Lung-function trajectories leading to chronic obstructive pulmonary disease P Lange, B Celli, A Agustí, G Boje Jensen, M Divo, R Faner, S Guerra, ... New England Journal of Medicine 373 (2), 111-122, 2015 | 1335 | 2015 |
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD K Mizumura, SM Cloonan, K Nakahira, AR Bhashyam, M Cervo, T Kitada, ... The Journal of clinical investigation 124 (9), 3987-4003, 2014 | 575 | 2014 |
The cell biology of leukocyte-mediated proteolysis CA Owen, EJ Campbell Journal of leukocyte biology 65 (2), 137-150, 1999 | 540 | 1999 |
Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases. CA Owen, MA Campbell, PL Sannes, SS Boukedes, EJ Campbell The Journal of cell biology 131 (3), 775-789, 1995 | 504 | 1995 |
Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis VJ Craig, L Zhang, JS Hagood, CA Owen American journal of respiratory cell and molecular biology 53 (5), 585-600, 2015 | 435 | 2015 |
CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice T Maeno, AMG Houghton, PA Quintero, S Grumelli, CA Owen, SD Shapiro The Journal of Immunology 178 (12), 8090-8096, 2007 | 349 | 2007 |
Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction HC Lam, SM Cloonan, AR Bhashyam, JA Haspel, A Singh, ... The Journal of clinical investigation 123 (12), 5212-5230, 2013 | 307 | 2013 |
Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase CA Owen, Z Hu, C Lopez-Otin, SD Shapiro The Journal of Immunology 172 (12), 7791-7803, 2004 | 305 | 2004 |
Neutrophil elastase in human atherosclerotic plaques: production by macrophages CM Dollery, CA Owen, GK Sukhova, A Krettek, SD Shapiro, P Libby Circulation 107 (22), 2829-2836, 2003 | 279 | 2003 |
Bioactive proteinase 3 on the cell surface of human neutrophils: quantification, catalytic activity, and susceptibility to inhibition EJ Campbell, MA Campbell, CA Owen The Journal of Immunology 165 (6), 3366-3374, 2000 | 233 | 2000 |
Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice SM Cloonan, K Glass, ME Laucho-Contreras, AR Bhashyam, M Cervo, ... Nature medicine 22 (2), 163-174, 2016 | 232 | 2016 |
Leukocyte proteinases in wound healing: roles in physiologic and pathologic processes B Barrick, EJ Campbell, CA Owen Wound Repair and Regeneration 7 (6), 410-422, 1999 | 211 | 1999 |
Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease CA Owen International journal of chronic obstructive pulmonary disease 3 (2), 253-268, 2008 | 200 | 2008 |
Cytokines regulate membrane-bound leukocyte elastase on neutrophils: a novel mechanism for effector activity CA Owen, MA Campbell, SS Boukedes, EJ Campbell American Journal of Physiology-Lung Cellular and Molecular Physiology 272 (3 …, 1997 | 176 | 1997 |
Quantum proteolysis by neutrophils: Implications for pulmonary emphysema in alpha-1-antitrypsin deficiency EJ Campbell, MA Campbell, SS Boukedes, CA Owen Chest 117 (5 Suppl 1), 303S-303S, 2000 | 168 | 2000 |
Protective role for club cell secretory protein-16 (CC16) in the development of COPD ME Laucho-Contreras, F Polverino, K Gupta, KL Taylor, E Kelly, ... European Respiratory Journal 45 (6), 1544-1556, 2015 | 166 | 2015 |
Inflammation in COPD: implications for management S Sethi, DA Mahler, P Marcus, CA Owen, B Yawn, S Rennard The American journal of medicine 125 (12), 1162-1170, 2012 | 156 | 2012 |
ADAM-33 surfaces as an asthma gene. SD Shapiro, CA Owen The New England journal of medicine 347 (12), 936-938, 2002 | 146 | 2002 |
Angiotensin II generation at the cell surface of activated neutrophils: novel cathepsin G-mediated catalytic activity that is resistant to inhibition CA Owen, EJ Campbell The Journal of Immunology 160 (3), 1436-1443, 1998 | 146 | 1998 |
Association of clonal hematopoiesis with chronic obstructive pulmonary disease PG Miller, D Qiao, J Rojas-Quintero, MC Honigberg, AS Sperling, ... Blood, The Journal of the American Society of Hematology 139 (3), 357-368, 2022 | 142 | 2022 |