Natural history of β-cell adaptation and failure in type 2 diabetes EU Alejandro, B Gregg, M Blandino-Rosano, C Cras-Méneur, ... Molecular aspects of medicine 42, 19-41, 2015 | 266 | 2015 |
Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing M Blandino-Rosano, R Barbaresso, M Jimenez-Palomares, N Bozadjieva, ... Nature communications 8 (1), 16014, 2017 | 143 | 2017 |
mTORC1 signaling and regulation of pancreatic β-cell mass M Blandino-Rosano, AY Chen, JO Scheys, EU Alejandro, AP Gould, ... Cell Cycle 11 (10), 1892-1902, 2012 | 99 | 2012 |
Anti-proliferative effect of pro-inflammatory cytokines in cultured β cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of … M Blandino-Rosano, G Perez-Arana, JM Mellado-Gil, C Segundo, ... Journal of molecular endocrinology 41 (1), 35-44, 2008 | 93 | 2008 |
Decreased IRS signaling impairs β-cell cycle progression and survival in transgenic mice overexpressing S6K in β-cells L Elghazi, N Balcazar, M Blandino-Rosano, C Cras-Méneur, S Fatrai, ... Diabetes 59 (10), 2390-2399, 2010 | 74 | 2010 |
Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes G Navarro, C Allard, JJ Morford, W Xu, S Liu, AJR Molinas, SM Butcher, ... JCI insight 3 (12), 2018 | 64 | 2018 |
Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion N Bozadjieva, M Blandino-Rosano, J Chase, XQ Dai, K Cummings, ... The Journal of clinical investigation 127 (12), 4379-4393, 2017 | 54 | 2017 |
Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development L Elghazi, M Blandino-Rosano, E Alejandro, C Cras-Méneur, ... Molecular metabolism 6 (6), 560-573, 2017 | 52 | 2017 |
Overexpression of kinase-dead mTOR impairs glucose homeostasis by regulating insulin secretion and not β-cell mass EU Alejandro, N Bozadjieva, M Blandino-Rosano, MA Wasan, L Elghazi, ... Diabetes 66 (8), 2150-2162, 2017 | 47 | 2017 |
Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis M Sadagurski, T Landeryou, M Blandino-Rosano, G Cady, L Elghazi, ... American Journal of Physiology-Endocrinology and Metabolism 306 (11), E1305 …, 2014 | 38 | 2014 |
Exposure of mouse embryonic pancreas to metformin enhances the number of pancreatic progenitors B Gregg, L Elghazi, EU Alejandro, MR Smith, M Blandino-Rosano, ... Diabetologia 57, 2566-2575, 2014 | 31 | 2014 |
Nitric oxide is a mediator of antiproliferative effects induced by proinflammatory cytokines on pancreatic beta cells L Quintana-Lopez, M Blandino-Rosano, G Perez-Arana, A Cebada-Aleu, ... Mediators of inflammation 2013 (1), 905175, 2013 | 28 | 2013 |
Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21 Cip M Blandino-Rosano, EU Alejandro, A Sathyamurthy, JO Scheys, B Gregg, ... Diabetologia 55, 1380-1389, 2012 | 28 | 2012 |
Decrease in β-cell proliferation precedes apoptosis during diabetes development in bio-breeding/worcester rat: beneficial role of exendin-4 G Perez-Arana, M Blandino-Rosano, A Prada-Oliveira, ... Endocrinology 151 (6), 2538-2546, 2010 | 28 | 2010 |
Glucagon resistance and decreased susceptibility to diabetes in a model of chronic hyperglucagonemia N Bozadjieva Kramer, C Lubaczeuski, M Blandino-Rosano, G Barker, ... Diabetes 70 (2), 477-491, 2021 | 23 | 2021 |
4E-BP2/SH2B1/IRS2 are part of a novel feedback loop that controls β-cell mass M Blandino-Rosano, JO Scheys, M Jimenez-Palomares, R Barbaresso, ... Diabetes 65 (8), 2235-2248, 2016 | 18 | 2016 |
Glucose stimulates microRNA-199 expression in murine pancreatic β-cells JP Werneck-de-Castro, M Blandino-Rosano, D Hilfiker-Kleiner, ... Journal of Biological Chemistry 295 (5), 1261-1270, 2020 | 15 | 2020 |
GLP-1 mediated improvement of the glucose tolerance in the T2DM GK rat model after massive jejunal resection JA Prada-Oliveira, A Camacho-Ramirez, J Salas-Alvarez, ... Annals of Anatomy-Anatomischer Anzeiger 223, 1-7, 2019 | 15 | 2019 |
Bariatric surgery influences β-cell turnover in non obese rats A Camacho Ramírez, M Blandino Rosano, MC Segundo Iglesias, ... Universidad de Murcia. Departamento de Biología Celular e Histología, 2017 | 14 | 2017 |
Nutrient sensor mTORC1 regulates insulin secretion by modulating β-cell autophagy T Israeli, Y Riahi, P Garzon, RA Louzada, JP Werneck-de-Castro, ... Diabetes 71 (3), 453-469, 2022 | 11 | 2022 |