LZTR1 is a regulator of RAS ubiquitination and signaling JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ... Science 362 (6419), 1171-1177, 2018 | 183 | 2018 |
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ... Nature 581 (7808), 316-322, 2020 | 166 | 2020 |
A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs E Girardi, A César-Razquin, S Lindinger, K Papakostas, J Konecka, ... Nature chemical biology 16 (4), 469-478, 2020 | 117 | 2020 |
Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import E Girardi, G Agrimi, U Goldmann, G Fiume, S Lindinger, V Sedlyarov, ... Nature communications 11 (1), 6145, 2020 | 99 | 2020 |
Targeted degradation of SLC transporters reveals amenability of multi-pass transmembrane proteins to ligand-induced proteolysis A Bensimon, MD Pizzagalli, F Kartnig, V Dvorak, P Essletzbichler, ... Cell chemical biology 27 (6), 728-739. e9, 2020 | 82 | 2020 |
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ... Cell host & microbe 23 (6), 766-774. e5, 2018 | 79 | 2018 |
mTOR senses environmental cues to shape the fibroblast-like synoviocyte response to inflammation T Karonitsch, RK Kandasamy, F Kartnig, B Herdy, K Dalwigk, ... Cell Reports 23 (7), 2157-2167, 2018 | 60 | 2018 |
Immunogenicity and safety of a fourth COVID-19 vaccination in rituximab-treated patients: an open-label extension study D Mrak, E Simader, D Sieghart, P Mandl, H Radner, T Perkmann, ... Annals of the Rheumatic Diseases 81 (12), 1750-1756, 2022 | 33 | 2022 |
Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial D Mrak, D Sieghart, E Simader, S Tobudic, H Radner, P Mandl, L Göschl, ... Nature Communications 13 (1), 5362, 2022 | 28 | 2022 |
FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes B Brandstetter, K Dalwigk, A Platzer, B Niederreiter, F Kartnig, A Fischer, ... Laboratory Investigation 99 (5), 648-658, 2019 | 25 | 2019 |
Safety and immunogenicity of a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases compared with healthy controls F Kartnig, D Mrak, E Simader, S Tobudic, H Radner, P Mandl, L Göschl, ... Annals of the Rheumatic Diseases 82 (2), 292-300, 2023 | 21 | 2023 |
The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection A Moskovskich, U Goldmann, F Kartnig, S Lindinger, J Konecka, G Fiume, ... Scientific reports 9 (1), 10471, 2019 | 21 | 2019 |
Cytokine-directed cellular cross-talk imprints synovial pathotypes in rheumatoid arthritis M Kugler, M Dellinger, F Kartnig, L Müller, T Preglej, LX Heinz, E Simader, ... Annals of the Rheumatic Diseases 82 (9), 1142-1152, 2023 | 17 | 2023 |
Cell-surface SLC nucleoside transporters and purine levels modulate BRD4-dependent chromatin states KC Li, E Girardi, F Kartnig, S Grosche, T Pemovska, JW Bigenzahn, ... Nature metabolism 3 (5), 651-664, 2021 | 13 | 2021 |
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity A Boeszoermenyi, L Bernaleau, X Chen, F Kartnig, M Xie, H Zhang, ... Nature Communications 14 (1), 6626, 2023 | 12 | 2023 |
Metabolic drug survey highlights cancer cell dependencies and vulnerabilities T Pemovska, JW Bigenzahn, I Srndic, A Lercher, A Bergthaler, ... Nature Communications 12 (1), 7190, 2021 | 12 | 2021 |
Reactogenicity and immunogenicity of the second COVID-19 vaccination in patients with inborn errors of immunity or mannan-binding lectin deficiency L Göschl, D Mrak, K Grabmeier-Pfistershammer, K Stiasny, H Haslacher, ... Frontiers in Immunology 13, 974987, 2022 | 9 | 2022 |
Accelerated waning of immune responses to a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases D Mrak, F Kartnig, D Sieghart, E Simader, H Radner, P Mandl, L Göschl, ... Journal of Autoimmunity 135, 102981, 2023 | 8 | 2023 |
A systematic genetic interaction map of human solute carriers assigns a role to SLC25A51/MCART1 in mitochondrial NAD uptake E Girardi, G Fiume, U Goldmann, C Sin, F Müller, S Lindinger, ... bioRxiv, 2020.08. 31.275818, 2020 | 7 | 2020 |
Amino Acids Fueling Fibroblast‐Like Synoviocyte Activation and Arthritis By Regulating Chemokine Expression and Leukocyte Migration T Karonitsch, V Saferding, M Kieler, K von Dalwigk, A Tosevska, G Heller, ... Arthritis & Rheumatology 76 (4), 531-540, 2024 | 5 | 2024 |