Coarse-grained molecular simulation of diffusion and reaction kinetics in a crowded virtual cytoplasm D Ridgway, G Broderick, A Lopez-Campistrous, M Ru’aini, P Winter, ... Biophysical journal 94 (10), 3748-3759, 2008 | 219 | 2008 |
Comparison of SDS‐ and methanol‐assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2‐D LC‐MS/MS N Zhang, R Chen, N Young, D Wishart, P Winter, JH Weiner, L Li Proteomics 7 (4), 484-493, 2007 | 151 | 2007 |
Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives CY Tseng, JY Mane, P Winter, L Johnson, T Huzil, E Izbicka, RF Luduena, ... Molecular Cancer 9, 1-19, 2010 | 47 | 2010 |
Novel colchicine derivatives and their anti-cancer activity L Johnson, I Swie Goping, A Rieger, J Y Mane, T Huzil, A Banerjee, ... Current topics in medicinal chemistry 17 (22), 2538-2558, 2017 | 36 | 2017 |
Modeling the Colchicum autumnale Tubulin and a Comparison of Its Interaction with Colchicine to Human Tubulin I Spasevska, AT Ayoub, P Winter, J Preto, GKS Wong, C Dumontet, ... International journal of molecular sciences 18 (8), 1676, 2017 | 30 | 2017 |
Modeling the yew tree tubulin and a comparison of its interaction with paclitaxel to human tubulin JA Tuszynski, TJA Craddock, JY Mane, K Barakat, CY Tseng, M Gajewski, ... Pharmaceutical research 29, 3007-3021, 2012 | 30 | 2012 |
Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer W Wang, H Zhang, X Wang, J Patterson, P Winter, K Graham, S Ghosh, ... Protoplasma 254, 1163-1173, 2017 | 26 | 2017 |
EDEn–electroceutical design environment: ion channel tissue expression database with small molecule modulators CDM Churchill, P Winter, JA Tuszynski, M Levin Iscience 11, 42-56, 2019 | 20 | 2019 |
Designing and testing of novel taxanes to probe the highly complex mechanisms by which taxanes bind to microtubules and cause cytotoxicity to cancer cells M St. George, AT Ayoub, A Banerjee, CDM Churchill, P Winter, ... PLoS One 10 (6), e0129168, 2015 | 20 | 2015 |
Computational design and biological testing of highly cytotoxic colchicine ring A modifications J Torin Huzil, P Winter, L Johnson, AL Weis, T Bakos, A Banerjee, ... Chemical biology & drug design 75 (6), 541-550, 2010 | 19 | 2010 |
The development of a targeted and more potent, anti-Inflammatory derivative of colchicine: Implications for gout G Paré, J Vitry, F Marceau, M Vaillancourt, P Winter, H Bachelard, ... Biochemical Pharmacology 180, 114125, 2020 | 18 | 2020 |
Mathematical and computational modeling in biology at multiple scales JA Tuszynski, P Winter, D White, CY Tseng, KK Sahu, F Gentile, ... Theoretical Biology and Medical Modelling 11, 1-42, 2014 | 18 | 2014 |
Inactivation of protein tyrosine phosphatases by peracids correlates with the hydrocarbon chain length A Kuban-Jankowska, M Gorska, JA Tuszynski, CDM Churchill, P Winter, ... Cellular Physiology and Biochemistry 36 (3), 1069-1083, 2015 | 14 | 2015 |
Experimental and Computational Study of the Interaction of Novel Colchicinoids with a Recombinant Human α I/β I‐Tubulin Heterodimer JY Mane, V Semenchenko, R Perez‐Pineiro, P Winter, D Wishart, ... Chemical biology & drug design 82 (1), 60-70, 2013 | 14 | 2013 |
Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45 A Kuban-Jankowska, JA Tuszynski, P Winter, M Gorska, N Knap, ... PloS one 7 (12), e52495, 2012 | 13 | 2012 |
A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase H Freedman, P Winter, J Tuszynski, DL Tyrrell, M Houghton Journal of Biological Chemistry 293 (25), 9696-9705, 2018 | 12 | 2018 |
Chemical synthesis, pharmacological evaluation and in silico analysis of new 2, 3, 3a, 4, 5, 6-hexahydrocyclopenta [c] pyrazole derivatives as potential anti-mitotic agents M Minu, D Singh, T Mahaddalkar, M Lopus, P Winter, AT Ayoub, ... Bioorganic & Medicinal Chemistry Letters 26 (16), 3855-3861, 2016 | 12 | 2016 |
A nanometric probe of the local proton concentration in microtubule-based biophysical systems AP Kalra, BB Eakins, SI Vagin, H Wang, SD Patel, P Winter, M Aminpour, ... Nano letters 22 (1), 517-523, 2021 | 7 | 2021 |
Revealing and attenuating the electrostatic properties of tubulin and its polymers AP Kalra, SD Patel, BB Eakins, S Riddell, P Kumar, P Winter, J Preto, ... Small 17 (1), 2003560, 2021 | 7 | 2021 |
Molecular dynamics and related computational methods with applications to drug discovery J Preto, F Gentile, P Winter, C Churchill, SI Omar, JA Tuszynski Coupled Mathematical Models for Physical and Biological Nanoscale Systems …, 2018 | 7 | 2018 |