Differential control of peripheral circadian rhythms by suprachiasmatic-dependent neural signals H Guo, JMK Brewer, A Champhekar, RBS Harris, EL Bittman Proceedings of the National Academy of Sciences 102 (8), 3111-3116, 2005 | 294 | 2005 |
Positive feedback between PU. 1 and the cell cycle controls myeloid differentiation HY Kueh, A Champhekar, SL Nutt, MB Elowitz, EV Rothenberg Science 341 (6146), 670-673, 2013 | 279 | 2013 |
Conserved interferon-γ signaling drives clinical response to immune checkpoint blockade therapy in melanoma CS Grasso, J Tsoi, M Onyshchenko, G Abril-Rodriguez, ... Cancer cell 38 (4), 500-515. e3, 2020 | 273 | 2020 |
Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells JB Samon, A Champhekar, LM Minter, JC Telfer, L Miele, A Fauq, P Das, ... Blood, The Journal of the American Society of Hematology 112 (5), 1813-1821, 2008 | 242 | 2008 |
The'K'selected oligophilic bacteria: a key to uncultured diversity? M Watve, V Shejval, C Sonawane, M Rahalkar, A Matapurkar, Y Shouche, ... Current science, 1535-1542, 2000 | 142 | 2000 |
Overcoming genetically based resistance mechanisms to PD-1 blockade DY Torrejon, G Abril-Rodriguez, AS Champhekar, J Tsoi, KM Campbell, ... Cancer discovery 10 (8), 1140-1157, 2020 | 111 | 2020 |
GATA-3 dose-dependent checkpoints in early T cell commitment DD Scripture-Adams, SS Damle, L Li, KJ Elihu, S Qin, AM Arias, RR Butler, ... The Journal of Immunology 193 (7), 3470-3491, 2014 | 81 | 2014 |
Type I and type II interferon coordinately regulate suppressive dendritic cell fate and function during viral persistence CR Cunningham, A Champhekar, MV Tullius, BJ Dillon, A Zhen, ... PloS pathogens 12 (1), e1005356, 2016 | 77 | 2016 |
Forging T-lymphocyte identity: intersecting networks of transcriptional control EV Rothenberg, J Ungerbäck, A Champhekar Advances in immunology 129, 109-174, 2016 | 71 | 2016 |
Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU. 1 A Champhekar, SS Damle, G Freedman, S Carotta, SL Nutt, ... Genes & development 29 (8), 832-848, 2015 | 65 | 2015 |
Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti–PD-1 therapy YJ Kim, KM Sheu, J Tsoi, G Abril-Rodriguez, E Medina, CS Grasso, ... The Journal of clinical investigation 131 (12), 2021 | 43 | 2021 |
Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment EV Rothenberg, A Champhekar, S Damle, MM Del Real, HY Kueh, L Li, ... Cold Spring Harbor symposia on quantitative biology 78, 31-41, 2013 | 19 | 2013 |
IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing Y Pan, JW Phillips, BD Zhang, M Noguchi, E Kutschera, J McLaughlin, ... Proceedings of the National Academy of Sciences 120 (21), e2221116120, 2023 | 15 | 2023 |
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses G Monticone, Z Huang, F Csibi, S Leit, D Ciccone, AS Champhekar, ... Frontiers in Immunology 13, 987298, 2022 | 8 | 2022 |
IND-enabling studies for a clinical trial to genetically program a persistent cancer-targeted immune system C Puig-Saus, G Parisi, A Garcia-Diaz, PE Krystofinski, S Sandoval, ... Clinical Cancer Research 25 (3), 1000-1011, 2019 | 8 | 2019 |
ERK mediates interferon gamma-induced melanoma cell death A Champhekar, R Heymans, J Saco, G Turon Font, C Gonzalez, A Gao, ... Molecular Cancer 22 (1), 165, 2023 | 6 | 2023 |
Remodeling of the tumor microenvironment through PAK4 inhibition sensitizes tumors to immune checkpoint blockade G Abril-Rodriguez, DY Torrejon, D Karin, KM Campbell, E Medina, ... Cancer research communications 2 (10), 1214-1228, 2022 | 5 | 2022 |
Tumor cell–autonomous SHP2 contributes to immune suppression in metastatic breast cancer H Chen, GM Cresswell, S Libring, MG Ayers, J Miao, ZY Zhang, L Solorio, ... Cancer Research Communications 2 (10), 1104-1118, 2022 | 4 | 2022 |
IRIS: Big data-informed discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing Y Pan, AH Lee, HT Yang, Y Wang, Y Xu, KE Kadash-Edmondson, ... bioRxiv, 843268, 2019 | 2 | 2019 |
Overcoming genetically based resistance mechanisms to PD-1 blockade. DY Torrejon, G Abril-Rodriguez, J Tsoi, A Champhekar, A Kalbasi, ... Journal of Clinical Oncology 37 (15_suppl), 2584-2584, 2019 | 1 | 2019 |