SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species M Moustaqil, E Ollivier, HP Chiu, S Van Tol, P Rudolffi-Soto, C Stevens, ... Emerging microbes & infections 10 (1), 178-195, 2021 | 208 | 2021 |
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice J Overman, F Fontaine, M Moustaqil, D Mittal, E Sierecki, N Sacilotto, ... Elife 6, e21221, 2017 | 53 | 2017 |
A cell-free approach to accelerate the study of protein–protein interactions in vitro E Sierecki, N Giles, M Polinkovsky, M Moustaqil, K Alexandrov, Y Gambin Interface focus 3 (5), 20130018, 2013 | 48 | 2013 |
R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma J Overman, F Fontaine, J Wylie-Sears, M Moustaqil, L Huang, M Meurer, ... Elife 8, e43026, 2019 | 47 | 2019 |
Rapid mapping of interactions between human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy E Sierecki, LM Stevers, N Giles, ME Polinkovsky, M Moustaqil, S Mureev, ... Molecular & Cellular Proteomics 13 (9), 2233-2245, 2014 | 46 | 2014 |
Small-molecule inhibitors of the SOX18 transcription factor F Fontaine, J Overman, M Moustaqil, S Mamidyala, A Salim, ... Cell chemical biology 24 (3), 346-359, 2017 | 45 | 2017 |
Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor M Moustaqil, F Fontaine, J Overman, A McCann, TL Bailey, ... Nucleic acids research 46 (21), 11381-11395, 2018 | 24 | 2018 |
SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for … M Moustaqil, E Ollivier, HP Chiu, S Van Tol, P Rudolffi-Soto, C Stevens, ... Biorxiv, 2020.06. 05.135699, 2020 | 16 | 2020 |
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species … M Moustaqil, E Ollivier, HP Chiu, S Van Tol, P Rudolffi-Soto, C Stevens, ... | 14 | 2021 |
Biophysical techniques for target validation and drug discovery in transcription-targeted therapy M Moustaqil, Y Gambin, E Sierecki International Journal of Molecular Sciences 21 (7), 2301, 2020 | 14 | 2020 |
A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity AJ McCann, J Lou, M Moustaqil, MS Graus, A Blum, F Fontaine, H Liu, ... Nucleic Acids Research 49 (19), 10931-10955, 2021 | 8 | 2021 |
A split-luciferase reporter recognizing GFP and mCherry tags to facilitate studies of protein–protein interactions M Moustaqil, A Bhumkar, L Gonzalez, L Raoul, DJB Hunter, P Carrive, ... International Journal of Molecular Sciences 18 (12), 2681, 2017 | 8 | 2017 |
The blood vasculature instructs lymphatic patterning in a SOX7‐dependent manner IKN Chiang, MS Graus, N Kirschnick, T Davidson, W Luu, R Harwood, ... The EMBO journal 42 (5), e109032, 2023 | 6 | 2023 |
Evolutionary Landscape of SOX Genes to Inform Genotype-to-Phenotype Relationships A Underwood, DT Rasicci, D Hinds, JT Mitchell, JK Zieba, J Mills, ... Genes 14 (1), 222, 2023 | 6 | 2023 |
Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach FR Fontaine, S Goodall, JW Prokop, CB Howard, M Moustaqil, S Kumble, ... Mabs 10 (4), 596-606, 2018 | 6 | 2018 |
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species … M Moustaqil, E Ollivier, HP Chiu, S Van Tol, P Rudolffi-Soto, C Stevens, ... DOI: https://doi. org/10.1080/22221751.2020 1870414, 178-195, 0 | 5 | |
Prion‐like protein polymerisation underlies signal transduction in innate immunity: The emergence of a universal mechanism? A O'Carroll, T Ve, M Moustaqil, N Giles, A Bhumkar, D Hunter, B Kobe, ... The FASEB Journal 31, 937.1-937.1, 2017 | 1 | 2017 |
Probing the architecture of the Mediator complex (939.3) E Sierecki, M Polinkovsky, N Giles, M Moustaqil, K Alexandrov, Y Gambin The FASEB Journal 28, 939.3, 2014 | 1 | 2014 |
Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice J Overman, F Fontaine, M Moustaqil, D Mittal, E Sierecki, N Sacilotto, ... Elife 12, e90408, 2023 | | 2023 |
SOX18 mutations associated with human HLTRS syndrome reveal modification of protein‐protein interactions MD Moustaqil The FASEB Journal 33 (S1), 458.15-458.15, 2019 | | 2019 |