytes trigger metastasis via notch signaling inhibition of MITF T Golan, AR Messer, A Amitai-Lange, Z Melamed, R Ohana, RE Bell, ... Molecular cell 59 (4), 664-676, 2015 | 100 | 2015 |
Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies MW Baughn, Z Melamed, J López-Erauskin, MS Beccari, K Ling, A Zuberi, ... Science 379 (6637), 1140-1149, 2023 | 55 | 2023 |
Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype F Theunissen, RS Anderton, FL Mastaglia, LL Flynn, SJ Winter, I James, ... Frontiers in Aging Neuroscience 13, 658226, 2021 | 45 | 2021 |
TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia H Sidibé, Y Khalfallah, S Xiao, NB Gómez, H Fakim, EMH Tank, ... Brain 144 (11), 3461-3476, 2021 | 27 | 2021 |
Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene M Amit, N Sela, H Keren, Z Melamed, I Muler, N Shomron, S Izraeli, G Ast BMC molecular biology 8, 1-15, 2007 | 23 | 2007 |
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation J Lopez-Erauskin, M Bravo-Hernandez, M Presa, MW Baughn, ... Nature neuroscience 27 (1), 34-47, 2024 | 13 | 2024 |
Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease AR Agra Almeida Quadros, Z Li, X Wang, IS Ndayambaje, S Aryal, ... Acta Neuropathologica 147 (1), 9, 2024 | 7 | 2024 |
TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD H Sidibé, Y Khalfallah, S Xiao, NB Gómez, EMH Tank, G Di Tomasso, ... bioRxiv, 2020.09. 15.298455, 2020 | 4 | 2020 |
Compounds and methods for increasing stmn2 expression HH Bui, DW Cleveland, Z Melamed US Patent 11,833,168, 2023 | | 2023 |