| Establishment of patient-derived organoids and drug screening for biliary tract carcinoma Y Saito, T Muramatsu, Y Kanai, H Ojima, A Sukeda, N Hiraoka, E Arai, ... Cell reports 27 (4), 1265-1276. e4, 2019 | 188 | 2019 |
| Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy T Yanagita, Y Murata, D Tanaka, S Motegi, E Arai, EW Daniwijaya, ... JCI insight 2 (1), 2017 | 171 | 2017 |
| Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas E Arai, S Chiku, T Mori, M Gotoh, T Nakagawa, H Fujimoto, Y Kanai Carcinogenesis 33 (8), 1487-1493, 2012 | 154 | 2012 |
| Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues E Arai, Y Kanai, S Ushijima, H Fujimoto, K Mukai, S Hirohashi International journal of cancer 119 (2), 288-296, 2006 | 137 | 2006 |
| Lipidomic signatures and associated transcriptomic profiles of clear cell renal cell carcinoma K Saito, E Arai, K Maekawa, M Ishikawa, H Fujimoto, R Taguchi, ... Scientific reports 6 (1), 1-12, 2016 | 131 | 2016 |
| An integrated prognostic classifier for stage I lung adenocarcinoma based on mRNA, microRNA, and DNA methylation biomarkers AI Robles, E Arai, EA Mathé, H Okayama, AJ Schetter, D Brown, ... Journal of Thoracic Oncology 10 (7), 1037-1048, 2015 | 112 | 2015 |
| Genetic and epigenetic alterations during renal carcinogenesis E Arai, Y Kanai International journal of clinical and experimental pathology 4 (1), 58, 2011 | 107 | 2011 |
| DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma T Sato, E Arai, T Kohno, K Tsuta, S Watanabe, K Soejima, T Betsuyaku, ... PloS one 8 (3), e59444, 2013 | 106 | 2013 |
| Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer S Akatsuka, Y Yamashita, H Ohara, YT Liu, M Izumiya, K Abe, M Ochiai, ... PloS one 7 (8), e43403, 2012 | 106 | 2012 |
| Multilayer‐omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome E Arai, H Sakamoto, H Ichikawa, H Totsuka, S Chiku, M Gotoh, T Mori, ... International journal of cancer 135 (6), 1330-1342, 2014 | 99 | 2014 |
| Silencing of microRNA‐122 is an early event during hepatocarcinogenesis from non‐alcoholic steatohepatitis Y Takaki, Y Saito, A Takasugi, K Toshimitsu, S Yamada, T Muramatsu, ... Cancer science 105 (10), 1254-1260, 2014 | 90 | 2014 |
| Bile acids increase levels of microRNAs 221 and 222, leading to degradation of CDX2 during esophageal carcinogenesis J Matsuzaki, H Suzuki, H Tsugawa, M Watanabe, S Hossain, E Arai, ... Gastroenterology 145 (6), 1300-1311, 2013 | 89 | 2013 |
| Increased expression of DNA methyltransferase 1 (DNMT1) protein in uterine cervix squamous cell carcinoma and its precursor lesion M Sawada, Y Kanai, E Arai, S Ushijima, H Ojima, S Hirohashi Cancer letters 251 (2), 211-219, 2007 | 79 | 2007 |
| Epigenetic clustering of lung adenocarcinomas based on DNA methylation profiles in adjacent lung tissue: Its correlation with smoking history and chronic obstructive pulmonary … T Sato, E Arai, T Kohno, Y Takahashi, S Miyata, K Tsuta, S Watanabe, ... International journal of cancer 135 (2), 319-334, 2014 | 69 | 2014 |
| Genetic clustering of clear cell renal cell carcinoma based on array-comparative genomic hybridization: its association with DNA methylation alteration and patient outcome E Arai, S Ushijima, H Tsuda, H Fujimoto, F Hosoda, T Shibata, T Kondo, ... Clinical Cancer Research 14 (17), 5531-5539, 2008 | 68 | 2008 |
| Alterations of the spindle checkpoint pathway in clinicopathologically aggressive C p G island methylator phenotype clear cell renal cell carcinomas E Arai, M Gotoh, Y Tian, H Sakamoto, M Ono, A Matsuda, Y Takahashi, ... International journal of cancer 137 (11), 2589-2606, 2015 | 67 | 2015 |
| Genome‐wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma E Arai, S Ushijima, M Gotoh, H Ojima, T Kosuge, F Hosoda, T Shibata, ... International Journal of Cancer 125 (12), 2854-2862, 2009 | 65 | 2009 |
| Prognostic risk stratification of patients with urothelial carcinoma of the bladder with recurrence after radical cystectomy T Nakagawa, T Hara, T Kawahara, Y Ogata, H Nakanishi, M Komiyama, ... The Journal of urology 189 (4), 1275-1281, 2013 | 64 | 2013 |
| Genome-wide DNA methylation profiles in both precancerous conditions and clear cell renal cell carcinomas are correlated with malignant potential and patient outcome E Arai, S Ushijima, H Fujimoto, F Hosoda, T Shibata, T Kondo, S Yokoi, ... Carcinogenesis 30 (2), 214-221, 2009 | 62 | 2009 |
| Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: comparison with hepatitis virus-related carcinogenesis J Kuramoto, E Arai, Y Tian, N Funahashi, M Hiramoto, T Nammo, ... Carcinogenesis 38 (3), 261-270, 2017 | 61 | 2017 |
