Confinement of therapeutic enzymes in selectively permeable polymer vesicles by polymerization-induced self-assembly (PISA) reduces antibody binding and proteolytic susceptibility LD Blackman, S Varlas, MC Arno, ZH Houston, NL Fletcher, KJ Thurecht, ... ACS central science 4 (6), 718-723, 2018 | 193 | 2018 |
A pH-responsive coiled-coil peptide hydrogel NL Fletcher, CV Lockett, AF Dexter Soft Matter 7 (21), 10210-10218, 2011 | 94 | 2011 |
Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic AK Pearce, JD Simpson, NL Fletcher, ZH Houston, AV Fuchs, PJ Russell, ... Biomaterials 141, 330-339, 2017 | 78 | 2017 |
Overcoming Instability of Antibody‐Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies CB Howard, N Fletcher, ZH Houston, AV Fuchs, NRB Boase, JD Simpson, ... Advanced healthcare materials 5 (16), 2055-2068, 2016 | 63 | 2016 |
Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranostics Y Zhao, ZH Houston, JD Simpson, L Chen, NL Fletcher, AV Fuchs, ... Molecular pharmaceutics 14 (10), 3539-3549, 2017 | 51 | 2017 |
Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency AV Fuchs, BWC Tse, AK Pearce, MC Yeh, NL Fletcher, SS Huang, ... Biomacromolecules 16 (10), 3235-3247, 2015 | 48 | 2015 |
Poly (2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures D Pizzi, J Humphries, JP Morrow, NL Fletcher, CA Bell, KJ Thurecht, ... European Polymer Journal 121, 109258, 2019 | 44 | 2019 |
Modulating Targeting of Poly (ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies J Cui, Y Ju, ZH Houston, JJ Glass, NL Fletcher, S Alcantara, Q Dai, ... Advanced healthcare materials 8 (9), 1801607, 2019 | 44 | 2019 |
Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies ZH Houston, J Bunt, KS Chen, S Puttick, CB Howard, NL Fletcher, ... ACS Central Science 6 (5), 727-738, 2020 | 43 | 2020 |
Engineering fluorescent gold nanoclusters using xanthate-functionalized hydrophilic polymers: Toward enhanced monodispersity and stability VG Deepagan, MN Leiske, NL Fletcher, D Rudd, T Tieu, N Kirkwood, ... Nano Letters 21 (1), 476-484, 2020 | 41 | 2020 |
Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation SS Thakur, YS Chen, ZH Houston, N Fletcher, NL Barnett, KJ Thurecht, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 102-107, 2019 | 41 | 2019 |
Synthesis, characterization and biological activities of semicarbazones and their copper complexes TK Venkatachalam, PV Bernhardt, CJ Noble, N Fletcher, GK Pierens, ... Journal of inorganic biochemistry 162, 295-308, 2016 | 39 | 2016 |
Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials NL Fletcher, ZH Houston, JD Simpson, RN Veedu, KJ Thurecht Chemical Communications 54 (82), 11538-11541, 2018 | 38 | 2018 |
Gold nanocluster-mediated cellular death under electromagnetic radiation A Cifuentes-Rius, A Ivask, S Das, N Penya-Auladell, L Fabregas, ... ACS applied materials & interfaces 9 (47), 41159-41167, 2017 | 38 | 2017 |
Controlling the Biological Fate of Micellar Nanoparticles: Balancing Stealth and Targeting AJ Sivaram, A Wardiana, S Alcantara, SE Sonderegger, NL Fletcher, ... ACS nano 14 (10), 13739-13753, 2020 | 37 | 2020 |
Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation JA Mills, F Liu, TR Jarrett, NL Fletcher, KJ Thurecht Biomaterials Science 10 (12), 3029-3053, 2022 | 32 | 2022 |
Polynitroxide copolymers to reduce biofilm fouling on surfaces NRB Boase, MDT Torres, NL Fletcher, C de la Fuente-Nunez, ... Polymer Chemistry 9 (43), 5308-5318, 2018 | 32 | 2018 |
Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract AM Dos Santos, AB Meneguin, DT Akhter, N Fletcher, ZH Houston, C Bell, ... European Journal of Pharmaceutics and Biopharmaceutics 158, 371-378, 2021 | 31 | 2021 |
Fabrication and characterization of hydrogels formed from designer coiled-coil fibril-forming peptides AF Dexter, NL Fletcher, RG Creasey, F Filardo, MW Boehm, KS Jack RSC Advances 7 (44), 27260-27271, 2017 | 30 | 2017 |
Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo AK Pearce, AV Fuchs, NL Fletcher, KJ Thurecht Pharmaceutical research 33 (10), 2388-2399, 2016 | 29 | 2016 |