Deletion of tumor necrosis factor death receptor inhibits amyloid β generation and prevents learning and memory deficits in Alzheimer's mice P He, Z Zhong, K Lindholm, L Berning, W Lee, C Lemere, M Staufenbiel, ... The Journal of cell biology 178 (5), 829-841, 2007 | 472 | 2007 |
BACE1 regulates voltage-gated sodium channels and neuronal activity DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ... Nature cell biology 9 (7), 755-764, 2007 | 387 | 2007 |
MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein HJ Cho, G Liu, SM Jin, L Parisiadou, C Xie, J Yu, L Sun, B Ma, J Ding, ... Human molecular genetics 22 (3), 608-620, 2013 | 304 | 2013 |
Levels of β-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment Z Zhong, M Ewers, S Teipel, K Bürger, A Wallin, K Blennow, P He, ... Archives of general psychiatry 64 (6), 718-726, 2007 | 281 | 2007 |
Interruption of β-catenin signaling reduces neurogenesis in Alzheimer's disease P He, Y Shen Journal of Neuroscience 29 (20), 6545-6557, 2009 | 163 | 2009 |
New evidence of mitochondria dysfunction in the female Alzheimer's disease brain: deficiency of estrogen receptor-β J Long, P He, Y Shen, R Li Journal of Alzheimer's disease 30 (3), 545-558, 2012 | 114 | 2012 |
Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients X Cheng, L Yang, P He, R Li, Y Shen Journal of Alzheimer's Disease 19 (2), 621-630, 2010 | 108 | 2010 |
Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons P He, Q Liu, J Wu, Y Shen The FASEB Journal 26 (1), 334, 2012 | 105 | 2012 |
Interleukin-17 inhibits adult hippocampal neurogenesis Q Liu, W Xin, P He, D Turner, J Yin, Y Gan, FD Shi, J Wu Scientific reports 4 (1), 7554, 2014 | 100 | 2014 |
Brain endogenous estrogen levels determine responses to estrogen replacement therapy via regulation of BACE1 and NEP in female Alzheimer’s transgenic mice R Li, P He, J Cui, M Staufenbiel, N Harada, Y Shen Molecular neurobiology 47, 857-867, 2013 | 97 | 2013 |
Long-term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of β-secretase in a mouse model of Alzheimer’s disease P He, X Cheng, M Staufenbiel, R Li, Y Shen PloS one 8 (2), e55091, 2013 | 93 | 2013 |
High activities of BACE1 in brains with mild cognitive impairment X Cheng, P He, T Lee, H Yao, R Li, Y Shen The American journal of pathology 184 (1), 141-147, 2014 | 90 | 2014 |
Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease M Ewers, X Cheng, Z Zhong, HF Nural, C Walsh, T Meindl, SJ Teipel, ... Journal of Alzheimer's Disease 25 (2), 373-381, 2011 | 72 | 2011 |
Distinct destructive signal pathways of neuronal death in Alzheimer's disease Y Shen, P He, Z Zhong, C McAllister, K Lindholm Trends in molecular medicine 12 (12), 574-579, 2006 | 58 | 2006 |
Toxic oligomeric alpha-synuclein variants present in human Parkinson’s disease brains are differentially generated in mammalian cell models W Xin, S Emadi, S Williams, Q Liu, P Schulz, P He, NB Alam, J Wu, ... Biomolecules 5 (3), 1634-1651, 2015 | 50 | 2015 |
Deficiency of GDNF receptor GFRα1 in Alzheimer's neurons results in neuronal death Y Konishi, LB Yang, P He, K Lindholm, B Lu, R Li, Y Shen Journal of Neuroscience 34 (39), 13127-13138, 2014 | 49 | 2014 |
Genetic deletion of TNFRII gene enhances the Alzheimer-like pathology in an APP transgenic mouse model via reduction of phosphorylated IκBα H Jiang, P He, J Xie, M Staufenbiel, R Li, Y Shen Human Molecular Genetics 23 (18), 4906-4918, 2014 | 43 | 2014 |
Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients H Nural, P He, T Beach, L Sue, W Xia, Y Shen Molecular neurodegeneration 4, 1-9, 2009 | 39 | 2009 |
GABAA receptor-mediated excitation in dissociated neurons from human hypothalamic hamartomas J Wu, J DeChon, F Xue, G Li, K Ellsworth, M Gao, Q Liu, K Yang, C Zheng, ... Experimental neurology 213 (2), 397-404, 2008 | 37 | 2008 |
Occludin deficiency with BACE1 elevation in cerebral amyloid angiopathy X Cheng, P He, H Yao, Q Dong, R Li, Y Shen Neurology 82 (19), 1707-1715, 2014 | 36 | 2014 |