| R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters PA Ginno, PL Lott, HC Christensen, I Korf, F Chédin Molecular cell 45 (6), 814-825, 2012 | 852 | 2012 |
| R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells K Yu, F Chedin, CL Hsieh, TE Wilson, MR Lieber Nature immunology 4 (5), 442-451, 2003 | 818 | 2003 |
| The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a F Chedin, MR Lieber, CL Hsieh Proceedings of the National Academy of Sciences 99 (26), 16916-16921, 2002 | 633 | 2002 |
| Comprehensive proteomic analysis of mesenchymal stem cell exosomes reveals modulation of angiogenesis via nuclear factor-kappaB signaling JD Anderson, HJ Johansson, CS Graham, M Vesterlund, MT Pham, ... Stem cells 34 (3), 601-613, 2016 | 518 | 2016 |
| Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals LA Sanz, SR Hartono, YW Lim, S Steyaert, A Rajpurkar, PA Ginno, X Xu, ... Molecular cell 63 (1), 167-178, 2016 | 502 | 2016 |
| GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination PA Ginno, YW Lim, PL Lott, I Korf, F Chédin Genome research 23 (10), 1590-1600, 2013 | 374 | 2013 |
| Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage CT Stork, M Bocek, MP Crossley, J Sollier, LA Sanz, F Chedin, T Swigut, ... Elife 5, e17548, 2016 | 280 | 2016 |
| Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family ZX Chen, JR Mann, CL Hsieh, AD Riggs, F Chédin Journal of cellular biochemistry 95 (5), 902-917, 2005 | 274 | 2005 |
| Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation Y Yang, KM McBride, S Hensley, Y Lu, F Chedin, MT Bedford Molecular cell 53 (3), 484-497, 2014 | 260 | 2014 |
| Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L MS Kareta, ZM Botello, JJ Ennis, C Chou, F Chédin Journal of Biological Chemistry 281 (36), 25893-25902, 2006 | 260 | 2006 |
| Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein N Nady, A Lemak, JR Walker, GV Avvakumov, MS Kareta, M Achour, ... Journal of Biological Chemistry 286 (27), 24300-24311, 2011 | 236 | 2011 |
| The DNMT3 family of mammalian de novo DNA methyltransferases F Chédin Progress in molecular biology and translational science 101, 255-285, 2011 | 223 | 2011 |
| Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region EW Loomis, LA Sanz, F Chédin, PJ Hagerman PLoS genetics 10 (4), e1004294, 2014 | 216 | 2014 |
| Nascent connections: R-loops and chromatin patterning F Chédin Trends in Genetics 32 (12), 828-838, 2016 | 210 | 2016 |
| High-resolution, strand-specific R-loop mapping via S9. 6-based DNA–RNA immunoprecipitation and high-throughput sequencing LA Sanz, F Chédin Nature protocols 14 (6), 1734-1755, 2019 | 196 | 2019 |
| Genome-wide DNA hypomethylation and RNA: DNA hybrid accumulation in Aicardi–Goutières syndrome YW Lim, LA Sanz, X Xu, SR Hartono, F Chedin Elife 4, e08007, 2015 | 184 | 2015 |
| R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation WT Powell, RL Coulson, ML Gonzales, FK Crary, SS Wong, S Adams, ... Proceedings of the National Academy of Sciences 110 (34), 13938-13943, 2013 | 177 | 2013 |
| DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo BL Wienholz, MS Kareta, AH Moarefi, CA Gordon, PA Ginno, F Chédin PLoS genetics 6 (9), e1001106, 2010 | 166 | 2010 |
| Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis X Zhang, HC Chiang, Y Wang, C Zhang, S Smith, X Zhao, SJ Nair, ... Nature communications 8 (1), 15908, 2017 | 154 | 2017 |
| DNA Topoisomerase I differentially modulates R-loops across the human genome SG Manzo, SR Hartono, LA Sanz, J Marinello, S De Biasi, A Cossarizza, ... Genome biology 19, 1-18, 2018 | 152 | 2018 |
