A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS WYC Huang, S Alvarez, Y Kondo, YK Lee, JK Chung, HYM Lam, ... Science 363 (6431), 1098-1103, 2019 | 296 | 2019 |
H-Ras forms dimers on membrane surfaces via a protein–protein interface WC Lin, L Iversen, HL Tu, C Rhodes, SM Christensen, JS Iwig, ... Proceedings of the National Academy of Sciences 111 (8), 2996-3001, 2014 | 180 | 2014 |
Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner AR Lowe, JH Tang, J Yassif, M Graf, WYC Huang, JT Groves, K Weis, ... Elife 4, e04052, 2015 | 142 | 2015 |
Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS WYC Huang, Q Yan, WC Lin, JK Chung, SD Hansen, SM Christensen, ... Proceedings of the National Academy of Sciences 113 (29), 8218-8223, 2016 | 117 | 2016 |
E-cadherin junction formation involves an active kinetic nucleation process KH Biswas, KL Hartman, C Yu, OJ Harrison, H Song, AW Smith, ... Proceedings of the National Academy of Sciences 112 (35), 10932-10937, 2015 | 108 | 2015 |
Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions JK Chung, WYC Huang, CB Carbone, LM Nocka, AN Parikh, RD Vale, ... Biophysical Journal 120 (7), 1257-1265, 2021 | 50 | 2021 |
Stochastic geometry sensing and polarization in a lipid kinase–phosphatase competitive reaction SD Hansen, WYC Huang, YK Lee, P Bieling, SM Christensen, JT Groves Proceedings of the National Academy of Sciences 116 (30), 15013-15022, 2019 | 40 | 2019 |
Steric zipper formed by hydrophobic peptide fragment of Syrian hamster prion protein HM Cheng, TWT Tsai, WYC Huang, HK Lee, HY Lian, FC Chou, Y Mou, ... Biochemistry 50 (32), 6815-6823, 2011 | 34 | 2011 |
Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation WYC Huang, JA Ditlev, HK Chiang, MK Rosen, JT Groves Journal of the American Chemical Society 139 (49), 18009-18015, 2017 | 32 | 2017 |
Dynamic Scaling Analysis of Molecular Motion within the LAT: Grb2: SOS Protein Network on Membranes WYC Huang, HK Chiang, JT Groves Biophysical Journal 113 (8), 1807-1813, 2017 | 25 | 2017 |
Cytoplasmic organization promotes protein diffusion in Xenopus extracts WYC Huang, X Cheng, JE Ferrell Jr Nature Communications 13 (1), 5599, 2022 | 21 | 2022 |
Relating cellular signaling timescales to single-molecule kinetics: A first-passage time analysis of Ras activation by SOS WYC Huang, S Alvarez, Y Kondo, J Kuriyan, JT Groves Proceedings of the National Academy of Sciences 118 (45), e2103598118, 2021 | 15 | 2021 |
Stochasticity and positive feedback enable enzyme kinetics at the membrane to sense reaction size AA Lee, WYC Huang, SD Hansen, NH Kim, S Alvarez, JT Groves Proceedings of the National Academy of Sciences 118 (47), e2103626118, 2021 | 14 | 2021 |
Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting YH Hwang Fu, WYC Huang, K Shen, JT Groves, T Miller, S Shan Elife 6, e25885, 2017 | 12 | 2017 |
Proceedings of the fifth international RASopathies symposium: When development and cancer intersect KA Rauen, L Schoyer, L Schill, B Stronach, J Albeck, BS Andresen, ... American Journal of Medical Genetics Part A 176 (12), 2924-2929, 2018 | 11 | 2018 |
Robust trigger wave speed in Xenopus cytoplasmic extracts JH Huang, Y Chen, WYC Huang, S Tabatabaee, JE Ferrell Jr Nature Communications 15 (1), 5782, 2024 | 2 | 2024 |
Membrane localization accelerates association under conditions relevant to cellular signaling WYC Huang, SG Boxer, JE Ferrell Jr Proceedings of the National Academy of Sciences 121 (10), e2319491121, 2024 | 1 | 2024 |
Depletion of Water Molecules Near the End Stage of Steric Zipper Formation HM Cheng, WYC Huang, TWT Tsai, Y Mou, JCH Chao, JCC Chan Journal of the Chinese Chemical Society 60 (7), 794-800, 2013 | 1 | 2013 |
Measuring Molecular Diffusion in Self-Organizing Xenopus Extracts by Fluorescence Correlation Spectroscopy WYC Huang, JE Ferrell Jr, X Cheng Cell Cycle Control: Methods and Protocols, 107-115, 2024 | | 2024 |