Defining the role of common variation in the genomic and biological architecture of adult human height AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ... Nature genetics 46 (11), 1173-1186, 2014 | 2089 | 2014 |
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation International HIV Controllers Study Science 330 (6010), 1551-1557, 2010 | 1121 | 2010 |
Exome sequencing and the genetic basis of complex traits A Kiezun, K Garimella, R Do, NO Stitziel, BM Neale, PJ McLaren, N Gupta, ... Nature genetics 44 (6), 623-630, 2012 | 506 | 2012 |
Influence of HLA-C expression level on HIV control R Apps, Y Qi, JM Carlson, H Chen, X Gao, R Thomas, Y Yuki, ... Science 340 (6128), 87-91, 2013 | 402 | 2013 |
Extremely low-coverage sequencing and imputation increases power for genome-wide association studies B Pasaniuc, N Rohland, PJ McLaren, K Garimella, N Zaitlen, H Li, ... Nature genetics 44 (6), 631-635, 2012 | 291 | 2012 |
Guanylate binding protein (GBP) 5 is an interferon-inducible inhibitor of HIV-1 infectivity C Krapp, D Hotter, A Gawanbacht, PJ McLaren, SF Kluge, CM Stürzel, ... Cell host & microbe 19 (4), 504-514, 2016 | 235 | 2016 |
Decreased Immune Activation in Resistance to HIV-1 Infection Is Associated with an Elevated Frequency of CD4+CD25+FOXP3+ Regulatory T Cells CM Card, PJ McLaren, C Wachihi, J Kimani, FA Plummer, KR Fowke The Journal of infectious diseases 199 (9), 1318-1322, 2009 | 224 | 2009 |
Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque M Rotger, J Dalmau, A Rauch, P McLaren, SE Bosinger, R Martinez, ... The Journal of clinical investigation 121 (6), 2391-2400, 2011 | 221 | 2011 |
GWAS identifies novel susceptibility loci on 6p21. 32 and 21q21. 3 for hepatocellular carcinoma in chronic hepatitis B virus carriers S Li, J Qian, Y Yang, W Zhao, J Dai, JX Bei, JN Foo, PJ McLaren, Z Li, ... PLoS genetics 8 (7), e1002791, 2012 | 213 | 2012 |
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load PJ McLaren, C Coulonges, I Bartha, TL Lenz, AJ Deutsch, A Bashirova, ... Proceedings of the National Academy of Sciences 112 (47), 14658-14663, 2015 | 180 | 2015 |
The impact of host genetic variation on infection with HIV-1 PJ McLaren, M Carrington Nature immunology 16 (6), 577-583, 2015 | 175 | 2015 |
Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants ER Holzinger, B Grady, MD Ritchie, HJ Ribaudo, EP Acosta, GD Morse, ... Pharmacogenetics and genomics 22 (12), 858-867, 2012 | 162 | 2012 |
HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1 N Izquierdo-Useros, M Lorizate, PJ McLaren, A Telenti, HG Kräusslich, ... PLoS pathogens 10 (7), e1004146, 2014 | 152 | 2014 |
HIV-Exposed Seronegative Commercial Sex Workers Show a Quiescent Phenotype in the CD4+ T Cell Compartment and Reduced Expression of HIV-Dependent … PJ McLaren, T Blake Ball, C Wachihi, W Jaoko, DJ Kelvin, A Danesh, ... The Journal of infectious diseases 202 (Supplement_3), S339-S344, 2010 | 149 | 2010 |
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control I Bartha, JM Carlson, CJ Brumme, PJ McLaren, ZL Brumme, M John, ... elife 2, e01123, 2013 | 142 | 2013 |
Severe viral respiratory infections in children with IFIH1 loss-of-function mutations S Asgari, LJ Schlapbach, S Anchisi, C Hammer, I Bartha, T Junier, ... Proceedings of the National Academy of Sciences 114 (31), 8342-8347, 2017 | 138 | 2017 |
Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls PJ McLaren, C Coulonges, S Ripke, L Van Den Berg, S Buchbinder, ... PLoS pathogens 9 (7), e1003515, 2013 | 137 | 2013 |
The role of regulatory T cells in chronic and acute viral infections Y Keynan, CM Card, PJ McLaren, MR Dawood, K Kasper, KR Fowke Clinical infectious diseases 46 (7), 1046-1052, 2008 | 123 | 2008 |
Cohorts for the study of hiv-1—exposed but uninfected individuals: Benefits and limitations RE Horton, PJ McLaren, K Fowke, J Kimani, TB Ball The Journal of infectious diseases 202 (Supplement_3), S377-S381, 2010 | 121 | 2010 |
Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers TB Ball, H Ji, J Kimani, P McLaren, C Marlin, AVS Hill, FA Plummer Aids 21 (9), 1091-1101, 2007 | 119 | 2007 |